Ann Z. Bauer Sc.D.
@autismepi.bsky.social
Epidemiologist-Child Health, Neurological Development. “Outlier”. Covid & Long Covid investigator. Show me the evidence.
Action needed on Plastic additives linked sperm count decline
August 25, 2025 at 3:42 PM
Action needed on Plastic additives linked sperm count decline
Please be cautious with use of #Tylenol (acetaminophen, paracetamol) if you are trying to get pregnant.
Research published today indicates that acetaminophen could contribute to early embryonic loss (miscarriage) by impairing initial cell divisions.
pubmed.ncbi.nlm.nih.gov/40819833/
Research published today indicates that acetaminophen could contribute to early embryonic loss (miscarriage) by impairing initial cell divisions.
pubmed.ncbi.nlm.nih.gov/40819833/
August 18, 2025 at 11:04 AM
Please be cautious with use of #Tylenol (acetaminophen, paracetamol) if you are trying to get pregnant.
Research published today indicates that acetaminophen could contribute to early embryonic loss (miscarriage) by impairing initial cell divisions.
pubmed.ncbi.nlm.nih.gov/40819833/
Research published today indicates that acetaminophen could contribute to early embryonic loss (miscarriage) by impairing initial cell divisions.
pubmed.ncbi.nlm.nih.gov/40819833/
How is the U.S. doing?
May 9, 2025 at 11:52 PM
How is the U.S. doing?
New review conducted by @JnJ’s Kenvue.
They created Kenvue to shield their assets from #acetaminophen litigants.
Quantitative weight-of-evidence review of preclinical studies examining the potential developmental & reproduction toxicity of acetaminophen pubmed.ncbi.nlm.nih.gov/39982149/
They created Kenvue to shield their assets from #acetaminophen litigants.
Quantitative weight-of-evidence review of preclinical studies examining the potential developmental & reproduction toxicity of acetaminophen pubmed.ncbi.nlm.nih.gov/39982149/
February 23, 2025 at 5:09 AM
New review conducted by @JnJ’s Kenvue.
They created Kenvue to shield their assets from #acetaminophen litigants.
Quantitative weight-of-evidence review of preclinical studies examining the potential developmental & reproduction toxicity of acetaminophen pubmed.ncbi.nlm.nih.gov/39982149/
They created Kenvue to shield their assets from #acetaminophen litigants.
Quantitative weight-of-evidence review of preclinical studies examining the potential developmental & reproduction toxicity of acetaminophen pubmed.ncbi.nlm.nih.gov/39982149/
The evidence from both human & animal studies continues to mount that suggests the use of #acetaminophen increases risk of #autism, #ADHD & #asthma.
Funding is needed for definitive research.
Precautionary warning labels about pregnancy use are warranted.
pubmed.ncbi.nlm.nih.gov/34556849/
Funding is needed for definitive research.
Precautionary warning labels about pregnancy use are warranted.
pubmed.ncbi.nlm.nih.gov/34556849/
February 5, 2025 at 7:34 PM
The evidence from both human & animal studies continues to mount that suggests the use of #acetaminophen increases risk of #autism, #ADHD & #asthma.
Funding is needed for definitive research.
Precautionary warning labels about pregnancy use are warranted.
pubmed.ncbi.nlm.nih.gov/34556849/
Funding is needed for definitive research.
Precautionary warning labels about pregnancy use are warranted.
pubmed.ncbi.nlm.nih.gov/34556849/
What does the research tell us about what is causing #autism?
Genetics play a large role but environmental factors that may interact with genetic vulnerabilities have been identified.
Environmental factors include valproate (anti-epileptic med), acetaminophen & air pollution.
Genetics play a large role but environmental factors that may interact with genetic vulnerabilities have been identified.
Environmental factors include valproate (anti-epileptic med), acetaminophen & air pollution.
February 5, 2025 at 7:27 PM
What does the research tell us about what is causing #autism?
Genetics play a large role but environmental factors that may interact with genetic vulnerabilities have been identified.
Environmental factors include valproate (anti-epileptic med), acetaminophen & air pollution.
Genetics play a large role but environmental factors that may interact with genetic vulnerabilities have been identified.
Environmental factors include valproate (anti-epileptic med), acetaminophen & air pollution.
Recording and slides available:
Autism’s Rising Rates: A Deep Dive Into 50 Years of Data
Jill Escher, Escher Fund for Autism
Walter Zahorodny, PhD, Rutgers University
Register ncsautism.org/webinars
Autism’s Rising Rates: A Deep Dive Into 50 Years of Data
Jill Escher, Escher Fund for Autism
Walter Zahorodny, PhD, Rutgers University
Register ncsautism.org/webinars
January 4, 2025 at 10:24 PM
Recording and slides available:
Autism’s Rising Rates: A Deep Dive Into 50 Years of Data
Jill Escher, Escher Fund for Autism
Walter Zahorodny, PhD, Rutgers University
Register ncsautism.org/webinars
Autism’s Rising Rates: A Deep Dive Into 50 Years of Data
Jill Escher, Escher Fund for Autism
Walter Zahorodny, PhD, Rutgers University
Register ncsautism.org/webinars
If #acetaminophen exposure is like air pollution & #autism risk is greatest during the 2nd year, it could explain the regression observed by parents & why they continue to blame vaccines-despite the evidence.
Infant #Tylenol needs investigation ASAP given this:
pubmed.ncbi.nlm.nih.gov/35989852/
Infant #Tylenol needs investigation ASAP given this:
pubmed.ncbi.nlm.nih.gov/35989852/
December 30, 2024 at 4:54 PM
If #acetaminophen exposure is like air pollution & #autism risk is greatest during the 2nd year, it could explain the regression observed by parents & why they continue to blame vaccines-despite the evidence.
Infant #Tylenol needs investigation ASAP given this:
pubmed.ncbi.nlm.nih.gov/35989852/
Infant #Tylenol needs investigation ASAP given this:
pubmed.ncbi.nlm.nih.gov/35989852/
Preconception & gestational versus postnatal exposure to air pollutants & risk of #autism pubmed.ncbi.nlm.nih.gov/39676091/
Exposure during preconception exhibited a protective trend, while postnatal exposure, particularly during the 2nd yr of life uncovered substantially higher ASD risk
Exposure during preconception exhibited a protective trend, while postnatal exposure, particularly during the 2nd yr of life uncovered substantially higher ASD risk
December 30, 2024 at 4:16 PM
Preconception & gestational versus postnatal exposure to air pollutants & risk of #autism pubmed.ncbi.nlm.nih.gov/39676091/
Exposure during preconception exhibited a protective trend, while postnatal exposure, particularly during the 2nd yr of life uncovered substantially higher ASD risk
Exposure during preconception exhibited a protective trend, while postnatal exposure, particularly during the 2nd yr of life uncovered substantially higher ASD risk
Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders. pubmed.ncbi.nlm.nih.gov/37599994/
Suggests that neurodevelopmental disorder genetic etiology may be partially driven by a contribution of environment-induced germ line & somatic mutations.
Suggests that neurodevelopmental disorder genetic etiology may be partially driven by a contribution of environment-induced germ line & somatic mutations.
December 30, 2024 at 8:21 AM
Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders. pubmed.ncbi.nlm.nih.gov/37599994/
Suggests that neurodevelopmental disorder genetic etiology may be partially driven by a contribution of environment-induced germ line & somatic mutations.
Suggests that neurodevelopmental disorder genetic etiology may be partially driven by a contribution of environment-induced germ line & somatic mutations.
Keep in mind there are numerous studies which suggest #acetaminophen use during pregnancy increases #autism & #adhd risk.
#Tylenol is often used to relieve #Covid symptoms.
pubmed.ncbi.nlm.nih.gov/35989852/
#Tylenol is often used to relieve #Covid symptoms.
pubmed.ncbi.nlm.nih.gov/35989852/
December 28, 2024 at 4:38 PM
Keep in mind there are numerous studies which suggest #acetaminophen use during pregnancy increases #autism & #adhd risk.
#Tylenol is often used to relieve #Covid symptoms.
pubmed.ncbi.nlm.nih.gov/35989852/
#Tylenol is often used to relieve #Covid symptoms.
pubmed.ncbi.nlm.nih.gov/35989852/
Are these immune disorders just like #autism with the increased prevalence just due to genetics, better diagnosis and more awareness?
Or is there something that has changed in our #environment?
Genetics do not change this fast.
Or is there something that has changed in our #environment?
Genetics do not change this fast.
December 23, 2024 at 3:10 PM
Are these immune disorders just like #autism with the increased prevalence just due to genetics, better diagnosis and more awareness?
Or is there something that has changed in our #environment?
Genetics do not change this fast.
Or is there something that has changed in our #environment?
Genetics do not change this fast.
Between RFK Jr and Elon Musk, behold the new Tesla Cyberlung
December 14, 2024 at 9:15 PM
Between RFK Jr and Elon Musk, behold the new Tesla Cyberlung
Between RFK Jr and Elon Musk, behold the new Tesla Cyberlung
December 14, 2024 at 9:11 PM
Between RFK Jr and Elon Musk, behold the new Tesla Cyberlung
Self-medication among pregnant women vs. the general population
pubmed.ncbi.nlm.nih.gov/39669310/
#Acetaminophen was the most used medication.
Pregnant women should carefully follow their drs’ advice before initiating self-medication to avoid preventable maternal & fetal adverse effects.
pubmed.ncbi.nlm.nih.gov/39669310/
#Acetaminophen was the most used medication.
Pregnant women should carefully follow their drs’ advice before initiating self-medication to avoid preventable maternal & fetal adverse effects.
December 14, 2024 at 7:53 PM
Self-medication among pregnant women vs. the general population
pubmed.ncbi.nlm.nih.gov/39669310/
#Acetaminophen was the most used medication.
Pregnant women should carefully follow their drs’ advice before initiating self-medication to avoid preventable maternal & fetal adverse effects.
pubmed.ncbi.nlm.nih.gov/39669310/
#Acetaminophen was the most used medication.
Pregnant women should carefully follow their drs’ advice before initiating self-medication to avoid preventable maternal & fetal adverse effects.
Loss of skills/#Autism regression, observed by parents near vaccination time, is why many continue to think vaccines are the culprit.
Might there be another explanation?
Infant #Acetaminophen (#Tylenol) use needs investigation
pubmed.ncbi.nlm.nih.gov/35989852/
pubmed.ncbi.nlm.nih.gov/18445737/
Might there be another explanation?
Infant #Acetaminophen (#Tylenol) use needs investigation
pubmed.ncbi.nlm.nih.gov/35989852/
pubmed.ncbi.nlm.nih.gov/18445737/
December 10, 2024 at 9:03 AM
Loss of skills/#Autism regression, observed by parents near vaccination time, is why many continue to think vaccines are the culprit.
Might there be another explanation?
Infant #Acetaminophen (#Tylenol) use needs investigation
pubmed.ncbi.nlm.nih.gov/35989852/
pubmed.ncbi.nlm.nih.gov/18445737/
Might there be another explanation?
Infant #Acetaminophen (#Tylenol) use needs investigation
pubmed.ncbi.nlm.nih.gov/35989852/
pubmed.ncbi.nlm.nih.gov/18445737/
Multi-omics approach reveals dysregulated genes during human embryonic stem cell neuronal differentiation exposure to paracetamol (#acetaminophen) pubmed.ncbi.nlm.nih.gov/37731623/
“paracetamol may play a causal role in impaired neurodevelopment.”
Experimental studies important too.
“paracetamol may play a causal role in impaired neurodevelopment.”
Experimental studies important too.
December 6, 2024 at 4:19 PM
Multi-omics approach reveals dysregulated genes during human embryonic stem cell neuronal differentiation exposure to paracetamol (#acetaminophen) pubmed.ncbi.nlm.nih.gov/37731623/
“paracetamol may play a causal role in impaired neurodevelopment.”
Experimental studies important too.
“paracetamol may play a causal role in impaired neurodevelopment.”
Experimental studies important too.
Gestational paracetamol (#acetaminophen) exposure induces core behaviors of neurodevelopmental disorders in infant rats & modifies response to a cannabinoid agonist in rats
pubmed.ncbi.nlm.nih.gov/37391024/
Experimental evidence is not susceptible to same biases as epidemiology.
pubmed.ncbi.nlm.nih.gov/37391024/
Experimental evidence is not susceptible to same biases as epidemiology.
December 6, 2024 at 4:15 PM
Gestational paracetamol (#acetaminophen) exposure induces core behaviors of neurodevelopmental disorders in infant rats & modifies response to a cannabinoid agonist in rats
pubmed.ncbi.nlm.nih.gov/37391024/
Experimental evidence is not susceptible to same biases as epidemiology.
pubmed.ncbi.nlm.nih.gov/37391024/
Experimental evidence is not susceptible to same biases as epidemiology.
Sex-specific neurobehavioral & prefrontal cortex gene expression alterations following developmental #acetaminophen exposure in mice pubmed.ncbi.nlm.nih.gov/36549432/
Additional evidence for the neurodevelopmental harm of prenatal acetaminophen exposure.
Experimental evidence important too.
Additional evidence for the neurodevelopmental harm of prenatal acetaminophen exposure.
Experimental evidence important too.
December 6, 2024 at 4:13 PM
Sex-specific neurobehavioral & prefrontal cortex gene expression alterations following developmental #acetaminophen exposure in mice pubmed.ncbi.nlm.nih.gov/36549432/
Additional evidence for the neurodevelopmental harm of prenatal acetaminophen exposure.
Experimental evidence important too.
Additional evidence for the neurodevelopmental harm of prenatal acetaminophen exposure.
Experimental evidence important too.
Paracetamol (#acetaminophen) perturbs neuronal arborization & disrupts the cytoskeletal proteins SPTBN1 & TUBB3 in both human & chicken in vitro models
pubmed.ncbi.nlm.nih.gov/35714712
These protein levels are important in neuronal structure & function
pubmed.ncbi.nlm.nih.gov/35714712
These protein levels are important in neuronal structure & function
December 6, 2024 at 4:11 PM
Paracetamol (#acetaminophen) perturbs neuronal arborization & disrupts the cytoskeletal proteins SPTBN1 & TUBB3 in both human & chicken in vitro models
pubmed.ncbi.nlm.nih.gov/35714712
These protein levels are important in neuronal structure & function
pubmed.ncbi.nlm.nih.gov/35714712
These protein levels are important in neuronal structure & function
Gestational exposure to paracetamol (#acetaminophen) in rats induces neurofunctional alterations in the progeny.
pubmed.ncbi.nlm.nih.gov/31644948/
Experimental evidence, not just epidemiology, is important for making a causal determination.
pubmed.ncbi.nlm.nih.gov/31644948/
Experimental evidence, not just epidemiology, is important for making a causal determination.
December 6, 2024 at 4:05 PM
Gestational exposure to paracetamol (#acetaminophen) in rats induces neurofunctional alterations in the progeny.
pubmed.ncbi.nlm.nih.gov/31644948/
Experimental evidence, not just epidemiology, is important for making a causal determination.
pubmed.ncbi.nlm.nih.gov/31644948/
Experimental evidence, not just epidemiology, is important for making a causal determination.
Adult neurobehavioral alterations in male & female mice following developmental exposure to paracetamol (#acetaminophen)
pubmed.ncbi.nlm.nih.gov/28448685/
Neurodevelopmental time points correspond to the beginning of 3rd trimester & time around birth in humans, supporting existing human data.
pubmed.ncbi.nlm.nih.gov/28448685/
Neurodevelopmental time points correspond to the beginning of 3rd trimester & time around birth in humans, supporting existing human data.
December 6, 2024 at 3:56 PM
Adult neurobehavioral alterations in male & female mice following developmental exposure to paracetamol (#acetaminophen)
pubmed.ncbi.nlm.nih.gov/28448685/
Neurodevelopmental time points correspond to the beginning of 3rd trimester & time around birth in humans, supporting existing human data.
pubmed.ncbi.nlm.nih.gov/28448685/
Neurodevelopmental time points correspond to the beginning of 3rd trimester & time around birth in humans, supporting existing human data.
Neurodevelopmental or behavioral disorders in children conceived after assisted reproductive technologies: a nationwide cohort study
pubmed.ncbi.nlm.nih.gov/39426700/
Finds little evidence for increased risk of neurodevelopmental or behavioral disorders.
#autism #adhd #IVF
pubmed.ncbi.nlm.nih.gov/39426700/
Finds little evidence for increased risk of neurodevelopmental or behavioral disorders.
#autism #adhd #IVF
November 19, 2024 at 5:32 PM
Neurodevelopmental or behavioral disorders in children conceived after assisted reproductive technologies: a nationwide cohort study
pubmed.ncbi.nlm.nih.gov/39426700/
Finds little evidence for increased risk of neurodevelopmental or behavioral disorders.
#autism #adhd #IVF
pubmed.ncbi.nlm.nih.gov/39426700/
Finds little evidence for increased risk of neurodevelopmental or behavioral disorders.
#autism #adhd #IVF
Impaired brainstem auditory processing evoked after in utero exposure to high dose paracetamol (#acetaminophen, #Tylenol) exposure in rats. pubmed.ncbi.nlm.nih.gov/39550993/
Audio processing deficits are a common feature of #autism spectrum disorder.
Audio processing deficits are a common feature of #autism spectrum disorder.
November 18, 2024 at 2:55 PM
Impaired brainstem auditory processing evoked after in utero exposure to high dose paracetamol (#acetaminophen, #Tylenol) exposure in rats. pubmed.ncbi.nlm.nih.gov/39550993/
Audio processing deficits are a common feature of #autism spectrum disorder.
Audio processing deficits are a common feature of #autism spectrum disorder.