Allison Chang
@aebchang.bsky.social
MD, PhD. Neuroscientist ➡️ Thoracic Onc Fellow at MGB/DFCI. Cat mom. Human mom. Wife. Opinions mine.
Dr. Florian Fintelmann laid out a clear and compelling case for clinician involvement in #AI #ML model training, validation, and implementation.
AI is coming to healthcare whether we like it or not, and it is up to us to help sculpt it to best serve our patients. #lcsm #ASCO2025
AI is coming to healthcare whether we like it or not, and it is up to us to help sculpt it to best serve our patients. #lcsm #ASCO2025
June 2, 2025 at 5:25 PM
Powerful talk by #lungcancerscreening visionary Dr. Nasser Hanna, with a call to action and a blueprint for improving #lungcancer survival through early detection in your community. 🚨 💪 #lcsm
June 2, 2025 at 5:13 PM
Powerful talk by #lungcancerscreening visionary Dr. Nasser Hanna, with a call to action and a blueprint for improving #lungcancer survival through early detection in your community. 🚨 💪 #lcsm
Thank you @ascocancer.bsky.social @conquercancer.bsky.social #FCancer for funding our study quantifying cancer risk in those w/ #lungcancer family hx using #ML #AI
🙏 This project wouldn’t have been possible w/o the mentorship of @leciasequist.bsky.social + guidance of @jillfeldman4.bsky.social.
🙏 This project wouldn’t have been possible w/o the mentorship of @leciasequist.bsky.social + guidance of @jillfeldman4.bsky.social.
June 1, 2025 at 3:14 PM
Thank you @ascocancer.bsky.social @conquercancer.bsky.social #FCancer for funding our study quantifying cancer risk in those w/ #lungcancer family hx using #ML #AI
🙏 This project wouldn’t have been possible w/o the mentorship of @leciasequist.bsky.social + guidance of @jillfeldman4.bsky.social.
🙏 This project wouldn’t have been possible w/o the mentorship of @leciasequist.bsky.social + guidance of @jillfeldman4.bsky.social.
Reposted by Allison Chang
Don’t miss research at #ASCO25: This study presented by @danafarber.bsky.social later today looks at colon cancer and diet, suggesting diet may influence cancer outcomes after diagnosis and treatment.
Press release here: bit.ly/3FobT0z
Press release here: bit.ly/3FobT0z
June 1, 2025 at 12:00 PM
Don’t miss research at #ASCO25: This study presented by @danafarber.bsky.social later today looks at colon cancer and diet, suggesting diet may influence cancer outcomes after diagnosis and treatment.
Press release here: bit.ly/3FobT0z
Press release here: bit.ly/3FobT0z
Such an honor to speak at #EmTechCaribbean @mittechreviewbr.bsky.social about the development/deployment of #AI/#ML models in healthcare.
My tl;dr—We are now more limited by scarcity of quality data than by computational power. We must invest in building large, accurate, representative datasets.
My tl;dr—We are now more limited by scarcity of quality data than by computational power. We must invest in building large, accurate, representative datasets.
March 20, 2025 at 8:49 PM
Such an honor to speak at #EmTechCaribbean @mittechreviewbr.bsky.social about the development/deployment of #AI/#ML models in healthcare.
My tl;dr—We are now more limited by scarcity of quality data than by computational power. We must invest in building large, accurate, representative datasets.
My tl;dr—We are now more limited by scarcity of quality data than by computational power. We must invest in building large, accurate, representative datasets.
Outstanding video explaining Sybil, a powerful new AI model built by my mentor @leciasequist.bsky.social, Regina Barzilay, Florian Fintelmann et al that will change how we think about predicting future illness--starting with #lungcancer! #LCSM @massgeneralbrigham.bsky.social @scinews.bsky.social
As lung cancer rates rise in nonsmokers, a troubling trend for the #1 deadliest cancer, we hope more hospitals adopt tools like Sybil, an AI model built by #JameelClinic and @massgeneralbrigham.bsky.social researchers that predicts lung cancer risk up to 6 years in advance. youtu.be/xGSiP8i4VbU
How AI predicts lung cancer risk 6 years in advance
YouTube video by MIT Jameel Clinic - AI & Health
youtu.be
January 24, 2025 at 3:17 PM
Outstanding video explaining Sybil, a powerful new AI model built by my mentor @leciasequist.bsky.social, Regina Barzilay, Florian Fintelmann et al that will change how we think about predicting future illness--starting with #lungcancer! #LCSM @massgeneralbrigham.bsky.social @scinews.bsky.social
Reposted by Allison Chang
We have known for decade+ that you can detect progression using ctDNA months before you see it on scans. But until we show that it impacts outcomes to change tx earlier all it does is make ppl anxious and abandon treatments (TKIs) that may still be helping. Most MRD use today is marketing over data.
Why aren’t more oncologists using MRD tests like Signatera or Guardant Reveal to proactively treat NSCLC before PD shows up on imaging especially in later treatment lines? www.jto.org/article/S155...
Longitudinal Analyses of Circulating Tumor DNA for the Detection of EGFR Mutation-Positive Advanced NSCLC Progression During Treatment: Data From FLAURA and AURA3
EGFR tyrosine kinase inhibitor (EGFR-TKI)-sensitizing and -resistance mutations may be detected in plasma through circulating tumor DNA (ctDNA). Circulating tumor DNA level changes reflect alterations in tumor burden and could be a dynamic indicator of treatment effect. This analysis aimed to determine whether longitudinal EGFR-mutation ctDNA testing could detect progressive disease (PD) before radiologic detection.
www.jto.org
December 8, 2024 at 1:06 PM
We have known for decade+ that you can detect progression using ctDNA months before you see it on scans. But until we show that it impacts outcomes to change tx earlier all it does is make ppl anxious and abandon treatments (TKIs) that may still be helping. Most MRD use today is marketing over data.
