apparaillylab.bsky.social
@apparaillylab.bsky.social
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Huge congrats to the newest doctor in our team, Olivier Bortolotti, who successfully defended his thesis @umontpellier.bsky.social after 3 years of brillant research into how #Ageing affects mouse #SynovialTissue. Proud day for the team and his supervisor Gabriel Courties 👏 to the great jury too 😉
New paper out !
"Spatial mapping of rheumatoid arthritis synovial niches reveals a LYVE1+ macrophage network associated with response to therapy" as part of the ANR SyMAC project that I coordinated in collaboration with teams @rmes-lab.bsky.social @apparaillylab.bsky.social @qmul.bsky.social 🙌
Spatial mapping of rheumatoid arthritis synovial niches reveals a LYVE1+ macrophage network associated with response to therapy - PubMed
This study provides an unprecedented spatial and dynamic blueprint of the RA synovium's response to therapy. We identify the LYVE1<sup>+</sup> macrophage network as a pivotal component of synovial hom...
pubmed.ncbi.nlm.nih.gov
August 26, 2025 at 8:46 AM
Happy to share our new study identifying a macrophage subset as a key driver of synovitis in osteoarthritis via the OSM-OSMR axis published @acr-journals.bsky.social. Congrats @GabrielCourties and #PhD students Olivier Bortolotti, Damien Laouteouet acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
Monocyte‐derived macrophages‐synovial fibroblasts crosstalk unravels oncostatin signaling network as a driver of synovitis in osteoarthritis
Objective Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origi...
acrjournals.onlinelibrary.wiley.com
July 8, 2025 at 8:03 PM
Huge congrats to the newest doctor in our team, Olivier Bortolotti, who successfully defended his thesis @umontpellier.bsky.social after 3 years of brillant research into how #Ageing affects mouse #SynovialTissue. Proud day for the team and his supervisor Gabriel Courties 👏 to the great jury too 😉
July 7, 2025 at 9:15 PM
Delighted to host at IRMB-Montpellier Meryem Aloulou, a tenured researcher @inserm.fr at INFINITY-Toulouse Institute.
She delivered an insightful seminar on "When Tregs Meet B Cells: A Dialog Shaping Immunity" in various contexts. Great presentation showcasing leading-edge #Immunology research.
July 2, 2025 at 7:27 PM
Exciting News from #INSERM U1183 at #IRMB, Montpellier! We are thrilled to announce that Mehdi Benamar has been ranked 1st by the #INSERM CSS5 jury in the highly competitive CRCN ! 🏆 Congrats to Mehdi for this decisive step towards earning a permanent research position at INSERM 👏
April 27, 2025 at 5:16 AM
Happy to attend #oarsi2025 at Incheon, Korea for the 1st time with part of my team. Great opportunity for our 3rd year PhD student, Olivier Bortolotti, to present his work on scRNAseq of aged mouse synovial joint and unexpected macrophage loss driving fibrosis.
April 26, 2025 at 6:04 AM
Célébration @Institut for Regenerative Medecine & Biothérapies (IRMB) de la journée du #8Mars avec l'opération #Coquelicots, une initiative de Association #Femmes&Sciences en partenariat avec l'association #Femmes&Mathématiques. Soyons toutes visibles et unies pour promouvoir #Égalité et #inclusion
March 8, 2025 at 9:30 AM