Ayush Mistry
ayushmistry.bsky.social
Ayush Mistry
@ayushmistry.bsky.social
PhD candidate, biochem x mol bio @slusom | everything DNA repair when in lab | science policy, scientific outreach, teaching, & sleeping when not in lab.
Reposted by Ayush Mistry
How are Rad51 filaments formed during Homologous Recombination?

Jaigeeth Deveryshetty and Ayush Mistry describe the mechanism through the lens of Rad52, the yeast homolog of human BRCA2.

urldefense.com/v3/__https:/...
Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Nature Communications - The mediator protein Rad52 promotes Rad51 binding onto RPA-coated DNA to initiate homologous recombination. Here, the authors show that Rad52 sorts Rad51 into monomers and...
urldefense.com
July 21, 2025 at 12:34 PM
Reposted by Ayush Mistry
Our story detailing how asymmetry in nitrogenase-like proteins regulate electron transfer reactions is finally out! rdcu.be/ejaeK Congratulations to postdoc @rajnandani.bsky.social and fantastic collaborators. Thanks to funding from the Department of Energy and the NIH.
Cryo-EM captures the coordination of asymmetric electron transfer through a di-copper site in DPOR
Nature Communications - CryoEM snapshots of the nitrogenase-like DPOR protein complex captured during turnover reveal that asymmetric conformational changes, substrate recognition, and an interplay...
rdcu.be
April 24, 2025 at 2:11 PM
Considered sharing a new study tracking the effects of deep-sea mining www.nature.com/articles/s41..., AND plugging in my letter that rings similar warning bells with India’s rampant interests in such mining activities www.science.org/doi/10.1126/...
Long-term impact and biological recovery in a deep-sea mining track - Nature
Nature - Long-term impact and biological recovery in a deep-sea mining track
www.nature.com
March 27, 2025 at 5:05 PM