Type VI Sophia System
@wheezenfeld.bsky.social
Former Vibrio, current System Biology PhD candidate in Michael Baym's Lab at Harvard Medical School. she/her
"The agreement of the results seems to show that light and magnetism are affections of the same substance" (James Maxwell 1865)
"The agreement of the results seems to show that light and magnetism are affections of the same substance" (James Maxwell 1865)
Pinned
Loved having a chance this weekend to showcase the science behind bioluminescence & talk about the bioluminescent bays of Puerto Rico at the Harvard Museum's Celebremos Puerto Rico 🕺🇵🇷!
September 30, 2025 at 3:57 PM
Loved having a chance this weekend to showcase the science behind bioluminescence & talk about the bioluminescent bays of Puerto Rico at the Harvard Museum's Celebremos Puerto Rico 🕺🇵🇷!
Really cool work on anthropomorphic driven change of plasmids :)!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
September 26, 2025 at 3:54 PM
Really cool work on anthropomorphic driven change of plasmids :)!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Very relatable stuff from President Garber, this is how I feel learning that the incoming freshmen were probably all born in 2007
September 2, 2025 at 10:42 PM
Very relatable stuff from President Garber, this is how I feel learning that the incoming freshmen were probably all born in 2007
This is one of the findings that really motivates my research: yes, antibiotic resistance genes are ancient, but the age of antibiotics has likely contributed to a big change in their mobility and of the landscape of MGEs we see today! Very happy for Arya and to see this published.
September 2, 2025 at 10:30 PM
This is one of the findings that really motivates my research: yes, antibiotic resistance genes are ancient, but the age of antibiotics has likely contributed to a big change in their mobility and of the landscape of MGEs we see today! Very happy for Arya and to see this published.
broke: the professor writing professor x grad student romance novels
woke: the PhD student writing about a student going to Hell to bring her PI back from the dead bc he hadn’t finished writing her rec letter
woke: the PhD student writing about a student going to Hell to bring her PI back from the dead bc he hadn’t finished writing her rec letter
August 26, 2025 at 11:29 PM
broke: the professor writing professor x grad student romance novels
woke: the PhD student writing about a student going to Hell to bring her PI back from the dead bc he hadn’t finished writing her rec letter
woke: the PhD student writing about a student going to Hell to bring her PI back from the dead bc he hadn’t finished writing her rec letter
Reposted by Type VI Sophia System
Have you ever wondered what increasing environmental stress will do to microbial communities?
In our new preprint, @martinadalbello.bsky.social, Jeff Gore and I studied the impact of salinity on microbial community composition and function. 🧵 (1/5)
www.biorxiv.org/content/10.1...
In our new preprint, @martinadalbello.bsky.social, Jeff Gore and I studied the impact of salinity on microbial community composition and function. 🧵 (1/5)
www.biorxiv.org/content/10.1...
Microbial communities demonstrate robustness in stressful environments due to predictable composition shifts
Environmental stress reduces species growth rates, but its impact on the function of microbial communities is less clear. Here, we experimentally demonstrate that increasing salinity stress shifts com...
www.biorxiv.org
August 25, 2025 at 2:33 PM
Have you ever wondered what increasing environmental stress will do to microbial communities?
In our new preprint, @martinadalbello.bsky.social, Jeff Gore and I studied the impact of salinity on microbial community composition and function. 🧵 (1/5)
www.biorxiv.org/content/10.1...
In our new preprint, @martinadalbello.bsky.social, Jeff Gore and I studied the impact of salinity on microbial community composition and function. 🧵 (1/5)
www.biorxiv.org/content/10.1...
Proud to announce I got this new piece of paper !!! (And also finished my Bok teaching certif)
For the past 3 years I’ve done coursework, teaching observations & made a portfolio to try to become a better TF. It’s been amazing so far and I’m excited to teach Integrated Science again this spring :)
For the past 3 years I’ve done coursework, teaching observations & made a portfolio to try to become a better TF. It’s been amazing so far and I’m excited to teach Integrated Science again this spring :)
August 15, 2025 at 1:53 AM
Proud to announce I got this new piece of paper !!! (And also finished my Bok teaching certif)
For the past 3 years I’ve done coursework, teaching observations & made a portfolio to try to become a better TF. It’s been amazing so far and I’m excited to teach Integrated Science again this spring :)
For the past 3 years I’ve done coursework, teaching observations & made a portfolio to try to become a better TF. It’s been amazing so far and I’m excited to teach Integrated Science again this spring :)
We will miss you Hue!!!
When I was told I’d have a summer undergrad I couldn’t have imagined how lucky I would be. Hue has no tolerance for the easy way out and takes on new challenges with an infectious positivity. One day (hopefully🤞) someone will be just as lucky to have her as a grad student. We will miss you!
August 8, 2025 at 7:13 PM
We will miss you Hue!!!
Last week with our summer undergrads 🥲💔 SPECTACULAR students and we will all miss them immensely. Summer research experiences are (for me) one of the most rewarding parts of being in academia so I am really praying that they will continue to be a learning opportunity for mentors and mentees alike
August 8, 2025 at 2:56 PM
Last week with our summer undergrads 🥲💔 SPECTACULAR students and we will all miss them immensely. Summer research experiences are (for me) one of the most rewarding parts of being in academia so I am really praying that they will continue to be a learning opportunity for mentors and mentees alike
Getting powerpoint alt text to summarize my PhD (colorful image of a long line)
July 1, 2025 at 3:14 AM
Getting powerpoint alt text to summarize my PhD (colorful image of a long line)
Reposted by Type VI Sophia System
1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬
www.science.org/doi/full/10....
www.science.org/doi/full/10....
June 24, 2025 at 4:52 PM
1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬
www.science.org/doi/full/10....
www.science.org/doi/full/10....
the Baym lab 🔜 Molecular Mechanisms GRS! Come talk about the evolution and ecology of MGEs
@fernpizza.bsky.social Multilevel plasmid selection!
@arya (arya.casa) Creation of deletion-born fusion genes (frankenstein genes 🧟)
@theshreyaspai.bsky.social Why sex is so common even though it’s costly
@fernpizza.bsky.social Multilevel plasmid selection!
@arya (arya.casa) Creation of deletion-born fusion genes (frankenstein genes 🧟)
@theshreyaspai.bsky.social Why sex is so common even though it’s costly
June 21, 2025 at 4:58 PM
the Baym lab 🔜 Molecular Mechanisms GRS! Come talk about the evolution and ecology of MGEs
@fernpizza.bsky.social Multilevel plasmid selection!
@arya (arya.casa) Creation of deletion-born fusion genes (frankenstein genes 🧟)
@theshreyaspai.bsky.social Why sex is so common even though it’s costly
@fernpizza.bsky.social Multilevel plasmid selection!
@arya (arya.casa) Creation of deletion-born fusion genes (frankenstein genes 🧟)
@theshreyaspai.bsky.social Why sex is so common even though it’s costly
Day 1 of PhD vs. Day 1000
June 19, 2025 at 9:30 PM
Day 1 of PhD vs. Day 1000
I just called my congress members (www.congress.gov/members/find...). 5calls and Chop Wood, Carry Water have good scripts if you are not sure what to say.
May 31, 2025 at 8:56 PM
I just called my congress members (www.congress.gov/members/find...). 5calls and Chop Wood, Carry Water have good scripts if you are not sure what to say.
Reposted by Type VI Sophia System
I'll also add: all five federal grants that supported different parts this work were part of the mass termination of Harvard grants three weeks ago
May 29, 2025 at 2:21 AM
I'll also add: all five federal grants that supported different parts this work were part of the mass termination of Harvard grants three weeks ago
Reposted by Type VI Sophia System
Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/...
Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
May 28, 2025 at 10:34 PM
Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/...
Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
Phage DisCo is out in mSystems!! Super useful (and beautiful) method for targeted phage discovery for your every need :)
Phage DisCo can be further multiplexed with three bacterial strains in co-culture, and, when tested with characterized phages, the fluorescent signal shined! Maybe you can see where the disco ball comparison comes in here. 🪩 4/
May 29, 2025 at 7:04 PM
Phage DisCo is out in mSystems!! Super useful (and beautiful) method for targeted phage discovery for your every need :)
HUGE celebration moment, on Friday @ellie-rand.bsky.social defended her PhD!! Took a lot of determination✨ but it was awesome to see and I am so proud of the newly titled Dr Rand :)
April 28, 2025 at 2:01 PM
HUGE celebration moment, on Friday @ellie-rand.bsky.social defended her PhD!! Took a lot of determination✨ but it was awesome to see and I am so proud of the newly titled Dr Rand :)
Reposted by Type VI Sophia System
Why is sex so common if it's so costly?
Super excited to share our new preprint “Sex decreases the pleiotropic costs of local adaptation”, where we bring a new angle to this age-old evolutionary question. Co-led by Parris Humphrey, in Michael Desai's lab. Short thread here: (1/n)
Super excited to share our new preprint “Sex decreases the pleiotropic costs of local adaptation”, where we bring a new angle to this age-old evolutionary question. Co-led by Parris Humphrey, in Michael Desai's lab. Short thread here: (1/n)
Sex decreases the pleiotropic costs of local adaptation https://www.biorxiv.org/content/10.1101/2025.03.28.646016v1
April 2, 2025 at 6:59 PM
Why is sex so common if it's so costly?
Super excited to share our new preprint “Sex decreases the pleiotropic costs of local adaptation”, where we bring a new angle to this age-old evolutionary question. Co-led by Parris Humphrey, in Michael Desai's lab. Short thread here: (1/n)
Super excited to share our new preprint “Sex decreases the pleiotropic costs of local adaptation”, where we bring a new angle to this age-old evolutionary question. Co-led by Parris Humphrey, in Michael Desai's lab. Short thread here: (1/n)
azenta genewiz, instead of releasing longread plasmid sequencing, has released wizard trading cards and i am genuinely at a loss for words
April 3, 2025 at 2:42 PM
azenta genewiz, instead of releasing longread plasmid sequencing, has released wizard trading cards and i am genuinely at a loss for words
I do not know Michael Baym
April 1, 2025 at 6:11 PM
I do not know Michael Baym
Every pioneer or prophet must suffer
April 1, 2025 at 6:11 PM
Every pioneer or prophet must suffer
Sci-fi movies are misleading people
April 1, 2025 at 6:10 PM
Sci-fi movies are misleading people
Woolly mice is bioweapon.
April 1, 2025 at 6:09 PM
Woolly mice is bioweapon.
Reposted by Type VI Sophia System
