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arcadiascience.com
Arcadia Science
@arcadiascience.com
Research and development company leveraging the biology of diverse organisms. Read about our science: http://research.arcadiascience.com
All hardware designs, software, and documentation are open-source and available on GitHub. We'd love your feedback on what features would make AutoOpenRaman more useful for your research! [8/8]

research.arcadiascience.com/pub/resource...
AutoOpenRaman: Low-cost, automated Raman spectroscopy
We developed AutoOpenRaman, an automated, inexpensive microscope for Raman spectroscopy. We recapitulated many features of expensive commercial Raman spectroscopy systems using economical hardware and...
research.arcadiascience.com
September 16, 2025 at 6:13 PM
This resource is perfect for scientists who want to try Raman spectroscopy without committing to expensive commercial systems, or current OpenRAMAN users who want to add automation to their experiments. [7/8]
September 16, 2025 at 6:13 PM
We demonstrated AutoOpenRaman's capabilities by automatically collecting 200 Raman spectra from Chlamydomonas reinhardtii colonies in 68 minutes across a 96-well plate format. The system successfully detected β-carotene signatures in the algae. [6/8]
September 16, 2025 at 6:13 PM
The software is designed for non-programmers to install and use, built on µManager (micro-manager.org) for broad device support. Users can swap hardware components as long as µManager supports them — no code changes needed [5/8]
September 16, 2025 at 6:13 PM
On the hardware side, we added a motorized XY stage, microscope objective, laser shutter, and neon light source for quick calibration. [4/8]
September 16, 2025 at 6:13 PM
Our solution: AutoOpenRaman adds automation to OpenRAMAN while keeping it open-source and relatively inexpensive (~$8k in total). [3/8]
September 16, 2025 at 6:13 PM
The problem: Commercial Raman systems offer automation, but cost $200k+. #OpenRAMAN (open-raman.org) is a powerful, inexpensive DIY alternative, but it doesn't support automation. [2/8]
OpenRAMAN
open-raman.org
September 16, 2025 at 6:13 PM