Adeline Yong
adelineyong.bsky.social
Adeline Yong
@adelineyong.bsky.social
Synapses and activity • NINDS K99 Fellow • postdoc Jan lab UCSF • PhD Huganir lab Johns Hopkins • she/her
Reposted by Adeline Yong
New research from @igreger.bsky.social group in the LMB’s Neurobiology Division, show that GluA3 adopts a structural organization that substantially diverges from all the other AMPA receptors.

Read more: www2.mrc-lmb.cam.ac.uk/architecture...

#LMBResearch
July 1, 2025 at 3:40 PM
Reposted by Adeline Yong
Excited to share our preprint: "A Cellular Basis for Heightened Gut Sensitivity in Females."
doi.org/10.1101/2025...

We address the question: Why do women feel more gut pain? We found that estrogen boosts communication between L-cells and EC cells, triggering increased gut sensitivity.
May 29, 2025 at 7:08 PM
Reposted by Adeline Yong
Here is an article about how NIH cuts are impacting research on rare genetic disorders like autism. hub.jhu.edu/2025/05/14/r...
NIH cuts stalling progress on rare genetic disorders like SynGap1
Hopkins neuroscientist Richard Huganir is close to finding a potential life-changing treatment for kids with SYNGAP1-related disorders, but cuts to federal funding could delay or halt the progress
hub.jhu.edu
May 14, 2025 at 2:30 PM
Reposted by Adeline Yong
I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all.
time.com/7216299/nih-...
Experts Call NIH Budget Cuts an 'Apocalypse' for Science
The reductions target indirect costs that cover administrative and equipment costs.
time.com
February 15, 2025 at 9:28 PM
Reposted by Adeline Yong
Beautiful example of spatial proteomic dissection
of synapse diversity from De Wit Lab!
Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons - PubMed
Cortical layer 5 (L5) intratelencephalic (IT) and pyramidal tract (PT) neurons are embedded in distinct information processing pathways. Their morphology, connectivity, electrophysiological properties...
pubmed.ncbi.nlm.nih.gov
February 10, 2025 at 3:09 PM