Atishay Jay
@atishayjay.bsky.social
Bioengineering PhD student at UPenn
Reposted by Atishay Jay
ft. @yeqiaoz.bsky.social, N. Burget, Tobias Friedrich, @faryabi.bsky.social (@pennpathlabmed.bsky.social), @atishayjay.bsky.social (Bioeng), S. Yoon & @vahedilab.bsky.social (@penngenetics.bsky.social) @pennepigenetics.bsky.social @i3h-upenn.bsky.social www.nature.com/articles/s41...
December 19, 2025 at 7:33 PM
ft. @yeqiaoz.bsky.social, N. Burget, Tobias Friedrich, @faryabi.bsky.social (@pennpathlabmed.bsky.social), @atishayjay.bsky.social (Bioeng), S. Yoon & @vahedilab.bsky.social (@penngenetics.bsky.social) @pennepigenetics.bsky.social @i3h-upenn.bsky.social www.nature.com/articles/s41...
Reposted by Atishay Jay
ft. M. Abedi, P. Rai, Y. Zhou, C. Liu, I. Johnson, A. Chandra, M. Fasolino, S. Rostami, W. Wang, Z. Min, Y. Li, M. Yu, @atishayjay.bsky.social, V. Lian, M. Silverman, @kkaestner.bsky.social, A. Naji, B. Faryabi & @vahedilab.bsky.social @penngenetics.bsky.social www.science.org/doi/10.1126/...
December 10, 2025 at 3:47 PM
ft. M. Abedi, P. Rai, Y. Zhou, C. Liu, I. Johnson, A. Chandra, M. Fasolino, S. Rostami, W. Wang, Z. Min, Y. Li, M. Yu, @atishayjay.bsky.social, V. Lian, M. Silverman, @kkaestner.bsky.social, A. Naji, B. Faryabi & @vahedilab.bsky.social @penngenetics.bsky.social www.science.org/doi/10.1126/...
Reposted by Atishay Jay
I am very excited to share our collaborative work on multiome profiling of gene expression and chromatin accessibility of more than 1 million immune cells in pancreatic lymph nodes and spleens in human type 1 diabetes in
@sciimmunology.bsky.social scim.ag/4o12TOZ
@sciimmunology.bsky.social scim.ag/4o12TOZ
Joint profiling of gene expression and chromatin accessibility in pancreatic lymph nodes and spleens in human type 1 diabetes
Joint chromatin accessibility and transcriptomic profiling of human and mouse pancreatic lymph nodes uncovers distinct features of CD4 T cells in T1D.
scim.ag
November 26, 2025 at 6:55 PM
I am very excited to share our collaborative work on multiome profiling of gene expression and chromatin accessibility of more than 1 million immune cells in pancreatic lymph nodes and spleens in human type 1 diabetes in
@sciimmunology.bsky.social scim.ag/4o12TOZ
@sciimmunology.bsky.social scim.ag/4o12TOZ
Reposted by Atishay Jay
Lineage-determining transcription factors (EBF1 TCF1) radially position enhancers within gene loci to enable multi-enhancer regulation of key oncogenes @ single-allele level @natcellbio.nature.com @pennmedicine.bsky.social @atishayjay.bsky.social @vahedilab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 4, 2025 at 2:34 AM
Lineage-determining transcription factors (EBF1 TCF1) radially position enhancers within gene loci to enable multi-enhancer regulation of key oncogenes @ single-allele level @natcellbio.nature.com @pennmedicine.bsky.social @atishayjay.bsky.social @vahedilab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Atishay Jay
Beyond excited to share the collaborative work with @faryabi.bsky.social led by stars Yeqiao Zhou and @atishayjay.bsky.social; Walking along thousands of chromosomes has shown us just how essential it is to measure chromatin fiber geometry to truly understand enhancer biology. tinyurl.com/2st3afwf
Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation - Nature Cell Biology
Zhou, Jay et al. report that in mantle cell lymphoma and T cell leukaemia, lineage-determining transcription factors share a mechanism to regulate how multiple enhancers control oncogene expression th...
www.nature.com
December 2, 2025 at 3:57 PM
Beyond excited to share the collaborative work with @faryabi.bsky.social led by stars Yeqiao Zhou and @atishayjay.bsky.social; Walking along thousands of chromosomes has shown us just how essential it is to measure chromatin fiber geometry to truly understand enhancer biology. tinyurl.com/2st3afwf
Reposted by Atishay Jay
Three new manuscripts from Faryabi and Vahedi labs on chromatin folding, ORCA, oncogene regulation and T1D immunology. Individually great, collectively unstoppable. @faryabi.bsky.social @vahedilab.bsky.social @atishayjay.bsky.social
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
OLIVE provides rapid visualization and analysis of chromatin tracing experiments
Zhou et al. develop the optical looping interactive viewing engine (OLIVE), a web-based
application for browsing and exploring user-generated and publicly available chromatin
tracing datasets.
www.cell.com
December 2, 2025 at 5:30 PM
Three new manuscripts from Faryabi and Vahedi labs on chromatin folding, ORCA, oncogene regulation and T1D immunology. Individually great, collectively unstoppable. @faryabi.bsky.social @vahedilab.bsky.social @atishayjay.bsky.social
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
Reposted by Atishay Jay
🚨 New #preprint alert!
We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...
We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...
June 26, 2025 at 3:43 PM
🚨 New #preprint alert!
We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...
We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...
Reposted by Atishay Jay
Congrats to Atishay and Carlos for their review article on the epigenetics regulation of T cells: www.nature.com/articles/s41...
The epigenetic landscape of fate decisions in T cells - Nature Immunology
Vahedi and colleagues review the mechanisms shaping the epigenetic landscape of CD4+ and CD8+ T cells during development and differentiation.
www.nature.com
March 19, 2025 at 4:15 PM
Congrats to Atishay and Carlos for their review article on the epigenetics regulation of T cells: www.nature.com/articles/s41...