Johnny Yu
@thejohnnyyu.bsky.social
CSO & co-founder at vevo.ai | Former UCSF, Goodarzi Lab, Broad, Biogen
Reposted by Johnny Yu
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling
Building predictive models of the cell requires systematically mapping how perturbations reshape each cell's state, function, and behavior. Here, we present Tahoe-100M, a giga-scale single-cell atlas ...
www.biorxiv.org
February 25, 2025 at 1:25 PM
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Reposted by Johnny Yu
This was all made possible by the Mosaic platform! What is Mosaic? @thejohnnyyu.bsky.social took his work in our lab, and scaled it in every dimension… Mosaic brings a highly diversified, exquisitely optimized, and optimally balanced “cell village” approach to perturbation data collection.
February 25, 2025 at 1:25 PM
This was all made possible by the Mosaic platform! What is Mosaic? @thejohnnyyu.bsky.social took his work in our lab, and scaled it in every dimension… Mosaic brings a highly diversified, exquisitely optimized, and optimally balanced “cell village” approach to perturbation data collection.
Reposted by Johnny Yu
If you are intrigued by this, and if you're working on AI/ML, single-cell biology, or drug discovery, I urge y’all to reach out to @thejohnnyyu.bsky.social, @therealnima.bsky.social or any of the @vevotherapeutics.bsky.social team. www.prnewswire.com/news-release...
Vevo Therapeutics Open Sources Tahoe-100M, the World's Largest Single-Cell Dataset, as the Inaugural Contribution to Arc Institute's New Virtual Cell Atlas
/PRNewswire/ -- In a landmark move to advance AI-driven biological research, Arc Institute and Vevo Therapeutics announced today that they have partnered on...
www.prnewswire.com
February 25, 2025 at 1:25 PM
If you are intrigued by this, and if you're working on AI/ML, single-cell biology, or drug discovery, I urge y’all to reach out to @thejohnnyyu.bsky.social, @therealnima.bsky.social or any of the @vevotherapeutics.bsky.social team. www.prnewswire.com/news-release...
Reposted by Johnny Yu
Watch @thejohnnyyu.bsky.social @therealnima.bsky.social (@vevotherapeutics.bsky.social), @pdhsu.bsky.social , Dave Burke and I (@arcinstitute.org) talking about virtual cells, and how #Tahoe100M, now on. @arcinstitute.org's Virtual Cell Atlas, can change the game!
www.youtube.com/watch?v=ak_f...
www.youtube.com/watch?v=ak_f...
No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
YouTube video by No Priors: AI, Machine Learning, Tech, & Startups
www.youtube.com
February 25, 2025 at 1:39 PM
Watch @thejohnnyyu.bsky.social @therealnima.bsky.social (@vevotherapeutics.bsky.social), @pdhsu.bsky.social , Dave Burke and I (@arcinstitute.org) talking about virtual cells, and how #Tahoe100M, now on. @arcinstitute.org's Virtual Cell Atlas, can change the game!
www.youtube.com/watch?v=ak_f...
www.youtube.com/watch?v=ak_f...
Reposted by Johnny Yu
Our latest from the indefatigable @thejohnnyyu.bsky.social in collaboration with Weissman and Shokat labs. Meet GENEVA, which enables simultaneous phenotyping and profiling of cancer cell drug responses at scale; both in vitro and in vivo across a variety of models: www.biorxiv.org/content/10.1...
Multiplexed mosaic tumor models reveal natural phenotypic variations in drug response within and between populations
Many agents that show promise in preclinical cancer models lack efficacy in patients due to patient heterogeneity that is not captured in traditional assays. To address this problem, we have developed...
www.biorxiv.org
December 17, 2024 at 8:16 PM
Our latest from the indefatigable @thejohnnyyu.bsky.social in collaboration with Weissman and Shokat labs. Meet GENEVA, which enables simultaneous phenotyping and profiling of cancer cell drug responses at scale; both in vitro and in vivo across a variety of models: www.biorxiv.org/content/10.1...
Reposted by Johnny Yu
scRNA-seq data sets exploding in number and size - check out scanpy & anndata for >1b cells: new experimental update includes APIs for scaling with dask from anndata, integrated with lots of scanpy and rapids-singlecell functions.
gist.github.com/ilan-gold/98...
gist.github.com/ilan-gold/98...
December 11, 2024 at 3:48 PM
scRNA-seq data sets exploding in number and size - check out scanpy & anndata for >1b cells: new experimental update includes APIs for scaling with dask from anndata, integrated with lots of scanpy and rapids-singlecell functions.
gist.github.com/ilan-gold/98...
gist.github.com/ilan-gold/98...
Reposted by Johnny Yu
@thejohnnyyu.bsky.social, @therealnima.bsky.social
, Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t
, Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t
Vevo Therapeutics to Release World's Largest Atlas of Single-Cell Transcriptomic Data, Tahoe-100M, to Map How Drugs Impact Patient Cells and Accelerate Discovery of New Drugs
/PRNewswire/ -- Vevo Therapeutics, a biotechnology company using its Mosaic technology and next generation AI to uncover better drugs for more patients,...
www.prnewswire.com
December 5, 2024 at 2:25 PM
@thejohnnyyu.bsky.social, @therealnima.bsky.social
, Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t
, Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t