Ali Azadbakht
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azadbakht.bsky.social
Ali Azadbakht
@azadbakht.bsky.social
Soft Matter Physicist, interested in Optical Microscopy
There, we didn’t use sticky particles — it makes the experiments much easier to perform. It’s similar to the approach in the paper below:
pubs.acs.org/doi/full/10....
Despite some limitations, the method is experimentally much more straightforward.
Nonadditivity in Many-Body Interactions between Membrane-Deforming Spheres Increases Disorder
Membrane-induced interactions play an important role in organizing membrane proteins. Measurements of the interactions between two and three membrane deforming objects have revealed their nonadditive ...
pubs.acs.org
July 2, 2025 at 1:36 PM
By the way, thank you for the very clear and simple explanation in the video. I keep recommending it to people whenever I talk about my PhD work :)
July 2, 2025 at 1:12 PM
It is super interesting indeed, even for the linear order! Our last piece is still in progress — there we explored different shapes, and yes, we were definitely betting on it :))
July 2, 2025 at 1:11 PM
🎥 For more background about this interaction, check out Markus Deserno’s great talk (link below) @markusdeserno.bsky.social

tinyurl.com/3hse4jdj

and the related papers from our group listed:
tinyurl.com/bddhrcax
tinyurl.com/nh9p9bbc
tinyurl.com/38dhasdw
Markus Deserno - A Physicist's View on Biological Membranes
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
tinyurl.com
July 2, 2025 at 8:38 AM
🔗 Paper link below if you’d like the details.
doi.org/10.1039/d4sm...

🙌 Thanks to @danielajkraft.bsky.social for brilliant work and guidance, and to @leidenphysics.bsky.social for funding the project. Interested in membrane mechanics or how we perform experiments? Feel free to contact me.
Repulsions and attractions between membrane-deforming spheres, Janus-particles, and opposite tube-like deformations in giant unilamellar vesicles
Lipid membrane deformations have been predicted to lead to indirect forces between the objects that induce these deformations. Recent experimental measurements have found an attractive interaction bet...
doi.org
July 2, 2025 at 8:38 AM
💡 What we found
Gentle dents repel bumps, but deeper dents attract them.
The switch happens around a critical curvature—as predicted by theory but never measured before.
Forces are small yet strong enough to steer how curvature-making proteins cluster.
July 2, 2025 at 8:38 AM
Model system = giant lipid vesicles + membrane adhesive beads + an optical-tweezer-pulled nanotube. Track the bead, map the interaction energy in comparison with thermal motion 🌌➡️🫧
July 2, 2025 at 8:38 AM
What type of stage is this? Looks amazing ;)
December 12, 2024 at 8:19 PM