Ankit Sinha
@asinha-yyz.bsky.social
Mass spectrometrist and cancer biologist researching atherosclerosis through the lens of proteomics. Likes and requotes are messages I bookmark for future investigation. YYZ/MUC. 🇨🇦in🇩🇪
I appreciate the detailed reply. I agree & experimentally observed that convergence to the 1st moment (i.e. mean) leads to underestimating 2nd+ moments. Also, MICE was a little better at preserving the higher moments. I used the matrix norm of the covariance matrix to measure the imputation artefact
February 14, 2025 at 12:12 AM
I appreciate the detailed reply. I agree & experimentally observed that convergence to the 1st moment (i.e. mean) leads to underestimating 2nd+ moments. Also, MICE was a little better at preserving the higher moments. I used the matrix norm of the covariance matrix to measure the imputation artefact