Arang Rhie
@arhie.bsky.social
Reposted by Arang Rhie
We find that 12 of the 13 WASHC1 paralogues are likely to be pseudogenes, and that the only functional WASHC1 gene is on chromosome 20, not on chromosome 9 as was previously thought.
This goes some way to explaining why so little is known about this vital gene, an integral part of the WASH complex.
This goes some way to explaining why so little is known about this vital gene, an integral part of the WASH complex.
March 12, 2024 at 2:13 PM
We find that 12 of the 13 WASHC1 paralogues are likely to be pseudogenes, and that the only functional WASHC1 gene is on chromosome 20, not on chromosome 9 as was previously thought.
This goes some way to explaining why so little is known about this vital gene, an integral part of the WASH complex.
This goes some way to explaining why so little is known about this vital gene, an integral part of the WASH complex.
Reposted by Arang Rhie
Congrats!! 👏👏 👏 This is an important piece demonstrating paralogous genes newly found in T2T-CHM13 better represents the coding form while the version in hg38 that was conceived as protein coding turned out to be a pseudogene. Also supported by the #HPRC assemblies. #T2Tgenomes
March 12, 2024 at 2:23 PM
Congrats!! 👏👏 👏 This is an important piece demonstrating paralogous genes newly found in T2T-CHM13 better represents the coding form while the version in hg38 that was conceived as protein coding turned out to be a pseudogene. Also supported by the #HPRC assemblies. #T2Tgenomes
Congrats!! 👏👏 👏 This is an important piece demonstrating paralogous genes newly found in T2T-CHM13 better represents the coding form while the version in hg38 that was conceived as protein coding turned out to be a pseudogene. Also supported by the #HPRC assemblies. #T2Tgenomes
March 12, 2024 at 2:23 PM
Congrats!! 👏👏 👏 This is an important piece demonstrating paralogous genes newly found in T2T-CHM13 better represents the coding form while the version in hg38 that was conceived as protein coding turned out to be a pseudogene. Also supported by the #HPRC assemblies. #T2Tgenomes
Reposted by Arang Rhie
Last week we also released updated T2T assemblies for the autosomes as well! Species include: chimp, bonobo, gorilla, Bornean orangutan, Sumatran orangutan, and siamang gibbon. These are making their way to GenBank, but see here for a preview: github.com/marbl/Primates Lots more analyses to come!
GitHub - marbl/Primates: Complete assemblies of non-human primate genomes
Complete assemblies of non-human primate genomes. Contribute to marbl/Primates development by creating an account on GitHub.
github.com
December 2, 2023 at 6:31 PM
Last week we also released updated T2T assemblies for the autosomes as well! Species include: chimp, bonobo, gorilla, Bornean orangutan, Sumatran orangutan, and siamang gibbon. These are making their way to GenBank, but see here for a preview: github.com/marbl/Primates Lots more analyses to come!