Andreas Santamaria
andreassantamaria.bsky.social
Andreas Santamaria
@andreassantamaria.bsky.social
PhD in Chemistry. Expert in interfacial techniques, such as neutron reflectometry, and in protein-membrane interaction studies. Currently working with AFM and fluorescence techniques on protein droplets at the Centre de Biologie Structurale in Montpellier.
At the @cbsmontpellier.bsky.social we equipped the JKP atomic force microscope, mounted on an inverted microscope, with photothermal excitation. This custom-built optical pathway focuses a laser onto the cantilever in our correlative AFM–fluorescence microscopy setup. @costaluca.bsky.social
November 7, 2025 at 4:30 PM
I am pleased that this paper has finally been published!

It includes data from my PhD thesis, showing how to evaluate protein orientation upon membrane binding by employing neutron reflectometry.

It's a great work that made use of several biophysical techniques.

www.nature.com/articles/s42...
Structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes - Communications Chemistry
To selectively internalize proteins into the endosomal system, eukaryotic cells rely on clathrin adaptors such as the clathrin assembly lymphoid myeloid leukaemia protein (CALM), but details regarding...
www.nature.com
July 31, 2025 at 8:37 AM
It has been extremely fun and interesting to take part in the 7th Workshop and School on Frontiers in Water Biophysics, in Erice (Sicily).

It was a pleasure to exchange ideas with other scientists, and it was an honour to receive the "Best Young Researcher Award".

#research #postdoc #condensates
July 8, 2025 at 12:12 PM
I am happy and excited to find out that the AFM-based methodology I developed during my post-doc has been included in this trend: "AFM multiparametric characterization of LLPS in plants"

#research #postdoc #condensates #LLPS #AFM #fluorescence

www.cell.com/trends/plant...
AFM multiparametric characterization of LLPS in plants
Liquid–liquid phase separation (LLPS) plays a crucial role in cellular processes. Atomic force microscopy (AFM) is notable for multiparametric imaging of LLPS condensates, enabling investigation of th...
www.cell.com
January 17, 2025 at 1:56 PM