Diane Adjavon
adjavon.bsky.social
Diane Adjavon
@adjavon.bsky.social
Machine Learning Researcher 🖥🔬🧫 🦆 @ Funke Lab, #HHMIJanelia
Views my own.
Using QuAC, we can translate a GABA synapse into an ACh synapse by making minimal changes (highlighted). The images are much easier to compare: now we see that the post-synaptic density got darker.

Now that we know what to look for, we can actually see this feature in the examples above!

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January 15, 2025 at 8:27 PM
We developed QuAC specifically for biomedical applications.

Here is our favorite example: it is really difficult to notice any obvious differences between EM images of synapses releasing different neurotransmitters (e.g., GABA vs. ACh). There is just too much going on!

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January 15, 2025 at 8:24 PM
Wouldn’t it be easier if we could make paired images that only differ in class-relevant features?

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January 15, 2025 at 8:13 PM
Can you spot the difference between the cells on the left and right?

Read on for the solution (and a preprint announcement)… 👇

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January 15, 2025 at 8:12 PM