Synthesis Journal
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synthesis1969.bsky.social
Synthesis Journal
@synthesis1969.bsky.social
An international, peer-reviewed Thieme journal in #chemicalsynthesis, founded in 1969, publishing #reviews and #fullpapers.

🔗 https://www.thieme.de/synthesis/journal-information-55920.htm
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Are you advancing the science of Synthetic #Chemistry? SYNTHESIS is the home for your research.

Why publish with SYNTHESIS?

🌟 Established Reputation
📈 High Readership
🥇 Annual Best Paper Award
...and more!

Have your work seen by a global audience.
Submit today: buff.ly/BZkKnCO
✨Special Topic Dedicated To Prof. Paul Knochel✨

Dirk Trauner @dirktrauner.bsky.social & team use their synthetic azide-based platform to access loline analogues and explore loline as a bidentate ligand for Pd chemistry
#ClickChemistry

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7
February 4, 2026 at 8:00 AM
Reposted by Synthesis Journal
Synthesis of Transition-Metal–Boryl Complexes from Diboron Reagents (@synthesis1969.bsky.social): www.thieme-connect.com/products/ejo....
February 3, 2026 at 10:40 AM
Diving into TM–boryl chemistry✨ Hairong Lyu & co-workers review transition-metal–boryl complexes from Fe, Co, Ni, Cu, Rh, Ir, Ru, and Pt, highlighting their formation from various diboron reagents, reactivity with alkenes/alkynes and roles in catalytic #borylation⚗️

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February 2, 2026 at 8:01 AM
✨Special Topic Dedicated To Prof. Paul Knochel✨

Exploring C–O bond #functionalization 🚀 This review by Seki & Nakao categorizes C(sp²) and C(sp³) activations, highlighting new #TransitionMetals and dual #catalysis strategies to break inert bonds⛓️

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7
January 30, 2026 at 8:01 AM
Controlling epoxide #cyclizations like never before🌀
Vanderwal & co-workers explore α-alkoxy #epoxides in Nugent–RajanBabu reductive cyclizations, revealing how α-oxygen protecting group size dictates 6-endo vs 5-exo outcomes⚗️
#TotalSynthesis

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January 28, 2026 at 8:01 AM
✨Special Topic Dedicated To Prof. Paul Knochel✨

Explore the first continuous-flow Reformatsky-type reaction via ethyl γ-bromocrotonate🚀 André B. Charette & team optimize γ-selectivity to synthesize homoallylic alcohols and #Piperine 🌿
#FlowChemistry

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7
January 26, 2026 at 8:01 AM
✨Special Topic Dedicated to Prof. Knochel ✨

Radical chemistry for remote C–C & C–heteroatom bond formation🔬 This review by Dagousset et al. highlights decades of advances in functionalizing α,β-unsaturated carbonyls🌟
#photocatalysis #organocatalysis

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7
January 23, 2026 at 8:01 AM
A mild & efficient route to trisubstituted methanes✨Waghmode & co-workers report a TFA-catalyzed, highly regioselective 1,6-addition of mercapto- and hydroxy-pyridines to para-quinone methides, offering broad scope and chromatography-free workup⚗️
#mercaptopyridine

👉 buff.ly/sOo9824
January 21, 2026 at 8:01 AM
Reposted by Synthesis Journal
Quisqualic acid is an interesting non-proteinogenic amino acid with applications in medicinal chemistry. Have a look at our detailed account on its synthesis, which was just published in Synthesis @synthesis1969.bsky.social
www.thieme-connect.de/products/ejo...
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January 20, 2026 at 5:51 PM
✨Special Topic Dedicated to Prof. Knochel ✨

Self-assembling pyridone #phosphorus ligands🧩 Bernhard Breit & co-workers present 19 ligands, including 11 P-stereogenic versions with excellent ee and high thermal stability🔥
#catalysis

#OpenAccess for a limited time 👉 buff.ly/KRqDfG7
January 19, 2026 at 8:00 AM
Michalak & Vanderwal report a clever, Cl-guided stereocontrolled formal synthesis of Steviol — using a removable chlorine center and epoxide-initiated bicyclization for precise stereochemistry🔄⚗️
#terpenoids #TotalSynthesis

👉 buff.ly/Q2ize6T
January 16, 2026 at 8:01 AM
Explore the power of π–π #interactions ! Jeonghyo Lee & co-workers show how these forces guide chemo-, regio-, and stereoselective transformations in C–C, C–O, and C–N bond formation, plus selective reductions ⚗️

👉 buff.ly/r7n7m9d
January 14, 2026 at 8:01 AM
Reposted by Synthesis Journal
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Thieme Launches New Open Access Journal Therapeutics NOW
Thieme Launches New Open Access Journal Therapeutics NOW Stuttgart, January 2026 – Thieme is expanding its open access portfolio to promote evidence-based therapeutic development. Therapeutics NOW wil...
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January 12, 2026 at 11:31 AM
Alessandro Palmieri & co-workers present a practical #onepot route to 2,5-disubstituted thiophenes, using a base-promoted Michael addition followed by acid-driven cyclization. Efficient, elegant chemistry in action!⚗️
#thiophene #nitroalkenes

👉 buff.ly/kr1FKgp
January 12, 2026 at 8:01 AM
We are pleased to welcome Prof. Akkattu T. Biju (Indian Institute of Science) as a new Associate Editor of SYNTHESIS!🎉
A leader in NHC organocatalysis and strain-release chemistry, he strengthens the journal’s Editorial Board with his outstanding expertise!

🔗 buff.ly/CjcPSsC
January 9, 2026 at 8:01 AM
We are excited to welcome Prof. Martin Oestreich @silicon-martin.bsky.social (TU Berlin) as the new Editor-in-Chief of SYNTHESIS!🎉
Martin, a leader in silicon chemistry and catalysis, looks forward to building on the journal’s success and driving its growth!

Editorial Board Focus 🔗 buff.ly/RAxs5jY
January 7, 2026 at 8:01 AM
After 20+ years on the Synthesis Editorial Board —first as Editor, then EiC— we thank Prof. Mark Lautens @marklautens.bsky.social for his incredible contributions and leadership💐 Your impact on the journal and chemistry community is lasting. Wishing you all the best! 🌟

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January 5, 2026 at 8:01 AM
🏆TOP 5 Most Downloaded Articles of 2025!
Efficient synthesis of #salicylaldehydes via the Casnati–Skattebøl reaction 🧪 Using milder, less toxic reagents to access biologically active targets—review by Douglas Klumpp and co-workers.
#formylation #phenols

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January 2, 2026 at 8:00 AM
🏆TOP 5 Most Downloaded Articles of 2025!
Crystalline perfluorinated #trityl cations have finally been isolated💎See how these powerful #Lewisacids are driving innovation in organic synthesis in the review by Gong and Mulks @ffmulks.bsky.social
#carbocation

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January 1, 2026 at 9:01 AM
✨ Cheers to 2026! ✨
The SYNTHESIS team wishes you a year full of exciting discoveries, joy, and continued success🥂🔬
January 1, 2026 at 8:01 AM
🏆TOP 5 Most Downloaded Articles of 2025!
First photocatalytic radical C(sp)–B bond formation🧪Stable alkynylated amine-boranes from boryl radicals and alkynyl sulfones, with regioselectivity guided by DFT studies in our paper by Javier Corpas et al.
#boron

#OpenAccess 👉 buff.ly/wI1JX2l
December 31, 2025 at 8:01 AM
🏆TOP 5 Most Downloaded Articles of 2025!
Carbamoyl #fluorides —an emerging frontier in organofluorine chemistry✨Explore their unique reactivity in this short review by Maryam Jabbarpoor and Christine Le @christinemle.bsky.social @leresearchgroup.bsky.social

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December 30, 2025 at 8:00 AM
🏆TOP 5 Most Downloaded Articles of 2025!
Explore modern #thioether synthesis 🧪—safer, cost-effective strategies using sulfinates as thiol surrogates, including cross-coupling and C–H activation. Review by Lam and Ma.
#thioetherification

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December 29, 2025 at 8:05 AM
Reposted by Synthesis Journal
Our last paper of the year: Electrophilic C(sp2)−H Borylation of Nonactivated Arenes with Pyramidal Boron Lewis Superacids ❄️. Just published in @synthesis1969.bsky.social : special issue dedicated to Paul Knochel. 🎁 @boron-chemistry.bsky.social. Congrats Nicolas, Arnaud & Baptiste.
December 27, 2025 at 10:36 PM
🌍 Our Team Around the World in 2025!
From Switzerland 🇨🇭 and the UK 🇬🇧, to Spain 🇪🇸, China 🇨🇳, Japan 🇯🇵, and India 🇮🇳, we shared insights, learned from peers, and celebrated innovations in #OrganicChemistry.
A huge thanks to everyone we met along the way!

2026 coming up: buff.ly/Ao26uvJ
Conferences - Thieme Chemistry - Georg Thieme Verlag
Meet the Thieme Chemistry team at conferences worldwide and find out more about our event cooperations.
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December 26, 2025 at 8:00 AM