Aylwyn Scally
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aylwyn-scally.bsky.social
Aylwyn Scally
@aylwyn-scally.bsky.social
Human evolutionary genetics, University of Cambridge; Darwin College. 🇮🇪
Suspect you might have to fire up a VPN..
November 15, 2025 at 7:25 AM
This case is just an extension of the ghoulish fascination people have for killers and mass murderers. But I agree the implication that it will help us understand the nature of his evil is deeply misguided.
November 15, 2025 at 7:25 AM
Yeah I'm not particularly opposed to them; I just think the motives for sequencing famous individuals are not scientific. There may in some cases be information of historical interest, albeit limited.
November 15, 2025 at 7:25 AM
I'm not sure we can lay all the blame on the journalists though.. a lot of press releases are thoroughly hyped up when written!

Agree about being vocal about misleading science reports. Although, bluesky is a bit of an echo chamber in this regard.
November 15, 2025 at 1:06 AM
It's entirely understandable that journalists and members of the public are confused. On the one hand we assert, in pursuit of medical funding, that your genome is highly informative about your individual health and future, and on the other hand we say (correctly) that claims like this are bogus.
November 15, 2025 at 12:49 AM
By all means we should counter any such implication. I think however that if we really want to make progress on correcting this kind of public and media misunderstanding, we should start with the assertions made about the potential power of personal genomics.
November 15, 2025 at 12:49 AM
I think we can say confidently that there is zero scientific value in such 'celebrity' genomes, notorious or otherwise, and probably little or no historical value either.
November 15, 2025 at 12:12 AM
I'm not sure there's much to say. It's the latest and most ghoulish in a series of celebrity genomes, none of which have been done with the goal or expectation of answering any scientific question.
November 14, 2025 at 11:57 PM
Yeah, I don't think we are there quite yet, but seems to me all the pieces are in place for natural-language interactive data exploration to be a thing pretty soon. Maybe even voice-driven..
November 13, 2025 at 7:32 PM
Where Python wins for me is that for all its flaws, it remains a much more useful general purpose tool than, say, R. There are very few things for which it's the best solution, but it's rarely terrible.

But FWIW, I'd probably write an awk one-liner for the problem you described :)
November 13, 2025 at 6:59 PM
Seems to me at this stage, or pretty soon, we could feed your initial natural language query into an AI and get the desired outputs. Differences between languages for specific tasks like this are becoming moot.
November 13, 2025 at 6:59 PM
I'm not convinced most of it does..
November 13, 2025 at 5:45 PM
Goebbels presumably had two copies of the variant. Very unfortunate.
November 13, 2025 at 9:31 AM
I say take the win and publish.
November 12, 2025 at 10:10 AM