Akshay Vishwanatha
@akshayv.bsky.social
Cell and molecular biologist studying how human malaria parasites repair their DNA and maintain the integrity of their genome.
Pinned
Akshay Vishwanatha
@akshayv.bsky.social
· Apr 21
Plasmodium falciparum DNA repair dynamics reveal unique roles for TLS polymerases and PfRad51 in genome diversification
The haploid malaria parasite, Plasmodium falciparum, evolved a unique cohort of DNA repair pathways enabling the parasite to survive in a vertebrate host red blood cell and the mosquito vector. P. fal...
www.biorxiv.org
Wondered how malaria parasites are able to evade human immune system by increasing the number of virulence genes? Read our preprint! We show how deficiencies in DNA repair mechanisms specific to core genome and subtelomeric regions enable parasites to achieve this.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Wondered how malaria parasites are able to evade human immune system by increasing the number of virulence genes? Read our preprint! We show how deficiencies in DNA repair mechanisms specific to core genome and subtelomeric regions enable parasites to achieve this.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Plasmodium falciparum DNA repair dynamics reveal unique roles for TLS polymerases and PfRad51 in genome diversification
The haploid malaria parasite, Plasmodium falciparum, evolved a unique cohort of DNA repair pathways enabling the parasite to survive in a vertebrate host red blood cell and the mosquito vector. P. fal...
www.biorxiv.org
April 21, 2025 at 8:12 PM
Wondered how malaria parasites are able to evade human immune system by increasing the number of virulence genes? Read our preprint! We show how deficiencies in DNA repair mechanisms specific to core genome and subtelomeric regions enable parasites to achieve this.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...