Aileen Cohen
aileencohen.bsky.social
Aileen Cohen
@aileencohen.bsky.social
PhD student | Barkai lab 🧬| The Weizmann Institute of Science

Interested in transcriptional cofactors, DNA-binding proteins, and gene regulation
Reposted by Aileen Cohen
Hot from the press!🔥
Excited to share our recent Perspective on the role of intrinsically disordered regions of eukaryotic transcription factors in the target search process 🔎:
www.nature.com/articles/s41... 😱
Intrinsically disordered regions as facilitators of the transcription factor target search - Nature Reviews Genetics
Intrinsically disordered domains (IDRs) are increasingly appreciated as important components of protein function. This Perspective discusses the emerging evidence for IDRs from transcription factors a...
www.nature.com
February 21, 2025 at 1:21 PM
Maybe a bit late, but I want to bring this article to this platform as well!

Incredible work done by Vladimir Mindel and Dr. Sagie Brodsky!

academic.oup.com/nar/article/...
Revisiting the model for coactivator recruitment: Med15 can select its target sites independent of promoter-bound transcription factors
Abstract. Activation domains (ADs) within transcription factors (TFs) induce gene expression by recruiting coactivators such as the Mediator complex. Coact
academic.oup.com
November 21, 2024 at 8:43 AM