Alister Burt
@alisterburt.bsky.social
Computational Cryo-EM/ET at Genentech
Love people, the outdoors and building stuff
Complexity is the enemy
All opinions my own
Love people, the outdoors and building stuff
Complexity is the enemy
All opinions my own
😂😂😂 don’t give them ideas
November 11, 2025 at 5:08 AM
😂😂😂 don’t give them ideas
great tip, thanks!
November 1, 2025 at 6:54 PM
great tip, thanks!
“are we still living off the dividends from ideas that were nurtured, and risks that were taken, a half century ago”
November 1, 2025 at 5:28 PM
“are we still living off the dividends from ideas that were nurtured, and risks that were taken, a half century ago”
the bot!! Thank you 🙏
November 1, 2025 at 5:27 PM
the bot!! Thank you 🙏
positive note: you might be interested in trying out pixi for managing environments - made by the mamba team, per-project UX is nice and global installs are nice
e.g ‘pixi global install warp -c warpem -c nvidia/label/cuda-11.8.0 -c pytorch’ for an installation of WarpTools with no envs
e.g ‘pixi global install warp -c warpem -c nvidia/label/cuda-11.8.0 -c pytorch’ for an installation of WarpTools with no envs
November 1, 2025 at 4:37 PM
positive note: you might be interested in trying out pixi for managing environments - made by the mamba team, per-project UX is nice and global installs are nice
e.g ‘pixi global install warp -c warpem -c nvidia/label/cuda-11.8.0 -c pytorch’ for an installation of WarpTools with no envs
e.g ‘pixi global install warp -c warpem -c nvidia/label/cuda-11.8.0 -c pytorch’ for an installation of WarpTools with no envs
makes sense! Anaconda Inc speedrunning ‘how to kill adoption of your own open source infrastructure through aggressive monetization’ has poisoned the well and damaged the ecosystem as a whole, it’s sad to see
www.goodreads.com/book/show/22...
www.goodreads.com/book/show/22...
Enshittification: Why Everything Suddenly Got Worse and…
Explaining the process of the “enshittification” of dig…
www.goodreads.com
November 1, 2025 at 4:29 PM
makes sense! Anaconda Inc speedrunning ‘how to kill adoption of your own open source infrastructure through aggressive monetization’ has poisoned the well and damaged the ecosystem as a whole, it’s sad to see
www.goodreads.com/book/show/22...
www.goodreads.com/book/show/22...
where are you hitting issues?
November 1, 2025 at 2:01 PM
where are you hitting issues?
their legal battles and the overlapping names of different conda related things have unfortunately made a bunch of people more allergic to the word conda than they otherwise were 😭
November 1, 2025 at 1:33 AM
their legal battles and the overlapping names of different conda related things have unfortunately made a bunch of people more allergic to the word conda than they otherwise were 😭
there is also some nuance here: conda the package manager is free, conda-forge the community maintained repository of open source packages is free, anaconda inc and their distribution of open source conda packages vetted for legal compliance reasons is not free and recently started chasing $$$
November 1, 2025 at 1:33 AM
there is also some nuance here: conda the package manager is free, conda-forge the community maintained repository of open source packages is free, anaconda inc and their distribution of open source conda packages vetted for legal compliance reasons is not free and recently started chasing $$$
October 31, 2025 at 10:47 PM