Austin Morrissey
Austin Morrissey
@austinpatrick.bsky.social
mRNA is cool
When experiments don't yield expected results, remembering who we serve restores focus and purpose. Setting oneself to research while keeping the end goal in mind serves to spur mental engagement, in turn, the attitude towards work becomes imbued with a greater sense of meaning.
August 31, 2025 at 12:22 AM
@mehdirhasan.bsky.social that debate was unhinged, well done on exposing that these harmful ideologies are sprouting in America
July 21, 2025 at 3:43 AM
@worrydream.com I came across your work when looking for ways to make my tech workflow more accessible, so excited to starting making my way through your corpus
June 2, 2025 at 10:34 PM
Calciphylaxis is a deadly disease, marked by skin necrosis and high mortality. It has no cure. Its pathogenesis has remained poorly understood. We identify a self-amplifying, destructive loop that is druggable with existing therapies Human trials are now needed.

We share these findings in Science
Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis
Microvascular thrombi in calciphylaxis skin can be pharmacologically targeted by anti–IL-6 therapies.
www.science.org
May 28, 2025 at 2:25 AM
where is the best place to do a PHD geared towards RNA therapeutics given the state of research in the US?
May 6, 2025 at 1:28 AM
"....Weissman was speaking about sickle cell anemia, a disease that disproportionately affects regions lacking the capital for curative research. Within his dream is a vision: a future where state-of-the-art medicine reaches those who need it most, wherever they are."
April 25, 2025 at 9:19 AM
When we discuss diversity in scientific settings, we often focus on visible cultural differences. Recognizing such is essential to work in a multicultural workplace. To work effectively together, collaboration is needed; mutual respect is required.

Here's why we need it.
Beyond Good Intentions: Diversity in Scientific Settings
It does more than you'd expect.
austinpatrick.substack.com
March 17, 2025 at 7:48 PM
Is research gate really the only online community for discussions on improving scientific technique?
March 12, 2025 at 5:25 PM
How is their no stack overflow equivalent for pharma / life science research? Results get published, as do methods, but it seems so much meta knowledge on problem solving in assays is locked up within people.
February 26, 2025 at 1:09 AM
Google's AI co-scientist, unveiled yesterday, demonstrates immediate real-world impact in accelerating biomedical research. The system has already shown promising real-world results in three biomedical applications:
February 20, 2025 at 11:33 PM
What in vitro assays have the most carryover for general drug discovery programs?
February 4, 2025 at 10:53 PM
Drawing on Anthropic's research on deceptive LLMs, I argue that O3's safety testing for CBRN risks may be inadequate.

open.substack.com/pub/austinpa...

#Anthropic #AISafety #AIRisk
Deepseek, OpenAI's O3, and the Art of Cold War
What Russian sleeper agents teach us about artificial intelligence safety
open.substack.com
February 3, 2025 at 11:19 PM