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AndiArisen !Commissions open!

@andiarisen.bsky.social

390 followers 960 following 190 posts

🔞| 28 | She/They | 🔞

The baa player of deadlock

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AndiArisen !Commissions open! @andiarisen.bsky.social · Nov 27

Commissions are still open! $80 for arts with full background and shading +$30 for each additional character. $35 for a shaded bust and $20 for a profile pic. 2 slots available Payments are done via hipolink (paypal)

Vera Oberlin low angle show on a balcony with a sun-protecting webbing

A goo dragon with skeleton head and a ghost hydra dragon eating buns at a cafe labeled dragon cafe, with some interior visible (menu and some plant decorations behind the glass)

A fursona of St. Bernard wearing glasses pictured in teal-red lighting

Jade Harley manipulating the 4 planets of homestuck beta kids with space and stars as background

Reposted by AndiArisen !Commissions open!

✨Toot✨

@tootsnoot.bsky.social

what if Ivy hit you with this look?

November 19, 2025 at 7:45 PM

Reposted by AndiArisen !Commissions open!

Culture Crave 🍿

@culturecrave.co

#Dispatch devs have no interest in using AI for game development 🎮

"AI feels like a production solution, not a creative one. Maybe it's a creative one if you aren't creative"

"Whatever we're building, it has to connect. It's got to be made by people. It's got to connect to people"

(via GIBiz)

November 18, 2025 at 12:37 AM

Reposted by AndiArisen !Commissions open!

Rashuu | Revenant plushie on 📌

@rashuu.bsky.social

Undertaker🩸
#Nightreign #Eldenring

November 18, 2025 at 11:19 AM

Reposted by AndiArisen !Commissions open!

Lughost

@lughostin.bsky.social

Stocking !

November 18, 2025 at 11:40 AM

Reposted by AndiArisen !Commissions open!

Wavy

@wavy667.bsky.social

Doodle from Sunday that I forgor to post here
| #Deadlock | #DeadlockFanart | #Art |

A quick doodle of Mina Ha from Deadlock. She is drawn from the bust up, leaning slightly backwards with he hand up near her mouth

November 18, 2025 at 11:54 AM

Reposted by AndiArisen !Commissions open!

Luloid

@etoluloid.bsky.social

Arin's Poise
Pocket deadlock

November 14, 2025 at 7:51 AM

Reposted by AndiArisen !Commissions open!

울새ulsae

@ulsae.bsky.social

Victor wearing Frank's pants

Deadlock
Victor

November 17, 2025 at 4:06 PM

Reposted by AndiArisen !Commissions open!

Penny Parker

@snapcube.gay

i get why this is common consensus but ppl being like "the steam controller is kinda ugly but the functionality is great!" makes me shake my head. i think it looks beautiful. shes so unique and tall. the thumbsticks look shiny gorgeous. the slight rotation on the trackpads is so playful.

November 17, 2025 at 12:36 AM

Reposted by AndiArisen !Commissions open!

Chise

@sailorrooscout.bsky.social

Chemists discovered a powerful hidden antibiotic that’s 100 times stronger than existing ones and effective against deadly superbugs.

The study has been published in the Journal of the American Chemical Society. YES, it is PEER-REVIEWED.
• pubs.acs.org/doi/10.1021/...

🧪🧵⬇️

Summary
A team of scientists discovered a hidden antibiotic 100 times stronger than existing drugs against deadly superbugs like MRSA. The molecule had been overlooked for decades in a familiar bacterium. It shows no signs of resistance so far, offering hope in the fight against drug-resistant infections and paving the way for new approaches to antibiotic discovery.

Abstract
The methylenomycins are highly functionalized cyclopentanone antibiotics produced by Streptomyces coelicolor A3(2). A biosynthetic pathway to the methylenomycins has been proposed based on sequence analysis of the proteins encoded by the methylenomycin biosynthetic gene cluster and the incorporation of labeled precursors. However, the roles played by putative biosynthetic enzymes remain experimentally uninvestigated.
Here, the biosynthetic functions of enzymes encoded by mmyD, mmyO, mmyF, and mmyE were investigated by creating in-frame deletions in each gene and investigating the effect on methylenomycin production.
No methylenomycin-related metabolites were produced by the mmyD mutant, consistent with the proposed role of MmyD in an early biosynthetic step. The production of methylenomycin A, but not methylenomycin C, was abolished in the mmyF and mmy mutants, consistent with the corresponding enzymes catalyzing the epoxidation of methylenomycin C, as previously proposed. Expression of mmyF and mmyo in a S. coelicolor M145 derivative engineered to express mmr, which confers methylenomycin resistance, enabled the resulting strain to convert methylenomycin C to methylenomycin A, confirming this hypothesis.
A novel metabolite (premethylenomycin C), which readily cyclizes to form the corresponding butanolide (premethylenomycin C lactone), accumulated in the mmyE mutant, indicating the corresponding enzyme is involved in introducing the exomethylene group into methylenomycin C.

Remarkably, both premethylenomycin C and its lactone precursor were one to two orders of magnitude more active against various Gram-positive bacteria, including antibiotic-resistant Staphylococcus aureus and Enterococcus faecium isolates, than methylenomycins A and C, providing a promising starting point for the development of novel antibiotics to combat antimicrobial resistance.

November 16, 2025 at 7:32 PM

Reposted by AndiArisen !Commissions open!

Squawq

@squawq7.bsky.social

November 13, 2025 at 8:43 PM

Reposted by AndiArisen !Commissions open!

Ada Phoebe

@reikachang.bsky.social

"The only way this day gets any better is if I get to punch Lash in the face!"

After several iterations and 1 and a half months of working on him, my Bebop redesign is finally completed, sporting a V8, a hook, and a stolen Fairfax laser

#conceptart #deadlock #deadlockfanart