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Acta Materia Medica
@amm-journal.org
37 followers 35 following 40 posts
Advancing global pharmaceutical research.
Platinum Open Access • CiteScore 8.1 • No author processing charges.
https://amm-journal.org/
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Acta Materia Medica @amm-journal.org · Jun 19
We’re proud to announce that @amm-journal.org has achieved an impressive #CiteScore of 8.1!

This places us 1st out of 33 journals in the field of #OccupationalTherapy.

A heartfelt thank you to our editorial team, authors, reviewers, and supportive readers.

#OpenAccess: amm-journal.org
amm-journal.org
This study presents a response regression model for analyzing #Transcriptomic data on #ViralInfection, which serves as a guiding principle to identify specific target host factors influenced by the #Pharmacological effects of host-targeted #Antivirals.

#OpenAccess: amm-journal.org/index.php/20...
Response regression model as a guiding principle for pharmacological mechanistic investigation of host-targeted antivirals
Using a response regression model as a guiding principle to precisely explore the pharmacological mechanisms of host-targeted antiviral (HTA) agents.
amm-journal.org
November 20, 2025 at 2:11 PM
amm-journal.org
This study identifies Vina-ginsenoside R18, a #triterpenoid #saponin from #PanaxNotoginseng, as the first dual inhibitor of DENV E protein and RdRp, blocking #ViralEntry and replication, and effectively suppressing #dengue infection in vitro & in vivo.

#OpenAccess: amm-journal.org/index.php/20...
Discovery of vina-ginsenoside R18 as a novel dual-target inhibitor of dengue virus envelope protein and RNA-dependent RNA polymerase
Vina-ginsenoside R18, acts as the first dual inhibitor of dengue virus E protein and RdRp, blocking viral entry and replication effectively
amm-journal.org
November 3, 2025 at 12:42 PM
amm-journal.org
A comprehensive overview of the sources, structural diversity, #bioactivities, and biosynthetic pathways of benzo-fused ten-membered ring #meroterpenoids reported between 1980 and 2024 highlighting their potential in next-generation drug development.

#OpenAccess: amm-journal.org/index.php/20...
Benzo-fused ten-membered ring meroterpenoids: sources, chemical diversity, biological activities, and biosynthesis
Reviewing the sources, structural diversity, bioactivities, and biosynthetic pathways of benzo-fused ten-membered ring meroterpenoids.
amm-journal.org
November 3, 2025 at 12:11 PM
amm-journal.org
This review provides a detailed overview of the #antimicrobial, antiparasitic, antiviral, and #anticancer effects of various bioactive guanidine alkaloids isolated from different marine species.

#OpenAccess: amm-journal.org/index.php/20...
Biologically Active Guanidine Alkaloids
An overview of antimicrobial, antiparasitic, antiviral, and anticancer properties of bioactive guanidine alkaloids.
amm-journal.org
August 13, 2025 at 12:14 PM
amm-journal.org
This review provides an overview of the latest progress and challenges in #bioresponsive materials, and details the applications of different #biomaterials and their effective #DrugDelivery mechanisms in #DiabetesMellitus.

#OpenAccess: amm-journal.org/index.php/20...
Innovations and challenges in bioresponsive materials for effective drug delivery in diabetes mellitus
Reviewing the latest progress and challenges in bioresponsive materials and their application for effective drug delivery in diabetes mellitus.
amm-journal.org
July 10, 2025 at 10:02 AM
amm-journal.org
In this study, scientists discovered that #rutin, an active ingredient from the extract of #caryotamaxima leaves, possesses #geroprotective effects mediated by #LipidMetabolism regulation via DAF-2 downstream signaling pathways.

#OpenAccess: amm-journal.org/index.php/20...
Caryota maxima leaf extract extends Caenorhabditis elegans lifespan by inducing mono-unsaturated fatty acid accumulation via DAF-2 signaling
Identification of a novel herbal extract and its active ingredient as a natural geroprotector with anti-aging effects
amm-journal.org
July 4, 2025 at 11:15 AM
amm-journal.org
An overview on the structure, activation & downstream effects of #gasdermin with implications in various diseases and #targeteddrugdevelopment. #Pyroptosis, #DAMPs #GSDMoligomerization #GSDMDagonists #DrugDelivery

#OpenAccess: amm-journal.org/index.php/20...
Advances in gasdermin activation, regulation, and targeted drug development - AMM Journal
Comprehesive outlook on Gasdermin
amm-journal.org
July 3, 2025 at 10:32 AM
amm-journal.org
This article reviews the advancements and challenges in #transdermal #insulin delivery systems, with a special focus on #microneedle transdermal delivery, and discusses current limitations and future prospects.

#OpenAccess:
www.scienceopen.com/hosted-docum...
Formulation approaches and strategies for transdermal delivery of insulin: special emphasis on microneedle-based systems
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1280308e163">The prevalence of diabetes is increasing and expected to become a major global health bu...
www.scienceopen.com
July 1, 2025 at 10:56 AM
amm-journal.org
We’re proud to announce that @amm-journal.org has achieved an impressive #CiteScore of 8.1!

This places us 1st out of 33 journals in the field of #OccupationalTherapy.

A heartfelt thank you to our editorial team, authors, reviewers, and supportive readers.

#OpenAccess: amm-journal.org
June 19, 2025 at 6:47 AM
amm-journal.org
This review summarizes the recent findings of #SREBPs mainly in terms of physiologic activation processes, regulatory processes, related diseases, and publicly available #SmallMoleculeInhibitors with #therapeuticpotential.

#OpenAccess: amm-journal.org/index.php/20...

#medsky #medicalresearch
Therapeutic strategies targeting SREBP transcription factors
Mechanism of action underlying SREBP in different diseases and its targeted inhibition for disease prevention and treatment.
amm-journal.org
June 16, 2025 at 10:00 AM
amm-journal.org
Catalpol a natural neuroprotective agent may help treat neurologic disorders by reducing inflammation and stress.

amm-journal.org/index.php/20...

#CatalpolResearch #RehmanniaeRadixBenefits #NeurologicHealth #NeuroprotectionMechanisms #BrainSignalingPathways #NeurologicalDisorders
Catapol: a promising natural neuroprotective agent for neurologic disorders
Neuroprotective mechanism of catalpol against various neurological disorders
amm-journal.org
May 29, 2025 at 8:25 AM
amm-journal.org
PROTACs are redefining drug discovery by enabling selective degradation of disease-driving proteins. From targeting the undruggable to overcoming resistance, PROTACs hold the key to next-gen precision therapies.

amm-journal.org/index.php/20...

#PROTAC #DrugDiscovery #TargetedTherapy #Biotech
PROTACs improve selectivity for targeted proteins
PROTACs offer a novel approach to degrade disease-causing proteins, showing promise in targeting cancers and drug-resistant proteins with high selectivity.
amm-journal.org
May 21, 2025 at 12:02 PM
amm-journal.org
Ferroptosis by nanomaterials: targeting cancer stem cells and overcoming drug resistance

amm-journal.org/index.php/20...

#Ferroptosis #drugresistance #cancerstemcell #nanomaterials
Ferroptosis by nanomaterials: targeting cancer stem cells and overcoming drug resistance
Ferroptosis-focused nanomaterials eradicate cancer stem cells and overcome drug resistance via iron-driven lipid peroxidation in precision oncology
amm-journal.org
May 19, 2025 at 7:32 AM
amm-journal.org
Revolutionizing HIV treatment with lenacapavir: first capsid inhibitor overcoming drug resistance, long-acting efficacy, 100% prophylaxis success.

amm-journal.org/index.php/20...

#HIV1CapsidProtein #Lenacapavir #NuclearPoreComplex #NuclearTranslocation #DrugDesign #HIVtreatment
Revolutionizing HIV treatment: unveiling the new frontiers of HIV capsid research
Revolutionizing HIV treatment with lenacapavir: first capsid inhibitor overcoming drug resistance, long-acting efficacy, 100% prophylaxis success.
amm-journal.org
May 15, 2025 at 1:00 PM
amm-journal.org
Discover Wedelolactone (WDL), a natural PDE4 inhibitor from Eclipta prostrata. Safe, effective topical psoriasis therapy with clinical potential.

amm-journal.org/index.php/20...

#Ecliptaprostrata #Wedelolactone #Phosphodiesterase4inhibitor #Psoriasis #Moleculardynamicssimulation
Discovery of wedelolactone from Eclipta Prostrata (L.) Linn. as a natural PDE4 inhibitor with potent anti-psoriasis effects
Discover Wedelolactone (WDL), a natural PDE4 inhibitor from Eclipta prostrata. Safe, effective topical psoriasis therapy with clinical potential.
amm-journal.org
May 15, 2025 at 12:58 PM
amm-journal.org
LW, a #MoracinM derivative, inhibits #PDE4, reduces inflammation, and improves psoriasis symptoms, showing strong therapeutic potential with fewer side effects.

Read More: tinyurl.com/3pvwextj

#PDE4inhibitor #psoriasis #inflammatoryfactor #AMMJournal @scienceopen.bsky.social
Moracin M derivative targeting PDE4 for the treatment of psoriasis
LW, a Moracin M derivative, inhibits Phosphodiesterase-4 (PDE4), reduces inflammation, and improves psoriasis symptoms, showing strong therapeutic potential with fewer side effects.
tinyurl.com
March 28, 2025 at 11:24 AM
amm-journal.org
Berberine (BBR) inhibits phagocytosis and inflammation via the TLR4-PI3K-CDC42 pathway, suppressing NF-κB signaling and key inflammatory markers in #macrophages.

Read More: tinyurl.com/4ktmt2pd

#Berberine #Phagocytosis #TLR4-PI3K-CDC42 #AMMJournal @scienceopen.bsky.social
Berberine inhibits phagocytosis through the TLR4-PI3K-CDC42 pathway
Berberine inhibits phagocytosis and inflammation via the TLR4-PI3K-CDC42 pathway, suppressing NF-κB signaling and key inflammatory markers in macrophages.
tinyurl.com
March 25, 2025 at 10:35 AM
amm-journal.org
A nanoplatform with photosensitizers and metal ions enables tumor imaging and multimodal therapy, achieving complete tumor elimination in preclinical studies.

Read More: amm-journal.org/index.php/20...

#Supramolecularphotosensitizer #cancertherapy @scienceopen.bsky.social
Natural supramolecular photosensitizer with in situ switchable photothermal/photodynamic effects as an imaging platform for precise and controlled cancer synergistic therapy
A nanoplatform with Supramolecular photosensitizer and metal ions enables tumor imaging and multimodal therapy, achieving complete tumor elimination in preclinical studies.
amm-journal.org
March 12, 2025 at 11:48 AM
amm-journal.org
We would like to thank the reviewers who contributed to Acta Materia Medica Volume 3 (2024). Your efforts play a vital role in maintaining the quality of our journal. See the full list of reviewers here: amm-journal.org/index.php/ac...

#ThankYouReviewers #PeerReview #AcademicPublishing
March 12, 2025 at 9:54 AM
amm-journal.org
Explore coumarin derivatives as potential drugs! Learn about their inhibitory mechanisms against monoamine oxidase. #DrugDiscovery #MAOInhibitors

Read More: amm-journal.org/index.php/20...

#Enzymeinhibition #Drugdiscovery #Neuropharmacology #Medicinalchemistry @scienceopen.bsky.social
Coumarin derivatives as inhibitors against monoamine oxidase: structure-activity relationships and inhibitory mechanisms
Explore the structure-activity relationships and inhibitory mechanisms of coumarin derivatives as inhibitors against monoamine oxidase (MAO). Learn about their potential applications in neuropharmacol...
amm-journal.org
March 10, 2025 at 1:55 PM
amm-journal.org
Randomized, waitlist-controlled trial of #Cordycepssinensis mycelium culture extract (#Cs4) for #longCOVID patients in Hong Kong.

Read More: amm-journal.org/index.php/20...

#randomizedtrial #modifiedCOVID19 #YorkshireRehabilitationScale #C19YRSm @scienceopen.bsky.social
Randomized, waitlist-controlled trial of Cordyceps sinensis mycelium culture extract (Cs4) for long COVID patients in Hong Kong
Cordyceps sinensis mycelium culture extract (Cs4) were assessed for alleviating long COVID symptoms. In this randomized trial 110 participants were assigned to receive Cs4 (55 participants) or were wa...
amm-journal.org
March 10, 2025 at 11:48 AM
amm-journal.org
New study alert! EGCG mitigates acetaminophen-induced liver injury by stabilizing HUWE1 and suppressing ferroptosis. Discover innovative DILI therapies: amm-journal.org/index.php/20...

#LiverResearch #EGCG #DILI #Ferroptosis #BiomedicalResearch
EGCG inhibits ferroptosis to ameliorate APAP-induced liver injury by suppressing NEDD8 and stabilizing HUWE1 in vivo and in vitro - AMM Journal
EGCG stabilizes HUWE1 and degrades TFR1 to suppress ferroptosis, mitigating APAP-induced liver injury. Discover novel DILI treatment insights for researchers.
amm-journal.org
February 25, 2025 at 10:14 AM
amm-journal.org
New review: How does cholestasis trigger depression? Discover how bile acids disrupt the BBB, drive neuroinflammation, and affect the gut-brain axis. Learn more: amm-journal.org/index.php/20...

#Cholestasis #DepressionResearch #Neuroendocrine #GutBrainAxis #LiverDisease
Pathologic and therapeutic insights into cholestatic liver disease-associated depressive disorder
Uncover neuroendocrine links in cholestasis-induced depression: bile acid accumulation disrupts the BBB and gut-brain axis, revealing new therapeutic targets.
amm-journal.org
February 25, 2025 at 10:12 AM
amm-journal.org
Exploring food and medicine homology for innovative cancer treatments! FMH bridges nutrition & pharmacology, offering low-toxicity, patient-friendly therapies. A game-changer in oncology!

Read more: amm-journal.org/index.php/20...

#cancerresearch #foodasmedicine #FMH #oncology #integrativemedicine
Exploring food and medicine homology: potential implications for cancer treatment innovations
Food and medicine homology (FMH) offers a promising approach to cancer treatment, combining nutrition and pharmacology for low-toxicity, effective therapies.
amm-journal.org
February 25, 2025 at 10:07 AM
amm-journal.org
Antineoplastic effects of #Icaritin acting through various molecular mechanisms. Its potential applications in #cancertherapy continue to expand.

Read More: tinyurl.com/2e67ex3e

#traditionalChinesemedicine #hepatocellularcarcinoma #molecularmechanism #ammjournal @scienceopen.bsky.social
Antineoplastic effects of icaritin: molecular mechanisms and applications
Antineoplastic effects of Icaritin acting through various molecular mechanisms. Its potential applications in cancer therapy continue to expand.
tinyurl.com
February 21, 2025 at 12:18 PM