Tony Kelly
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tonykellyeu.bsky.social
Tony Kelly
@tonykellyeu.bsky.social
Bringing deep neuroscience and epilepsy domain expertise to data science
Recently I referred to how dendritic compartmentalisation increases computation.
What is a computational unit. How has the view evolved from point neuron (basis for ANNs). How a neuroscience view may increase AI efficiency.
buff.ly/zoF1rJz
preprint on compartmentalisation buff.ly/TAsJuVr
September 2, 2025 at 3:33 PM
Dendrites have been under the microscope, since 1888. We took it further and put dendrites under 3 different microscopes (ExM, STED, EM) and reconstructed entire branches to reveal fine nanoscale details. #SuperResolution #ElectronMicroscopy #Morphology
https://doi.org/10.1101/2025.07.18.664460
August 30, 2025 at 8:14 PM
Very happy our cautionary tale of GECI expression in the hippocampus is out in @eLife.
https://elifesciences.org/articles/93804
We describe Ca2+ waves though the hippocampus. Mesmerising but artefact of GECI expression.
Also a tweet print https://x.com/tonykellyEU/status/1723654794626154891. 1/3
August 30, 2025 at 8:14 PM
Our @eLife paper on artefactual Ca2+ waves following calcium indicator expression is highlighted in neuroscience magazine @_TheTransmitter. Really nice talking with @avaskham and seeing the perspectives from @Sheffield_Lab, @DanielDombeck & @LoogerL https://t.co/vqy9K5hEeP
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
www.thetransmitter.org
August 30, 2025 at 8:13 PM
Nice work on how differences in dendritic morphology btwn human and mouse neurons impact dendritic excitability. https://x.com/GregStuartLab/status/1602900777328332800
August 30, 2025 at 8:12 PM