Aaron Pomerantz
@aaronpomerantz.bsky.social
Associate Director, Global Segment Marketing @ Oxford Nanopore Technologies - Microbiology, Infectious Disease, Synthetic Biology. The coolest discoveries are the ones you make. Tweets/views are my own.
Each year at @asm.org I'm blown away by the growing amount of presentations and posters leveraging @nanoporetech.com. This year we identified nearly 100 abstracts, ranging from clinical micro & public health applications to environmental research. See you there! nanoporetech.com/about/events...
June 16, 2025 at 6:53 PM
Each year at @asm.org I'm blown away by the growing amount of presentations and posters leveraging @nanoporetech.com. This year we identified nearly 100 abstracts, ranging from clinical micro & public health applications to environmental research. See you there! nanoporetech.com/about/events...
Hope you enjoyed this London Calling 2025 #NanoporeConf recap. As always, it's the people - my colleagues and the community - who make all of this possible and drive the field forward, even in challenging times
May 23, 2025 at 11:08 PM
Hope you enjoyed this London Calling 2025 #NanoporeConf recap. As always, it's the people - my colleagues and the community - who make all of this possible and drive the field forward, even in challenging times
Last but certainly not least, we're taking these applications beyond research into applied industries & biopharma, including plasmid, AAV, mRNA manufacturing and adventitious viral agent contamination, provider deeper insight & faster TAT for these critical biological materials
May 23, 2025 at 11:08 PM
Last but certainly not least, we're taking these applications beyond research into applied industries & biopharma, including plasmid, AAV, mRNA manufacturing and adventitious viral agent contamination, provider deeper insight & faster TAT for these critical biological materials
Direct RNA sequencing is also coming into the limelight for micro, highlighted by Chloé Baum at Pasteur Institute with dengue & chikungunya. Now with 24 barcodes coming for direct RNA multiplexing, this will become a critical tool for novel insights without biases of cDNA
May 23, 2025 at 11:08 PM
Direct RNA sequencing is also coming into the limelight for micro, highlighted by Chloé Baum at Pasteur Institute with dengue & chikungunya. Now with 24 barcodes coming for direct RNA multiplexing, this will become a critical tool for novel insights without biases of cDNA
Bonus post sneaking in eukaryotes! High-quality, telomere-to-telomere (T2T) assemblies have potential to set a new gold standard, but were challenging & resource intensive. That's now changing thanks to new software like hifiasm-ONT - check out these amazing assemblies in 🐝🌽🐮
May 23, 2025 at 11:08 PM
Bonus post sneaking in eukaryotes! High-quality, telomere-to-telomere (T2T) assemblies have potential to set a new gold standard, but were challenging & resource intensive. That's now changing thanks to new software like hifiasm-ONT - check out these amazing assemblies in 🐝🌽🐮
I also believe that the next frontier is Microbial Epigenomics. Detection of base modifications is best-in-class with @nanoporetech.com & the data is already right there every time you sequence a microbial sample directly without PCR. What discoveries are lurking right under our noses?
May 23, 2025 at 11:08 PM
I also believe that the next frontier is Microbial Epigenomics. Detection of base modifications is best-in-class with @nanoporetech.com & the data is already right there every time you sequence a microbial sample directly without PCR. What discoveries are lurking right under our noses?
This extends beyond microbial isolates into complex microbiomes. @sisseljuul.bsky.social and @dorylophile.bsky.social showcased beautiful benchmarking data on superior genome recovery and strain-level resolution in the ZymoBIOMICS Fecal Reference with ONT compared to alternative sequencing platforms
May 23, 2025 at 11:08 PM
This extends beyond microbial isolates into complex microbiomes. @sisseljuul.bsky.social and @dorylophile.bsky.social showcased beautiful benchmarking data on superior genome recovery and strain-level resolution in the ZymoBIOMICS Fecal Reference with ONT compared to alternative sequencing platforms
The ability to resolve closed microbial genomes & plasmids has been a critical case for long-reads, but our teams have been pushing to make ONT all you need - thanks to updates in basecalling/polishing, you now get best of both worlds: high-quality assemblies with high-accuracy
May 23, 2025 at 11:08 PM
The ability to resolve closed microbial genomes & plasmids has been a critical case for long-reads, but our teams have been pushing to make ONT all you need - thanks to updates in basecalling/polishing, you now get best of both worlds: high-quality assemblies with high-accuracy
Michael Wiley from Nebraska Public Health shared his great experience with the ElysION device on automated sample-to-answer microbial isolate WGS for hospital-acquired infections, finding that ONT served as a faster, cost-effective, accurate platform to support HAI investigations
May 23, 2025 at 11:08 PM
Michael Wiley from Nebraska Public Health shared his great experience with the ElysION device on automated sample-to-answer microbial isolate WGS for hospital-acquired infections, finding that ONT served as a faster, cost-effective, accurate platform to support HAI investigations
Our community members presented incredible ONT use cases, including Judith Breuer showcasing how rapid metagenomics is faster than standard microbiology for identifying respiratory infections & how new targeted methods increase sensitivity & speed for sterile sites www.medrxiv.org/content/10.1...
May 23, 2025 at 11:08 PM
Our community members presented incredible ONT use cases, including Judith Breuer showcasing how rapid metagenomics is faster than standard microbiology for identifying respiratory infections & how new targeted methods increase sensitivity & speed for sterile sites www.medrxiv.org/content/10.1...
One of the new kits I am personally very excited about is the Microbial Amplicon Barcoding Kit - a library prep approach for fast, flexible, full-length amplicon sequencing. If interested, please check out our registration page while we ramp production register.nanoporetech.com/microbial-am...
May 23, 2025 at 11:08 PM
One of the new kits I am personally very excited about is the Microbial Amplicon Barcoding Kit - a library prep approach for fast, flexible, full-length amplicon sequencing. If interested, please check out our registration page while we ramp production register.nanoporetech.com/microbial-am...
@rsinclairdokos.bsky.social then highlighted our maturing portfolio of End-to-End solutions in this segment, including full-length 16S/ITS, viral WGS, bacterial & fungal isolate WGS, metagenomics, & synthetic construct verification. You can check out the full tech update youtube.com/watch?v=OYql...
May 23, 2025 at 11:08 PM
@rsinclairdokos.bsky.social then highlighted our maturing portfolio of End-to-End solutions in this segment, including full-length 16S/ITS, viral WGS, bacterial & fungal isolate WGS, metagenomics, & synthetic construct verification. You can check out the full tech update youtube.com/watch?v=OYql...
Every year there so many amazing @nanoporetech.com updates at London Calling. Here I'll focus on some of my top picks for Microbiology & Infectious Disease 🦠
First, we saw how the technology continued to advance research in 2024 with ~2/3 of ONT publications in micro/infectious #nanoporeconf
First, we saw how the technology continued to advance research in 2024 with ~2/3 of ONT publications in micro/infectious #nanoporeconf
May 23, 2025 at 11:08 PM
Every year there so many amazing @nanoporetech.com updates at London Calling. Here I'll focus on some of my top picks for Microbiology & Infectious Disease 🦠
First, we saw how the technology continued to advance research in 2024 with ~2/3 of ONT publications in micro/infectious #nanoporeconf
First, we saw how the technology continued to advance research in 2024 with ~2/3 of ONT publications in micro/infectious #nanoporeconf
Advancements in T2T genomes were also highlighted by Sergey Koren at PAG, noting significant progress in
Oxford Nanopore sequencing quality as a standalone-dataset for high-quality assemblies, without need for PacBio HiFi data. Can't wait to see even further exciting updates in 2025 🌱
Oxford Nanopore sequencing quality as a standalone-dataset for high-quality assemblies, without need for PacBio HiFi data. Can't wait to see even further exciting updates in 2025 🌱
January 15, 2025 at 8:38 PM
Advancements in T2T genomes were also highlighted by Sergey Koren at PAG, noting significant progress in
Oxford Nanopore sequencing quality as a standalone-dataset for high-quality assemblies, without need for PacBio HiFi data. Can't wait to see even further exciting updates in 2025 🌱
Oxford Nanopore sequencing quality as a standalone-dataset for high-quality assemblies, without need for PacBio HiFi data. Can't wait to see even further exciting updates in 2025 🌱
Last but certainly not least, Kevin Fengler (Corteva) shared amazing progress in telomere-to-telomere (T2T) plant genome assemblies, which has has finally become a reality thanks to high-accuracy @nanoporetech.com & assembly methods such as Hifiasm, now producing better assemblies than PacBio HiFi
January 15, 2025 at 8:38 PM
Last but certainly not least, Kevin Fengler (Corteva) shared amazing progress in telomere-to-telomere (T2T) plant genome assemblies, which has has finally become a reality thanks to high-accuracy @nanoporetech.com & assembly methods such as Hifiasm, now producing better assemblies than PacBio HiFi
Eugenie 'Charley' Yen (Queen Mary U of London) then shared her beautiful work using Oxford Nanopore sequencing for genomic & epigenomic approaches for conservation of endangered loggerhead sea turtles - even taking the P2 device into the field to deploy methylation-based biomarkers in real-time!
January 15, 2025 at 8:38 PM
Eugenie 'Charley' Yen (Queen Mary U of London) then shared her beautiful work using Oxford Nanopore sequencing for genomic & epigenomic approaches for conservation of endangered loggerhead sea turtles - even taking the P2 device into the field to deploy methylation-based biomarkers in real-time!
Next, we had Andrew Lail (O'Connor Lab, U Wisconsin-Madison) share their important work developing methods to enhance H5N1 genomic surveillance by sequencing milk samples, noting how Oxford Nanopore is a useful as a faster, efficient method over short-read platforms for timely avian influenza WGS
January 15, 2025 at 8:38 PM
Next, we had Andrew Lail (O'Connor Lab, U Wisconsin-Madison) share their important work developing methods to enhance H5N1 genomic surveillance by sequencing milk samples, noting how Oxford Nanopore is a useful as a faster, efficient method over short-read platforms for timely avian influenza WGS
First up during our Industry Workshop, Sean Prosser (U Guelph) demonstrated how @nanoporetech.com can be used to sequence >100,000 specimens at once, lowering cost to just $0.01 each, with even a MinION outperforming a PacBio Sequel II. Incredibly, they now do >1M specimens at once on a PromethION!
January 15, 2025 at 8:38 PM
First up during our Industry Workshop, Sean Prosser (U Guelph) demonstrated how @nanoporetech.com can be used to sequence >100,000 specimens at once, lowering cost to just $0.01 each, with even a MinION outperforming a PacBio Sequel II. Incredibly, they now do >1M specimens at once on a PromethION!
There were remarkable updates presented at #PAG32 on incredibly accurate @nanoporetech.com sequencing for applications ranging from telomere-to-telomere plant & animal genome assemblies, to amplicon sequencing at massive scale. Here are some highlights in case you missed them (thread)
January 15, 2025 at 8:38 PM
There were remarkable updates presented at #PAG32 on incredibly accurate @nanoporetech.com sequencing for applications ranging from telomere-to-telomere plant & animal genome assemblies, to amplicon sequencing at massive scale. Here are some highlights in case you missed them (thread)
