There's increasing evidence that in organoid/embryoids conditions of cells at start of experiments is crucial/ determines outcome. Much to be learnt still. Taking advantage of mouse #gastruloids, two groups explore this here. Important work to calibrate the field www.biorxiv.org/content/10.1...

Really happy to share our article published in Development (journals.biologists.com/dev/issue/15...)! This is a true collaborative effort with @etche.bsky.social e.bsky.social and @alainchedotal.bsky.social chedotal.bsky.social. This work was supported by the HuDeCA program from @inserm.fr

Using #gastruloids F. Lescroart and colleagues explore the origins of the most complex organ in our body, the #heart. Very good start of unravelling an amazing process in which an organ is being designed and redesigned at the same time it functions
www.nature.com/articles/s41...