Alexandre Hervé
alexhv.bsky.social
Alexandre Hervé
@alexhv.bsky.social
PhD student at Institut Pasteur / MDM Lab: mining ancestral immune modules across domains of life to uncover novel immune proteins in eukaryotes.
Reposted by Alexandre Hervé
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery https://www.biorxiv.org/content/10.1101/2025.04.02.646746v1
April 2, 2025 at 4:16 PM
Reposted by Alexandre Hervé
What is the diversity of antiphage systems out there ?

We used protein and genomic language models (and defense score!) to start bringing some answers: >45 000 protein families.

Leb by E. Mordret.
www.biorxiv.org/content/10.1...

Interactive UMAP to have fun
mdmparis.github.io/antiphage-la...
January 9, 2025 at 1:18 PM