Tatsuo Fukagawa
@tatsuofukagawa.bsky.social
Cell Biologist, Centromere, Kinetochore
Our new paper was just out. CRISPR screening with a CENP-C mutant reveals that KIF18A and CENP-E are coordinately involved in chromosome congression. We also find that cancer cells with low levels of CENP-E are sensitive for KIF18A inhibition. Congrats Jiahang Miao!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C
Miao et al. demonstrate that KIF18A depletion causes synthetic defects with CENP-C
hypomorphic mutant and KIF18A functions for chromosome congression in cooperation
with CENP-E. CENP-E levels at kinet...
www.cell.com
November 10, 2025 at 10:05 PM
Our new paper was just out. CRISPR screening with a CENP-C mutant reveals that KIF18A and CENP-E are coordinately involved in chromosome congression. We also find that cancer cells with low levels of CENP-E are sensitive for KIF18A inhibition. Congrats Jiahang Miao!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
I just started Bluesky.
December 3, 2024 at 5:59 AM
I just started Bluesky.