Angela Oill
@angela-oill.bsky.social
Computational Scientist at the Translational Genomics Research Institute
Reposted by Angela Oill
Pastoralism remains central to survival in the Turkana of northwest Kenya, where heat and water scarcity pose constant challenges. New research uncovers the genetic signatures that underlie adaptation to arid living in this pastoralist community.
Learn more this week: https://scim.ag/4nxcJbx
Learn more this week: https://scim.ag/4nxcJbx
September 18, 2025 at 6:05 PM
Pastoralism remains central to survival in the Turkana of northwest Kenya, where heat and water scarcity pose constant challenges. New research uncovers the genetic signatures that underlie adaptation to arid living in this pastoralist community.
Learn more this week: https://scim.ag/4nxcJbx
Learn more this week: https://scim.ag/4nxcJbx
Reposted by Angela Oill
So excited to share @saahimall.bsky.social just had her her first 1st author publication published in AJP lung! Huge accomplishment!!! This study wouldn't have been possible without the amazing @jensucre.bsky.social!
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity | American Journal of Physiology-Lung Cellular and Molecular Physiology | American Physiological So...
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
journals.physiology.org
August 4, 2025 at 10:25 PM
So excited to share @saahimall.bsky.social just had her her first 1st author publication published in AJP lung! Huge accomplishment!!! This study wouldn't have been possible without the amazing @jensucre.bsky.social!
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Reposted by Angela Oill
I am so excited to share our most recent work & my first big project as a graduate student! We leveraged spatial transcriptomics to study the cell-cell communication involved in human lung development. Here’s the full study: www.biorxiv.org/content/10.1...
(1/17)
(1/17)
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
www.biorxiv.org
June 6, 2025 at 6:34 PM
I am so excited to share our most recent work & my first big project as a graduate student! We leveraged spatial transcriptomics to study the cell-cell communication involved in human lung development. Here’s the full study: www.biorxiv.org/content/10.1...
(1/17)
(1/17)
Reposted by Angela Oill
Congrats to @saahimall.bsky.social on her first study from her PhD! Also, science is always more fun when done with friends. Great to work as always with @jensucre.bsky.social and @jkropski.bsky.social!
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity https://www.biorxiv.org/content/10.1101/2025.06.02.656433v1
June 5, 2025 at 5:37 PM
Congrats to @saahimall.bsky.social on her first study from her PhD! Also, science is always more fun when done with friends. Great to work as always with @jensucre.bsky.social and @jkropski.bsky.social!
Reposted by Angela Oill
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth.
Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
Best practices for improving alignment and variant calling on human sex chromosomes
Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...
www.biorxiv.org
May 7, 2025 at 1:28 PM
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth.
Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
Reposted by Angela Oill
Best practices for improving alignment and variant calling on human sex chromosomes https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
May 1, 2025 at 4:32 AM
Best practices for improving alignment and variant calling on human sex chromosomes https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
Reposted by Angela Oill
Ever wondered if there was a way to know if an individual would accept or reject a transplant organ? In this preprint, @nebanovich.bsky.social used spatial transcriptomics to study heart transplant rejection. Check out the story from GenomeWeb & the preprint! www.genomeweb.com/gene-express...
Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics https://www.biorxiv.org/content/10.1101/2025.02.28.640852v1
March 14, 2025 at 12:15 AM
Ever wondered if there was a way to know if an individual would accept or reject a transplant organ? In this preprint, @nebanovich.bsky.social used spatial transcriptomics to study heart transplant rejection. Check out the story from GenomeWeb & the preprint! www.genomeweb.com/gene-express...
I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics
Allograft rejection following solid-organ transplantation is a major cause of graft dysfunction and mortality. Current approaches to diagnosis rely on histology, which exhibits wide diagnostic variabi...
www.biorxiv.org
March 7, 2025 at 4:34 PM
I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...