Vishal Rastogi
@autophagyfasting.bsky.social
Avoid a poor diet, smoking, alcohol, and inactivity to protect long‑term health. These habits block repair systems like autophagy, glymphatic clearance, and immune regulation. Breaking free restores the body’s power to regenerate, adapt, and thrive.
#IntermittentFasting #MetabolicHealth #Autophagy
#IntermittentFasting #MetabolicHealth #Autophagy
February 6, 2026 at 11:39 AM
Avoid a poor diet, smoking, alcohol, and inactivity to protect long‑term health. These habits block repair systems like autophagy, glymphatic clearance, and immune regulation. Breaking free restores the body’s power to regenerate, adapt, and thrive.
#IntermittentFasting #MetabolicHealth #Autophagy
#IntermittentFasting #MetabolicHealth #Autophagy
REM and non-REM sleep work in tandem to restore both body and mind, and progressing through their cycles makes sleep regenerative. If disrupted, the body misses repair, and the brain loses its chance to integrate learning and regulate mood, leaving us less resilient, less focused, and more stressed.
February 6, 2026 at 11:18 AM
REM and non-REM sleep work in tandem to restore both body and mind, and progressing through their cycles makes sleep regenerative. If disrupted, the body misses repair, and the brain loses its chance to integrate learning and regulate mood, leaving us less resilient, less focused, and more stressed.
Dietary fiber—though indigestible—fuels gut bacteria to produce SCFAs, powerful messengers that influence glucose, weight, immunity, and gut integrity. The fiber–microbiota–SCFA axis is a key to preventing chronic disease and optimizing health.
medium.com/@AutophagyFa...
#SCFAs #GutMicrobiome
medium.com/@AutophagyFa...
#SCFAs #GutMicrobiome
Short-chain fatty acids: Gatekeepers of gut and metabolic health
Mechanistic insights into metabolism, immunity, and disease prevention.
medium.com
January 29, 2026 at 10:51 AM
Dietary fiber—though indigestible—fuels gut bacteria to produce SCFAs, powerful messengers that influence glucose, weight, immunity, and gut integrity. The fiber–microbiota–SCFA axis is a key to preventing chronic disease and optimizing health.
medium.com/@AutophagyFa...
#SCFAs #GutMicrobiome
medium.com/@AutophagyFa...
#SCFAs #GutMicrobiome
The Warburg Effect casts cancer as glucose-addicted. But tumors are flexible—able to reprogram and burn ketones when sugar runs low. This adaptability shows that cancer metabolism is dynamic, resilient, and far more complex than the old narrative suggests.
medium.com/@AutophagyFa...
medium.com/@AutophagyFa...
Beyond the Warburg Effect: Metabolic plasticity in cancer cells
Metabolic pathways that reprogram cancer cells’ shift from glucose dependence to ketone utilization.
medium.com
January 13, 2026 at 11:56 AM
The Warburg Effect casts cancer as glucose-addicted. But tumors are flexible—able to reprogram and burn ketones when sugar runs low. This adaptability shows that cancer metabolism is dynamic, resilient, and far more complex than the old narrative suggests.
medium.com/@AutophagyFa...
medium.com/@AutophagyFa...
The key isn’t eliminating sweetness from life—it’s choosing sources that nourish rather than deplete. Fruits, nuts, and naturally sweet alternatives can satisfy cravings without compromising your health.
#AddedSugar #MetabolicHealth
#AddedSugar #MetabolicHealth
January 6, 2026 at 12:44 PM
The key isn’t eliminating sweetness from life—it’s choosing sources that nourish rather than deplete. Fruits, nuts, and naturally sweet alternatives can satisfy cravings without compromising your health.
#AddedSugar #MetabolicHealth
#AddedSugar #MetabolicHealth
In today’s fast-paced world, added sugars sneak into almost everything—from packaged snacks to “healthy” drinks. While they may offer instant gratification, the long-term effects are far from sweet.
#AddedSugar #MetabolicHealth
#AddedSugar #MetabolicHealth
January 6, 2026 at 10:59 AM
In today’s fast-paced world, added sugars sneak into almost everything—from packaged snacks to “healthy” drinks. While they may offer instant gratification, the long-term effects are far from sweet.
#AddedSugar #MetabolicHealth
#AddedSugar #MetabolicHealth
Wishing you all a very Happy New Year! May this new beginning bring you good health, renewed energy, and endless moments of happiness. Let’s step into the year ahead with hope, resilience, and gratitude—embracing fresh opportunities and creating memories that inspire.
January 1, 2026 at 6:03 AM
Wishing you all a very Happy New Year! May this new beginning bring you good health, renewed energy, and endless moments of happiness. Let’s step into the year ahead with hope, resilience, and gratitude—embracing fresh opportunities and creating memories that inspire.
Sleep struggles aren’t only about stress or caffeine—light is a hidden disruptor. Blue light from screens suppresses melatonin, scrambles circadian rhythms, and keeps the brain stuck in “day mode.” Discover why.
medium.com/@AutophagyFa...
#BlueLight #CircadianRhythm #Sleep #Melatonin
medium.com/@AutophagyFa...
#BlueLight #CircadianRhythm #Sleep #Melatonin
Light, sleep, and the modern human: Why blue light keeps you awake
The hidden biology of melatonin suppression and circadian disruption.
medium.com
December 31, 2025 at 9:37 AM
Sleep struggles aren’t only about stress or caffeine—light is a hidden disruptor. Blue light from screens suppresses melatonin, scrambles circadian rhythms, and keeps the brain stuck in “day mode.” Discover why.
medium.com/@AutophagyFa...
#BlueLight #CircadianRhythm #Sleep #Melatonin
medium.com/@AutophagyFa...
#BlueLight #CircadianRhythm #Sleep #Melatonin
Fasting and calorie restriction can reduce systemic inflammation, improve insulin sensitivity, and promote autophagy (cellular repair), thereby lowering the risk of DNA damage and tumor initiation.
#IntermittentFasting #Autophagy #CancerPrevention
#IntermittentFasting #Autophagy #CancerPrevention
December 23, 2025 at 10:41 AM
Fasting and calorie restriction can reduce systemic inflammation, improve insulin sensitivity, and promote autophagy (cellular repair), thereby lowering the risk of DNA damage and tumor initiation.
#IntermittentFasting #Autophagy #CancerPrevention
#IntermittentFasting #Autophagy #CancerPrevention
Fasting strengthens immune resilience by lowering inflammation, improving insulin sensitivity, and triggering autophagy, which clears damaged mitochondria. When this “housekeeping” happens before immune cells divide, they’re more likely to form durable memory rather than short‑lived responses.
December 23, 2025 at 10:40 AM
Fasting strengthens immune resilience by lowering inflammation, improving insulin sensitivity, and triggering autophagy, which clears damaged mitochondria. When this “housekeeping” happens before immune cells divide, they’re more likely to form durable memory rather than short‑lived responses.
Parkinson’s isn’t just a brain disorder—it’s deeply tied to the gut. This article examines the role of dietary strategies and fasting in intervening early and post-diagnosis, with new approaches to delay progression and empower patients.
medium.com/@AutophagyFa...
#GutMicrobiome #ParkinsonDisease
medium.com/@AutophagyFa...
#GutMicrobiome #ParkinsonDisease
From gut microbiome to motor symptoms: The gut–brain axis in Parkinson’s disease progression
Linking prodromal clues to prospects for intervention.
medium.com
December 17, 2025 at 5:04 PM
Parkinson’s isn’t just a brain disorder—it’s deeply tied to the gut. This article examines the role of dietary strategies and fasting in intervening early and post-diagnosis, with new approaches to delay progression and empower patients.
medium.com/@AutophagyFa...
#GutMicrobiome #ParkinsonDisease
medium.com/@AutophagyFa...
#GutMicrobiome #ParkinsonDisease
Your gut is a living ecosystem shaping immunity, metabolism, mood, and cognition. When you understand how food, stress, and daily habits shape your microbiome, you gain real agency over your health.
medium.com/@AutophagyFa...
#IntermittentFasting #GutMicrobiome #MetabolicHealth
medium.com/@AutophagyFa...
#IntermittentFasting #GutMicrobiome #MetabolicHealth
The hidden world inside you: How the gut microbiome shapes your health
Why your gut microbes are central to immunity, metabolism, and long-term health.
medium.com
December 16, 2025 at 11:31 AM
Your gut is a living ecosystem shaping immunity, metabolism, mood, and cognition. When you understand how food, stress, and daily habits shape your microbiome, you gain real agency over your health.
medium.com/@AutophagyFa...
#IntermittentFasting #GutMicrobiome #MetabolicHealth
medium.com/@AutophagyFa...
#IntermittentFasting #GutMicrobiome #MetabolicHealth
Shifts in gut microbes during IF track with changes in brain regions that govern appetite, impulse control, and emotional responses to food. It’s a glimpse into how tuning the microbiome could influence neural pathways and support long‑term weight regulation.
medium.com/@AutophagyFa...
#Obesity
medium.com/@AutophagyFa...
#Obesity
Rewiring the brain–gut–microbiome axis for weight loss
Insights from fMRI and metagenomic sequencing on how intermittent fasting remodels neural circuits and microbial communities to enhance…
medium.com
December 15, 2025 at 11:17 AM
Shifts in gut microbes during IF track with changes in brain regions that govern appetite, impulse control, and emotional responses to food. It’s a glimpse into how tuning the microbiome could influence neural pathways and support long‑term weight regulation.
medium.com/@AutophagyFa...
#Obesity
medium.com/@AutophagyFa...
#Obesity
Glucose isn’t the brain’s only fuel. Neurons tap lipid droplets during activity, while ketones from fasting provide a complementary energy pathway. This broader bioenergetic view reshapes how we think about aging, neurodegeneration, and brain resilience.
medium.com/@AutophagyFa...
#Neurons #Brain
medium.com/@AutophagyFa...
#Neurons #Brain
Beyond glucose: Lipids and ketones as precision fuel for the brain
Challenging the long-held dogma that glucose is the sole source of energy.
medium.com
December 3, 2025 at 1:04 PM
Glucose isn’t the brain’s only fuel. Neurons tap lipid droplets during activity, while ketones from fasting provide a complementary energy pathway. This broader bioenergetic view reshapes how we think about aging, neurodegeneration, and brain resilience.
medium.com/@AutophagyFa...
#Neurons #Brain
medium.com/@AutophagyFa...
#Neurons #Brain
When we obsess over numbers, we reduce food to a transactional exchange: input vs output, guilt vs reward. But when we shift the lens to quality, everything changes. Suddenly, food becomes a tool for repair, resilience, and regeneration.
#IntuitiveEating #HealthyEating #HealhyFood
#IntuitiveEating #HealthyEating #HealhyFood
November 28, 2025 at 3:33 PM
When we obsess over numbers, we reduce food to a transactional exchange: input vs output, guilt vs reward. But when we shift the lens to quality, everything changes. Suddenly, food becomes a tool for repair, resilience, and regeneration.
#IntuitiveEating #HealthyEating #HealhyFood
#IntuitiveEating #HealthyEating #HealhyFood
What we often label as “cravings” can, in truth, be symptoms of withdrawal from junk food. These substances hijack reward pathways, conditioning the brain to expect repeated hits. When we interrupt that loop, the discomfort isn’t genuine hunger. It’s the body recalibrating from a toxic dependency.
November 28, 2025 at 3:31 PM
What we often label as “cravings” can, in truth, be symptoms of withdrawal from junk food. These substances hijack reward pathways, conditioning the brain to expect repeated hits. When we interrupt that loop, the discomfort isn’t genuine hunger. It’s the body recalibrating from a toxic dependency.
Lab reference ranges are statistical averages—not indicators of peak function. So if your labs say “normal” but you feel tired, foggy, inflamed, or wired but exhausted, trust that signal. Your symptoms reflect how your system is adapting—or failing to adapt—to daily inputs.
#MetabolicHealth
#MetabolicHealth
November 27, 2025 at 9:37 AM
Lab reference ranges are statistical averages—not indicators of peak function. So if your labs say “normal” but you feel tired, foggy, inflamed, or wired but exhausted, trust that signal. Your symptoms reflect how your system is adapting—or failing to adapt—to daily inputs.
#MetabolicHealth
#MetabolicHealth
When mitochondrial function falters, damaged cells persist, inflammation persists, and chronic diseases develop. It can lead to problems like cancer (where bad cells don’t die) or neurodegenerative diseases (where good cells die too soon).
medium.com/@AutophagyFa...
#Mitophagy #Autophagy
medium.com/@AutophagyFa...
#Mitophagy #Autophagy
Prune with precision: Fasting empowers mitochondrial health by orchestrating apoptosis
Beyond energy: Mitochondria as cellular gatekeepers.
medium.com
November 27, 2025 at 9:25 AM
When mitochondrial function falters, damaged cells persist, inflammation persists, and chronic diseases develop. It can lead to problems like cancer (where bad cells don’t die) or neurodegenerative diseases (where good cells die too soon).
medium.com/@AutophagyFa...
#Mitophagy #Autophagy
medium.com/@AutophagyFa...
#Mitophagy #Autophagy
Modern eating patterns have fractured a core biological rhythm — sacrificing deep cellular repair for a perpetual state of metabolic engagement. Autophagy is a foundational pillar of cellular resilience, activated not by abundance but by intentional scarcity.
medium.com/@AutophagyFa...
#Autophagy
medium.com/@AutophagyFa...
#Autophagy
Understanding Autophagy: Precision cellular recycling
Cellular renewal through self-digestion.
medium.com
November 26, 2025 at 10:54 AM
Modern eating patterns have fractured a core biological rhythm — sacrificing deep cellular repair for a perpetual state of metabolic engagement. Autophagy is a foundational pillar of cellular resilience, activated not by abundance but by intentional scarcity.
medium.com/@AutophagyFa...
#Autophagy
medium.com/@AutophagyFa...
#Autophagy
Cravings aren’t random—brain reward circuits, hormones, and gut-brain signals shape them. Stress, poor sleep, and hyperpalatable foods amplify them. The goal isn’t to “fight” cravings but to reduce their intensity—through balanced meals, better sleep, and less stress. Reframe cravings as cues.
November 26, 2025 at 9:06 AM
Cravings aren’t random—brain reward circuits, hormones, and gut-brain signals shape them. Stress, poor sleep, and hyperpalatable foods amplify them. The goal isn’t to “fight” cravings but to reduce their intensity—through balanced meals, better sleep, and less stress. Reframe cravings as cues.
Lifestyle conditions are thought to build neurological reserve, resilience, and resistance — assets that help individuals remain neurocognitively healthy as they age. It's essential to be physically involved, cognitively engaged, socially connected, and creatively active as much as possible.
November 26, 2025 at 8:31 AM
Lifestyle conditions are thought to build neurological reserve, resilience, and resistance — assets that help individuals remain neurocognitively healthy as they age. It's essential to be physically involved, cognitively engaged, socially connected, and creatively active as much as possible.
While convenience often dictates dietary choices, evidence mounts linking UPFs to obesity and chronic disease. Their unchecked rise presents a profound public health challenge—one that demands both individual awareness and systemic change.
medium.com/@AutophagyFa...
#UltraProcessedFoods
medium.com/@AutophagyFa...
#UltraProcessedFoods
Engineered to hook, designed to harm: The ultra-processed food crisis
Convenience at the cost of health.
medium.com
November 20, 2025 at 1:38 PM
While convenience often dictates dietary choices, evidence mounts linking UPFs to obesity and chronic disease. Their unchecked rise presents a profound public health challenge—one that demands both individual awareness and systemic change.
medium.com/@AutophagyFa...
#UltraProcessedFoods
medium.com/@AutophagyFa...
#UltraProcessedFoods
Three meals a day? Cultural. Not biological.
Our biology is tuned to scarcity. Humans evolved through feast–fast cycles.
Intermittent fasting activates deep metabolic repair:
⒈ Better insulin sensitivity
⒉ Autophagy
⒊ Mitochondrial resilience
⒋ Lower inflammation
#IntermittentFasting
Our biology is tuned to scarcity. Humans evolved through feast–fast cycles.
Intermittent fasting activates deep metabolic repair:
⒈ Better insulin sensitivity
⒉ Autophagy
⒊ Mitochondrial resilience
⒋ Lower inflammation
#IntermittentFasting
November 20, 2025 at 11:08 AM
Three meals a day? Cultural. Not biological.
Our biology is tuned to scarcity. Humans evolved through feast–fast cycles.
Intermittent fasting activates deep metabolic repair:
⒈ Better insulin sensitivity
⒉ Autophagy
⒊ Mitochondrial resilience
⒋ Lower inflammation
#IntermittentFasting
Our biology is tuned to scarcity. Humans evolved through feast–fast cycles.
Intermittent fasting activates deep metabolic repair:
⒈ Better insulin sensitivity
⒉ Autophagy
⒊ Mitochondrial resilience
⒋ Lower inflammation
#IntermittentFasting
Intermittent fasting enhances lifespan and healthspan by boosting stress‑response pathways, metabolic flexibility, and autophagy. It improves insulin sensitivity, supports mitochondria, and reduces inflammation—building resilience against chronic diseases.
#IntermittentFasting #Aging #Healthspan
#IntermittentFasting #Aging #Healthspan
November 19, 2025 at 11:30 AM
Intermittent fasting enhances lifespan and healthspan by boosting stress‑response pathways, metabolic flexibility, and autophagy. It improves insulin sensitivity, supports mitochondria, and reduces inflammation—building resilience against chronic diseases.
#IntermittentFasting #Aging #Healthspan
#IntermittentFasting #Aging #Healthspan
Aging isn’t just about counting birthdays—it’s about the silent choreography inside our cells. In this article, I explore how science is reframing aging biology, and why understanding these cellular levers could empower us to shape longevity from the inside out.
medium.com/@AutophagyFa...
#Aging
medium.com/@AutophagyFa...
#Aging
Biology of aging: Cellular pathways that shape lifespan and healthspan
Intermittent fasting as a metabolic reset to restore resilience.
medium.com
November 19, 2025 at 10:15 AM
Aging isn’t just about counting birthdays—it’s about the silent choreography inside our cells. In this article, I explore how science is reframing aging biology, and why understanding these cellular levers could empower us to shape longevity from the inside out.
medium.com/@AutophagyFa...
#Aging
medium.com/@AutophagyFa...
#Aging