Zach
@zacharywalker.bsky.social
Asst Research Professor at University of Colorado, focused on therapy development for multiple myeloma.
The latest research from our lab - utilizing ribosome profiling to investigate mechanisms of drug resistance in multiple myeloma: aacrjournals.org/mcr/article-...
Ribosome Profiling Reveals Translational Reprogramming via mTOR Activation in Omacetaxine-Resistant Multiple Myeloma
Abstract. Protein homeostasis is critical to the survival of multiple myeloma cells. Although this is targeted with proteasome inhibitors, mRNA translation inhibition has not entered trials. Recent wo...
aacrjournals.org
May 19, 2025 at 8:29 PM
The latest research from our lab - utilizing ribosome profiling to investigate mechanisms of drug resistance in multiple myeloma: aacrjournals.org/mcr/article-...
Should patients with high-risk smoldering myeloma receive daratumumab? #MyelomaSky www.nejm.org/doi/full/10....
Daratumumab or Active Monitoring for High-Risk Smoldering Multiple Myeloma | NEJM
Daratumumab, an anti-CD38 monoclonal antibody, has been approved for the treatment
of multiple myeloma. Data are needed regarding the use of daratumumab for high-risk
smoldering multiple myeloma, a...
www.nejm.org
December 14, 2024 at 6:11 PM
Should patients with high-risk smoldering myeloma receive daratumumab? #MyelomaSky www.nejm.org/doi/full/10....
Reposted by Zach
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 29, 2024 at 8:04 PM
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Interesting approach to ex vivo drug screening in AML, out this week in Cancer Medicine: A Combinatorial Functional Precision Medicine Platform for Rapid Therapeutic Response Prediction in AML
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
A Combinatorial Functional Precision Medicine Platform for Rapid Therapeutic Response Prediction in AML
The Quadratic Phenotypic Optimization Platform (QPOP) allows for the analysis of patient-specific combinatorial drug sensitivities without prior genetic testing in a rapid manner compared to standard...
onlinelibrary.wiley.com
November 23, 2024 at 3:10 PM
Interesting approach to ex vivo drug screening in AML, out this week in Cancer Medicine: A Combinatorial Functional Precision Medicine Platform for Rapid Therapeutic Response Prediction in AML
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Zach
What an achievement vaccines are. What a monument to our love for each other it is to stare straight into the face of something as horrific and unstoppable as smallpox or measles or polio or cervical cancer and say “You know what, it doesn’t have to be like this.”
HUMANS!
HUMANS!
November 15, 2024 at 1:59 AM
What an achievement vaccines are. What a monument to our love for each other it is to stare straight into the face of something as horrific and unstoppable as smallpox or measles or polio or cervical cancer and say “You know what, it doesn’t have to be like this.”
HUMANS!
HUMANS!