Cingöz Lab
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acingozlab.bsky.social
Cingöz Lab
@acingozlab.bsky.social
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Cancer Therapy Resistance and Tumor Metabolism Lab. Istanbul.
PI: @ahmetcingoz.bsky.social

https://cingozlab.com
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ahmetcingoz.bsky.social
🎉 Excited to share that a new article led by my colleague Özlem is now online!

In this study, she explored epigenetic vulnerabilities in Taxol-resistant triple-negative breast cancer using the CRISPR and chemical screening approach. 🧬🎗️

www.nature.com/articles/s12...
Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer - Experimental & Molecular Medicine
Triple-negative breast cancer (TNBC) is a challenging type of breast cancer that lacks targeted treatment options. Researchers aimed to understand why some TNBC cells become resistant to the chemother...
www.nature.com
July 1, 2025 at 8:15 AM
acingozlab.bsky.social
"Targeting Astrocytes Could Boost Glioblastoma Treatment"
#Glioblastoma
#TRAIL

www.insideprecisionmedicine.com/topics/oncol...
Targeting Astrocytes Could Boost Glioblastoma Treatment
A subtype of astrocytes has been identified as a therapeutic target to enhance tumor immunity and extend survival in glioblastoma.
www.insideprecisionmedicine.com
May 26, 2025 at 7:56 AM
acingozlab.bsky.social
"New Research Uncovers Cellular Ecosystems and Evolutionary Paths in Glioblastoma"
www.insideprecisionmedicine.com/topics/oncol...
New Research Uncovers Cellular Ecosystems and Evolutionary Paths in Glioblastoma
Study reveals how glioblastoma evolves uniquely in each patient, offering new insight into therapy resistance and tumor growth.
www.insideprecisionmedicine.com
May 15, 2025 at 1:13 PM
acingozlab.bsky.social
May is Brain Tumor Awareness Month!
Check out this new preprint on TMZ resistance and epigenetic regulation in glioblastoma.👇🏻

#BrainTumorAwarenessMonth
#BrainTumorStrong
ahmetcingoz.bsky.social Ahmet Cingöz @ahmetcingoz.bsky.social · May 10
New preprint from my colleague Yağmur! She developed TMZ-resistant glioblastoma cells and identified key regulators using an epigenetics-focused CRISPR/Cas9 library screen. A great step towards understanding resistance mechanisms. 👏🧬🧠
#TBOLab
#BrainTumorStrong
biorxiv-cancer.bsky.social bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · May 10
Functional Genomic Screens Reveal RBBP4 as a Key Regulator of Cell Cycle Progression in TMZ-Resistant Glioblastoma https://www.biorxiv.org/content/10.1101/2025.05.09.653010v1
May 15, 2025 at 1:12 PM