Spakowitz Lab
@aspakowitz.bsky.social
https://web.stanford.edu/~ajspakow/
polymer physics | biophysics | theory and simulation
Stanford University
polymer physics | biophysics | theory and simulation
Stanford University
Our recent manuscript “Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk” was published in PNAS. Joe Wakim used simulations and machine learning to reveal mechanisms for programming and reprogramming of cell behavior.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk | PNAS
The spatial organization of chromatin is governed by epigenetic factors, including
epigenetic marks and the reader proteins that bind them. By dict...
www.pnas.org
November 18, 2025 at 7:25 PM
Our recent manuscript “Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk” was published in PNAS. Joe Wakim used simulations and machine learning to reveal mechanisms for programming and reprogramming of cell behavior.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Thomas Habte and I recently published “Leveraging inhomogeneous binding of incompatible constituents for adaptive copolymer self-assembly” in Soft Matter, predicting a new co-polymer material that can access a range of stable phases without changing polymer sequence.
pubs.rsc.org/en/content/a...
pubs.rsc.org/en/content/a...
Leveraging inhomogeneous binding of incompatible constituents for adaptive copolymer self-assembly
Using a polymer field-theoretic model, we present a system containing copolymers and two distinct chemical moieties that bind heterogeneously along the copolymer chains, enabling self-assembly of a ra...
pubs.rsc.org
November 18, 2025 at 7:23 PM
Thomas Habte and I recently published “Leveraging inhomogeneous binding of incompatible constituents for adaptive copolymer self-assembly” in Soft Matter, predicting a new co-polymer material that can access a range of stable phases without changing polymer sequence.
pubs.rsc.org/en/content/a...
pubs.rsc.org/en/content/a...
The Spakowitz Lab at Stanford (Theory and Computation of Biological Processes and Soft Materials) is delighted to join the Bluesky community! We look forward to sharing our work and to learning about your research achievements.
November 17, 2025 at 5:33 PM
The Spakowitz Lab at Stanford (Theory and Computation of Biological Processes and Soft Materials) is delighted to join the Bluesky community! We look forward to sharing our work and to learning about your research achievements.