André Carvalho
@abcarvalho97.bsky.social
Biochemist and Drosophilist by training.
Curious by nature!
🧑🔬 PhD student at @polarityi3s.bsky.social
🚦 RhoGTPases and Cell Division
🫁 Self-Organization from cells to tissues
⚙️Protein Structure and Design
🔬 Image Analysis and Automation
Curious by nature!
🧑🔬 PhD student at @polarityi3s.bsky.social
🚦 RhoGTPases and Cell Division
🫁 Self-Organization from cells to tissues
⚙️Protein Structure and Design
🔬 Image Analysis and Automation
Reposted by André Carvalho
Are you attending #EMBOcellPolarity25? Our postdoc @tushnakapoor.bsky.social will talk about her work on how #polarity controls #epiboly movements in #zebrafish, TOMORROW at Session 1, 11:15am! 🐟
May 18, 2025 at 2:47 PM
Are you attending #EMBOcellPolarity25? Our postdoc @tushnakapoor.bsky.social will talk about her work on how #polarity controls #epiboly movements in #zebrafish, TOMORROW at Session 1, 11:15am! 🐟
Reposted by André Carvalho
Congratulations to the McDonald lab (including @mcobbaut.bsky.social) for this work, with a small contribution from our team @abcarvalho97.bsky.social in Porto @i3suporto.bsky.social
January 7, 2025 at 2:05 PM
Congratulations to the McDonald lab (including @mcobbaut.bsky.social) for this work, with a small contribution from our team @abcarvalho97.bsky.social in Porto @i3suporto.bsky.social
How does Lgl help "control" apical-basal polarity, as a substrate of aPKC? This paper gives a much needed mechanistic insight! Featuring the important role of Cdc42 and Crumbs too. One of my favourite parts!
Congrats to Dr. @mcobbaut.bsky.social. It was wonderful collaborating with you!!
Congrats to Dr. @mcobbaut.bsky.social. It was wonderful collaborating with you!!
Excited to share our latest publication 🚨
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
Capture, mutual inhibition and release mechanism for aPKC–Par6 and its multisite polarity substrate Lgl - Nature Structural & Molecular Biology
Combining structural, biochemical, cellular and in vivo assays, the authors uncover the mechanism for capture and multisite phosphorylation of lethal (2) giant larvae by the atypical protein kinase C ...
www.nature.com
January 8, 2025 at 9:48 AM
How does Lgl help "control" apical-basal polarity, as a substrate of aPKC? This paper gives a much needed mechanistic insight! Featuring the important role of Cdc42 and Crumbs too. One of my favourite parts!
Congrats to Dr. @mcobbaut.bsky.social. It was wonderful collaborating with you!!
Congrats to Dr. @mcobbaut.bsky.social. It was wonderful collaborating with you!!
Reposted by André Carvalho
Excited to share our latest publication 🚨
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
Capture, mutual inhibition and release mechanism for aPKC–Par6 and its multisite polarity substrate Lgl - Nature Structural & Molecular Biology
Combining structural, biochemical, cellular and in vivo assays, the authors uncover the mechanism for capture and multisite phosphorylation of lethal (2) giant larvae by the atypical protein kinase C ...
www.nature.com
January 7, 2025 at 8:46 AM
Excited to share our latest publication 🚨
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
Whhhhaaaaaat 👀😯
'The discovery of the nucleosome in 1974 revealed histones’ significance in genome organization. Before this discovery, however, histones were known for their potent antimicrobial activity as antimicrobial peptides'
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Histone H1 kills MRSA
Marsman et al. detect histone H1 in MRSA in human abscesses and demonstrate that it
kills MRSA under physiological conditions. They identify through selective evolution
and a genome-wide screen that h...
www.cell.com
November 18, 2024 at 12:04 AM
Whhhhaaaaaat 👀😯