Christopher Azaldegui
@azaldegui.bsky.social
Postdoc @ Stanford/SLAC developing cryoCLEM
Reposted by Christopher Azaldegui
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
November 19, 2025 at 4:18 PM
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
Reposted by Christopher Azaldegui
Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage.
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
Stress changes the material state of a bacterial biomolecular condensate and shifts its function from mRNA decay to storage - Nature Communications
Bacterial ribonucleoprotein bodies are dynamic biomolecular condensates that play roles in RNA metabolism. Here, Ortiz-Rodríguez et al. show that, under stress, these condensates shift from a liquid s...
www.nature.com
November 14, 2025 at 4:32 PM
Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage.
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
Reposted by Christopher Azaldegui
New PrePrint from the Vecchiarelli and Mosalaganti (@shyamalm.bsky.social) labs! 🧵
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
Engineering Spatial Control of Bacterial Organelles
Bacteria were once thought to lack organelles, but it is now clear they confine cellular reactions using an array of membrane- and protein-based compartments. A central question, however, is how bacte...
www.biorxiv.org
September 23, 2025 at 5:38 PM
New PrePrint from the Vecchiarelli and Mosalaganti (@shyamalm.bsky.social) labs! 🧵
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
Reposted by Christopher Azaldegui
Engineering Spatial Control of Bacterial Organelles https://www.biorxiv.org/content/10.1101/2025.09.22.677801v1
September 23, 2025 at 3:18 AM
Engineering Spatial Control of Bacterial Organelles https://www.biorxiv.org/content/10.1101/2025.09.22.677801v1
Reposted by Christopher Azaldegui
Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells https://www.biorxiv.org/content/10.1101/2025.09.19.677416v1
September 21, 2025 at 3:48 PM
Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells https://www.biorxiv.org/content/10.1101/2025.09.19.677416v1
Reposted by Christopher Azaldegui
Dps binds and protects DNA in starved Escherichia coli with minimal effect on chromosome accessibility, dynamics and organisation https://www.biorxiv.org/content/10.1101/2025.08.31.673347v1
September 5, 2025 at 2:48 AM
Dps binds and protects DNA in starved Escherichia coli with minimal effect on chromosome accessibility, dynamics and organisation https://www.biorxiv.org/content/10.1101/2025.08.31.673347v1
Reposted by Christopher Azaldegui
New @biorxiv-microbiol.bsky.social PrePrint from the Vecchiarelli Lab! 🧵
In collaboration with Jian Liu's lab at Johns Hopkins
doi.org/10.1101/2025...
Congratulations to first author Jordan Byrne!
@sickbyrne.bsky.social
P.S. She is looking for jobs!
Pls ReSkeet
In collaboration with Jian Liu's lab at Johns Hopkins
doi.org/10.1101/2025...
Congratulations to first author Jordan Byrne!
@sickbyrne.bsky.social
P.S. She is looking for jobs!
Pls ReSkeet
Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning
The maintenance of carboxysome distribution (Mcd) system comprises the proteins McdA and McdB, which spatially organize carboxysomes to promote efficient carbon fixation and ensure their equal inherit...
doi.org
May 30, 2025 at 8:53 PM
New @biorxiv-microbiol.bsky.social PrePrint from the Vecchiarelli Lab! 🧵
In collaboration with Jian Liu's lab at Johns Hopkins
doi.org/10.1101/2025...
Congratulations to first author Jordan Byrne!
@sickbyrne.bsky.social
P.S. She is looking for jobs!
Pls ReSkeet
In collaboration with Jian Liu's lab at Johns Hopkins
doi.org/10.1101/2025...
Congratulations to first author Jordan Byrne!
@sickbyrne.bsky.social
P.S. She is looking for jobs!
Pls ReSkeet
Reposted by Christopher Azaldegui
Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning https://www.biorxiv.org/content/10.1101/2025.05.22.655647v1
May 23, 2025 at 3:17 AM
Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning https://www.biorxiv.org/content/10.1101/2025.05.22.655647v1
Reposted by Christopher Azaldegui
The hooding ceremony was a chance to celebrate these 2024 🎓 graduates all over again!
May 4, 2025 at 12:56 PM
The hooding ceremony was a chance to celebrate these 2024 🎓 graduates all over again!
Reposted by Christopher Azaldegui
New @biorxiv-microbiol.bsky.social Pre-Print from the Vecchiarelli Lab! 🧵
doi.org/10.1101/2025...
Congratulations to first author Claire Dudley!
@claire-dudley.bsky.social
Pls ReSkeet
doi.org/10.1101/2025...
Congratulations to first author Claire Dudley!
@claire-dudley.bsky.social
Pls ReSkeet
pubs.acs.org
April 25, 2025 at 6:52 PM
New @biorxiv-microbiol.bsky.social Pre-Print from the Vecchiarelli Lab! 🧵
doi.org/10.1101/2025...
Congratulations to first author Claire Dudley!
@claire-dudley.bsky.social
Pls ReSkeet
doi.org/10.1101/2025...
Congratulations to first author Claire Dudley!
@claire-dudley.bsky.social
Pls ReSkeet