Badr Sokrat
@badrsokrat.bsky.social
Postdoctoral Research Associate at NYU Pain Research Center | Investigating GPCR signaling, trafficking, and their role in pain modulation | Passionate about molecular pharmacology and cellular signaling.
Reposted by Badr Sokrat
Excited to share Bunnett lab's work on targeting compartmentalized GPCR signaling! Using endosome-accumulating nanoparticles, they selectively blocked intracellular PAR2, achieving complete, long-lasting pain relief in inflammatory disease models.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Nanomedicines targeting protease-activated receptor 2 in endosomes provide sustained analgesia | PNAS
Although many internalized G protein-coupled receptors (GPCRs) continue to signal,
the mechanisms and outcomes of intracellular GPCR signaling are ...
www.pnas.org
October 13, 2025 at 5:52 PM
Excited to share Bunnett lab's work on targeting compartmentalized GPCR signaling! Using endosome-accumulating nanoparticles, they selectively blocked intracellular PAR2, achieving complete, long-lasting pain relief in inflammatory disease models.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Excited to share that I participated in the Annual Molecular Pathobiology Innovative Research Symposium at NYU and received an award for my flash talk presentation:
“Compartmentalized intracellular signaling of the prostaglandin EP4 receptor contributes to pain.”
#research #GPCR #pain #science
“Compartmentalized intracellular signaling of the prostaglandin EP4 receptor contributes to pain.”
#research #GPCR #pain #science
June 2, 2025 at 8:05 PM
Reposted by Badr Sokrat
PRC Journal Club! #FlashbackFridays Flash back to earlier this week to a really interesting discussion led by @badrsokrat.bsky.social on endosomal signaling in opioid receptors. Click the article below to join the discussion. www.biorxiv.org/content/10.1...
April 11, 2025 at 8:54 PM
PRC Journal Club! #FlashbackFridays Flash back to earlier this week to a really interesting discussion led by @badrsokrat.bsky.social on endosomal signaling in opioid receptors. Click the article below to join the discussion. www.biorxiv.org/content/10.1...
Reposted by Badr Sokrat
PRC Highlight: Thank you to the Molecular Pathobiology for hosting the Birthday Tea Time #Partaayyy! Happy Birthday 🎉🎁🎈🎊🎂 @taeseonwoo.bsky.social @badrsokrat.bsky.social @tonelloraquel.bsky.social !!! #PRC #Painresearchcenter #boomerang ☕️🫖
February 27, 2025 at 8:38 PM
PRC Highlight: Thank you to the Molecular Pathobiology for hosting the Birthday Tea Time #Partaayyy! Happy Birthday 🎉🎁🎈🎊🎂 @taeseonwoo.bsky.social @badrsokrat.bsky.social @tonelloraquel.bsky.social !!! #PRC #Painresearchcenter #boomerang ☕️🫖