Ashley Nielsen
@ashley-n-nielsen.bsky.social
Incoming Assistant Professor in Pediatric Neurology at Washington University in St. Louis
babies 👶🏼, fMRI 🧠, multivariate prediction 👩🏼💻, pre- & post-natal exposures🤰🏼, neuroplasticity ✨, mental health 🧘🏼♀️, higher education 👩🏼🏫
babies 👶🏼, fMRI 🧠, multivariate prediction 👩🏼💻, pre- & post-natal exposures🤰🏼, neuroplasticity ✨, mental health 🧘🏼♀️, higher education 👩🏼🏫
In line with what has been found in children/teens, reduced FC between the amygdala & mePFC at birth was associated with prenatal social disadvantage
Yet, this pattern was similar across subcortical structures potentially indicating a shared mechanism/vulnerability
Yet, this pattern was similar across subcortical structures potentially indicating a shared mechanism/vulnerability
December 2, 2024 at 11:26 PM
In line with what has been found in children/teens, reduced FC between the amygdala & mePFC at birth was associated with prenatal social disadvantage
Yet, this pattern was similar across subcortical structures potentially indicating a shared mechanism/vulnerability
Yet, this pattern was similar across subcortical structures potentially indicating a shared mechanism/vulnerability
Most all functional networks contained variation in FC that could be used to estimate prenatal exposure to social disadvantage
Late developing networks key to executive function & behavioral adaptation (ventral attention, dorsal attention, fronto parietal, & somatomotor) contained unique variation
Late developing networks key to executive function & behavioral adaptation (ventral attention, dorsal attention, fronto parietal, & somatomotor) contained unique variation
December 2, 2024 at 11:26 PM
Most all functional networks contained variation in FC that could be used to estimate prenatal exposure to social disadvantage
Late developing networks key to executive function & behavioral adaptation (ventral attention, dorsal attention, fronto parietal, & somatomotor) contained unique variation
Late developing networks key to executive function & behavioral adaptation (ventral attention, dorsal attention, fronto parietal, & somatomotor) contained unique variation
Multivariate predictive modeling revealed that neonatal functional connectivity varied as a function of prenatal exposure to social disadvantage (R=0.43, R^2=0.18), with validation in an independent sample (n=175)
December 2, 2024 at 11:26 PM
Multivariate predictive modeling revealed that neonatal functional connectivity varied as a function of prenatal exposure to social disadvantage (R=0.43, R^2=0.18), with validation in an independent sample (n=175)
New paper out today in PNAS 🎉 demonstrating:
1) an association between social disadvantage & child brain function can be observed as early as birth
2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity
doi.org/10.1073/pnas...
1) an association between social disadvantage & child brain function can be observed as early as birth
2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity
doi.org/10.1073/pnas...
December 2, 2024 at 11:26 PM
New paper out today in PNAS 🎉 demonstrating:
1) an association between social disadvantage & child brain function can be observed as early as birth
2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity
doi.org/10.1073/pnas...
1) an association between social disadvantage & child brain function can be observed as early as birth
2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity
doi.org/10.1073/pnas...