Bailey Tischer
@baileytischer.bsky.social
Chemistry and Biology at MIT | Class of 2026 | Li Lab at @whiteheadinstitute.bsky.social
Reposted by Bailey Tischer
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
www.biorxiv.org
October 26, 2025 at 5:15 PM
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Reposted by Bailey Tischer
Complexity is a consequence of the fact that it’s easier to add than to subtract.
Take evolution of lungs from swim bladders as an example. A lungfish gradually emerges arising from its competitive advantages in living in and out of water.
No creature with lungs has reversed the process.
Take evolution of lungs from swim bladders as an example. A lungfish gradually emerges arising from its competitive advantages in living in and out of water.
No creature with lungs has reversed the process.
May 31, 2025 at 4:42 PM
Complexity is a consequence of the fact that it’s easier to add than to subtract.
Take evolution of lungs from swim bladders as an example. A lungfish gradually emerges arising from its competitive advantages in living in and out of water.
No creature with lungs has reversed the process.
Take evolution of lungs from swim bladders as an example. A lungfish gradually emerges arising from its competitive advantages in living in and out of water.
No creature with lungs has reversed the process.
Reposted by Bailey Tischer
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org
March 10, 2025 at 1:28 PM
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Reposted by Bailey Tischer
Our latest: uncovering hierarchical design rules for cis-regulatory elements with a high-throughput screen
CRE activity follows multiplicative modular rules, tuned by spacing & positioning
Enables engineering synthetic CREs for predictable tissue patterning
www.biorxiv.org/content/10.1...
CRE activity follows multiplicative modular rules, tuned by spacing & positioning
Enables engineering synthetic CREs for predictable tissue patterning
www.biorxiv.org/content/10.1...
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org
March 10, 2025 at 4:19 AM
Our latest: uncovering hierarchical design rules for cis-regulatory elements with a high-throughput screen
CRE activity follows multiplicative modular rules, tuned by spacing & positioning
Enables engineering synthetic CREs for predictable tissue patterning
www.biorxiv.org/content/10.1...
CRE activity follows multiplicative modular rules, tuned by spacing & positioning
Enables engineering synthetic CREs for predictable tissue patterning
www.biorxiv.org/content/10.1...