Amaia Lujambio
amaialujambio.bsky.social
Amaia Lujambio
@amaialujambio.bsky.social
Associate Professor at Mount Sinai (NY). Liver cancer research.
Looking forward to seeing how the field evolves in the next few years.
November 21, 2024 at 5:42 PM
Our study demonstrates that the male predominance observed in hepatocellular carcinoma is abolished in those tumors with high levels of NOTCH1 through an immune mechanism that involves genes in sex chromosomes.
November 21, 2024 at 5:42 PM
Our study demonstrates that the male predominance observed in hepatocellular carcinoma is abolished in those tumors with high levels of NOTCH1 through an immune mechanism that involves genes in sex chromosomes.
November 21, 2024 at 5:42 PM
Our study builds on previous work from Amy Moran, Ron Depinho, Dan Theodorescu, and @gbm-maestro.bsky.social Justin Lathia for highlighting the importance of sex in immune responses in cancer.
November 21, 2024 at 5:42 PM
Many thanks to Tisch Cancer Institute, Precision Immunology Institute, Sinai Liver, Damon Runyon Cancer Research Foundation, and NIH/NCI for their constant support!
November 21, 2024 at 5:42 PM
Many thanks to all the member of the Lujambio lab and our collaborators Alice Kamphorst, Alex Tsankov (Sinai), and Yulei Wang from @genentech for making this story possible!
November 21, 2024 at 5:42 PM
I would like to thank Michele Hartsough from Cancer Discovery for guiding us in making our story more impactful and for a productive editorial experience.
November 21, 2024 at 5:42 PM
Katie will soon publish the rest of her PhD work on the role of NOTCH1 in HCC and cancer plasticity. Her unpublished work is already available in bioxriv and complements the story published in Cancer Discovery: www.biorxiv.org/content/10.1...
NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma
Liver cancer, the third leading cause of cancer-related mortality worldwide, has two main subtypes: hepatocellular carcinoma (HCC), accounting most of the cases, and cholangiocarcinoma (CAA). NOTCH pa...
www.biorxiv.org
November 21, 2024 at 5:42 PM
Can you add me please? Thanks!
November 14, 2024 at 8:15 PM