Arkana Labs
@arkanalabs.bsky.social
We're a center for renal & neuromuscular pathology focused on one thing: improving care for patients. #renal #pathsky #renalpath #neuropath #neuromuscular #kidneypath
Here is today’s #eyeSCANdy! Acellular scanning EM showing a glomerulus with a fibrocellular crescent (bottom).
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath #pathsky
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath #pathsky
November 20, 2025 at 2:01 PM
Here is today’s #eyeSCANdy! Acellular scanning EM showing a glomerulus with a fibrocellular crescent (bottom).
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath #pathsky
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath #pathsky
A sample from the pathology teaching slide set on Antineutrophil Cytoplasmic Antibody (ANCA)-associated (ANCA) Vasculitis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath #nephsky
#KDIGO #pathology #renal #kidneypath #nephsky
November 19, 2025 at 2:02 PM
A sample from the pathology teaching slide set on Antineutrophil Cytoplasmic Antibody (ANCA)-associated (ANCA) Vasculitis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath #nephsky
#KDIGO #pathology #renal #kidneypath #nephsky
(2/2) The new Banff 2017 Meeting report (see reference below) also places enhanced emphasis on the role of C4d staining (Fig. 2) in peritubular capillaries in the diagnosis of active ABMR – even in the absence of donor specific antibodies.
November 18, 2025 at 2:03 PM
(2/2) The new Banff 2017 Meeting report (see reference below) also places enhanced emphasis on the role of C4d staining (Fig. 2) in peritubular capillaries in the diagnosis of active ABMR – even in the absence of donor specific antibodies.
(1/2) The presence of peritubular capillaritis (see arrow Fig. 1) is an important component of microvascular inflammation, along with glomerulitis, in the diagnosis of active antibody-mediated rejection (ABMR).
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
November 18, 2025 at 2:03 PM
(1/2) The presence of peritubular capillaritis (see arrow Fig. 1) is an important component of microvascular inflammation, along with glomerulitis, in the diagnosis of active antibody-mediated rejection (ABMR).
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
What is your diagnosis for this finding in a young patient with renal artery stenosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
November 17, 2025 at 2:02 PM
What is your diagnosis for this finding in a young patient with renal artery stenosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
A case of acute tubular injury with both hemoglobin and myoglobin casts. This patient presented with AKI, hemolytic anemia and CK 8000 after being found down for an unknown period.
#kidneypath #pathology #nephsky #pathsky
#kidneypath #pathology #nephsky #pathsky
November 14, 2025 at 2:02 PM
A case of acute tubular injury with both hemoglobin and myoglobin casts. This patient presented with AKI, hemolytic anemia and CK 8000 after being found down for an unknown period.
#kidneypath #pathology #nephsky #pathsky
#kidneypath #pathology #nephsky #pathsky
Spotted by Dr. Singh! A KW nodule measuring 204.65 um in diameter in a case of diabetic nephropathy. #worlddiabetesmonth #renal #kidneypath #nephsky
November 13, 2025 at 2:02 PM
Spotted by Dr. Singh! A KW nodule measuring 204.65 um in diameter in a case of diabetic nephropathy. #worlddiabetesmonth #renal #kidneypath #nephsky
A sample from the pathology teaching slide set on Focal and Segmental Glomerulosclerosis in Adults, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath #nephsky
#KDIGO #pathology #renal #kidneypath #nephsky
November 12, 2025 at 2:02 PM
A sample from the pathology teaching slide set on Focal and Segmental Glomerulosclerosis in Adults, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath #nephsky
#KDIGO #pathology #renal #kidneypath #nephsky
3/ Most tophi are also associated with crystalline clefts formed by the deposition of monosodium urate (see arrow). Urate crystals are best seen in alcohol-fixed tissue or in frozen tissue sections, since most crystals dissolve after routine formalin fixation.
November 11, 2025 at 2:02 PM
3/ Most tophi are also associated with crystalline clefts formed by the deposition of monosodium urate (see arrow). Urate crystals are best seen in alcohol-fixed tissue or in frozen tissue sections, since most crystals dissolve after routine formalin fixation.
2/ Tophi frequently occur in the medulla, and usually consist of central regions of acellular, granular material surrounded by epithelioid macrophages, syncytial-type giant cells, and lymphocytes.
November 11, 2025 at 2:02 PM
2/ Tophi frequently occur in the medulla, and usually consist of central regions of acellular, granular material surrounded by epithelioid macrophages, syncytial-type giant cells, and lymphocytes.
1/ This biopsy shows the characteristic features of uric acid nephropathy (commonly known as gout), which results from precipitation of uric acid in the kidney parenchyma.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
November 11, 2025 at 2:02 PM
1/ This biopsy shows the characteristic features of uric acid nephropathy (commonly known as gout), which results from precipitation of uric acid in the kidney parenchyma.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
This image is from a biopsy of a young female who presented with proteinuria during pregnancy. Routine immunofluorescence was negative. What is this stain and what is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
November 10, 2025 at 1:50 PM
This image is from a biopsy of a young female who presented with proteinuria during pregnancy. Routine immunofluorescence was negative. What is this stain and what is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
This EM image shows powdery, punctate electron-dense deposits along the tubular basement membranes, characteristic of LCDD. These deposits lack the organized fibrillar structure seen in amyloidosis & appear as non-organized granular material.
#kidneypath #renal #nephsky #pathsky
#kidneypath #renal #nephsky #pathsky
November 7, 2025 at 2:18 PM
This EM image shows powdery, punctate electron-dense deposits along the tubular basement membranes, characteristic of LCDD. These deposits lack the organized fibrillar structure seen in amyloidosis & appear as non-organized granular material.
#kidneypath #renal #nephsky #pathsky
#kidneypath #renal #nephsky #pathsky
Improving biopsy adequacy is essential to improving patient care. Listen to the discussion @nephrosharma.bsky.social and @glombandit.bsky.social had with Dr. Salil Parikh to join the conversation around biopsy adequacy.
#nephsky #radiology
LISTEN NOW: https://www.youtube.com/watch?v=iNNWh9ZonXc
#nephsky #radiology
LISTEN NOW: https://www.youtube.com/watch?v=iNNWh9ZonXc
November 7, 2025 at 2:04 PM
Improving biopsy adequacy is essential to improving patient care. Listen to the discussion @nephrosharma.bsky.social and @glombandit.bsky.social had with Dr. Salil Parikh to join the conversation around biopsy adequacy.
#nephsky #radiology
LISTEN NOW: https://www.youtube.com/watch?v=iNNWh9ZonXc
#nephsky #radiology
LISTEN NOW: https://www.youtube.com/watch?v=iNNWh9ZonXc
How might nephrologists work with radiologists to improve biopsy adequacy and patient care?
#nephsky #radiology #renal
Listen to the conversation: youtu.be/iNNWh9ZonXc?...
#nephsky #radiology #renal
Listen to the conversation: youtu.be/iNNWh9ZonXc?...
November 6, 2025 at 4:17 PM
How might nephrologists work with radiologists to improve biopsy adequacy and patient care?
#nephsky #radiology #renal
Listen to the conversation: youtu.be/iNNWh9ZonXc?...
#nephsky #radiology #renal
Listen to the conversation: youtu.be/iNNWh9ZonXc?...
Here is today’s #eyeSCANdy! Acellular scanning EM showing variably sized discrete GBM perforations in segmental necrotizing and crescentic glomerulonephritis.
Photo courtesy of Dr. Stephen Bonsib. #renal #kidneypath #pathsky #nephsky
Photo courtesy of Dr. Stephen Bonsib. #renal #kidneypath #pathsky #nephsky
November 6, 2025 at 2:02 PM
Here is today’s #eyeSCANdy! Acellular scanning EM showing variably sized discrete GBM perforations in segmental necrotizing and crescentic glomerulonephritis.
Photo courtesy of Dr. Stephen Bonsib. #renal #kidneypath #pathsky #nephsky
Photo courtesy of Dr. Stephen Bonsib. #renal #kidneypath #pathsky #nephsky
@nephrosharma.bsky.social and @glombandit.bsky.social spoke to radiologist Dr. Salil Parikh about how his team achieves such high biopsy adequacy rates. #renal #nephsky #radiology
Listen to the full episode here: youtu.be/iNNWh9ZonXc?...
Listen to the full episode here: youtu.be/iNNWh9ZonXc?...
November 5, 2025 at 2:34 PM
@nephrosharma.bsky.social and @glombandit.bsky.social spoke to radiologist Dr. Salil Parikh about how his team achieves such high biopsy adequacy rates. #renal #nephsky #radiology
Listen to the full episode here: youtu.be/iNNWh9ZonXc?...
Listen to the full episode here: youtu.be/iNNWh9ZonXc?...
A sample from the pathology teaching slide set on Antineutrophil Cytoplasmic Antibody (ANCA)-Associated, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #renal #kidneypath #nephsky #pathsky
#KDIGO #renal #kidneypath #nephsky #pathsky
November 5, 2025 at 2:01 PM
A sample from the pathology teaching slide set on Antineutrophil Cytoplasmic Antibody (ANCA)-Associated, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #renal #kidneypath #nephsky #pathsky
#KDIGO #renal #kidneypath #nephsky #pathsky
If you're going to Kidney Week in Houston, don't forget to drop by booth 1925 to say hi to us!
@asnkidney.bsky.social #ASN #KidneyWk2025 #ASN2025
@asnkidney.bsky.social #ASN #KidneyWk2025 #ASN2025
November 4, 2025 at 9:55 PM
If you're going to Kidney Week in Houston, don't forget to drop by booth 1925 to say hi to us!
@asnkidney.bsky.social #ASN #KidneyWk2025 #ASN2025
@asnkidney.bsky.social #ASN #KidneyWk2025 #ASN2025
2/ In contrast, Fig. 2 shows a biopsy from a patient with acute tubular injury in which there is prominent luminal ectasia and loss of brush border PAS staining. Other features seen in acute tubular injury include tubular epithelial cell vacuolization, nucleolar enlargement, and mitotic activity.
November 4, 2025 at 2:03 PM
2/ In contrast, Fig. 2 shows a biopsy from a patient with acute tubular injury in which there is prominent luminal ectasia and loss of brush border PAS staining. Other features seen in acute tubular injury include tubular epithelial cell vacuolization, nucleolar enlargement, and mitotic activity.
1/ What does acute tubular injury (ATI) look like in a kidney biopsy? For comparison, Fig. 1 shows a biopsy with a normal appearing tubulointerstitium. The tubules show a back-to-back configuration, and the proximal tubular PAS-positive brush borders are easily identified.
#renal #nephsky #pathsky
#renal #nephsky #pathsky
November 4, 2025 at 2:03 PM
If you're attending #ASN this week, stop by Arkana's booth (#1925) for a free renal biopsy adequacy spinner that can give you guidance on adequacy standards. #nephrology #kidneyweek
November 3, 2025 at 6:46 PM
If you're attending #ASN this week, stop by Arkana's booth (#1925) for a free renal biopsy adequacy spinner that can give you guidance on adequacy standards. #nephrology #kidneyweek
(1/3) This 40-year-old patient underwent sural nerve biopsy to evaluate for a painful mixed large fiber and small fiber axonal neuropathy. The biopsy showed light microscopic features of a chronic active axonopathic process.
#NeuroNotes #neuropath #pathology #neuromuscularpath
#NeuroNotes #neuropath #pathology #neuromuscularpath
November 3, 2025 at 2:30 PM
(1/3) This 40-year-old patient underwent sural nerve biopsy to evaluate for a painful mixed large fiber and small fiber axonal neuropathy. The biopsy showed light microscopic features of a chronic active axonopathic process.
#NeuroNotes #neuropath #pathology #neuromuscularpath
#NeuroNotes #neuropath #pathology #neuromuscularpath
What is your diagnosis in a 35 y/o male with paraplegia and chronic osteomyelitis who presents with nephrotic syndrome? Bonus: What subtype would you suspect based on the clinical history?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
November 3, 2025 at 2:02 PM
What is your diagnosis in a 35 y/o male with paraplegia and chronic osteomyelitis who presents with nephrotic syndrome? Bonus: What subtype would you suspect based on the clinical history?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
Foamy podocytes and myelinosomes in a case of Fabry's disease. This patient had positive genetic testing.
#nephsky #pathsky #kidneypath #renal
#nephsky #pathsky #kidneypath #renal
October 31, 2025 at 1:02 PM
Foamy podocytes and myelinosomes in a case of Fabry's disease. This patient had positive genetic testing.
#nephsky #pathsky #kidneypath #renal
#nephsky #pathsky #kidneypath #renal