Alex Hughson
alexhughson.bsky.social
Alex Hughson
@alexhughson.bsky.social
PhD Student, University of Pittsburgh
Reposted by Alex Hughson
@pitt-pmi.bsky.social PhD student Zac Ingram's @asm.org #mBio paper is out! His study shows that sequential binding of host proteins CypA and CPSF6 to HIV-1 capsid is required for optimal nuclear entry, integration, and infection. journals.asm.org/doi/10.1128/...
Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration | mBio
Human immunodeficiency virus (HIV) encodes a protein that forms a conical shell, called a capsid, that surrounds its genome. The capsid has been shown to protect the viral genome from innate immune sensors in the cell, to help transport the genome toward ...
journals.asm.org
March 2, 2025 at 4:01 PM