Synthesis Journal
@synthesis1969.bsky.social
An international, peer-reviewed Thieme journal in #chemicalsynthesis, founded in 1969, publishing #reviews and #fullpapers.
🔗 https://www.thieme.de/synthesis/journal-information-55920.htm
🔗 https://www.thieme.de/synthesis/journal-information-55920.htm
Pinned
Are you advancing the science of Synthetic #Chemistry? SYNTHESIS is the home for your research.
Why publish with SYNTHESIS?
🌟 Established Reputation
📈 High Readership
🥇 Annual Best Paper Award
...and more!
Have your work seen by a global audience.
Submit today: buff.ly/BZkKnCO
Why publish with SYNTHESIS?
🌟 Established Reputation
📈 High Readership
🥇 Annual Best Paper Award
...and more!
Have your work seen by a global audience.
Submit today: buff.ly/BZkKnCO
Explore the #gold standard in #catalysis! Dive into our review by Long Li & co-workers on gold-catalyzed asymmetric #alkyne transformations, from ligand engineering to central-to-axial conversions. Discover new paths in #chirality & sustainable synthesis✨
👉 buff.ly/z0wMqw9
👉 buff.ly/z0wMqw9
November 10, 2025 at 8:01 AM
Explore the #gold standard in #catalysis! Dive into our review by Long Li & co-workers on gold-catalyzed asymmetric #alkyne transformations, from ligand engineering to central-to-axial conversions. Discover new paths in #chirality & sustainable synthesis✨
👉 buff.ly/z0wMqw9
👉 buff.ly/z0wMqw9
#Organosodium reagents are emerging as greener, more reactive alternatives to lithium🧪 Benzyl sodium shows divergent reactivity with #pyridines, unlocking access to #dihydropyridines 🔍 New mechanistic insights revealed by Eva Hevia & co-workers @evaheviagroup.bsky.social
👉 buff.ly/DThXVcG
👉 buff.ly/DThXVcG
November 7, 2025 at 8:01 AM
#Organosodium reagents are emerging as greener, more reactive alternatives to lithium🧪 Benzyl sodium shows divergent reactivity with #pyridines, unlocking access to #dihydropyridines 🔍 New mechanistic insights revealed by Eva Hevia & co-workers @evaheviagroup.bsky.social
👉 buff.ly/DThXVcG
👉 buff.ly/DThXVcG
Reposted by Synthesis Journal
🚀 Countdown to SCNOW Virtual Summit, 6–7 Nov! 🌱♻️
Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.
💻 Register NOW: cassyni.com/s/scnow-virt...
#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.
💻 Register NOW: cassyni.com/s/scnow-virt...
#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
October 28, 2025 at 11:21 AM
🚀 Countdown to SCNOW Virtual Summit, 6–7 Nov! 🌱♻️
Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.
💻 Register NOW: cassyni.com/s/scnow-virt...
#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.
💻 Register NOW: cassyni.com/s/scnow-virt...
#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
🔎 Isocyanoalkenes, an underexplored class of #isocyanides , are unlocking new paths in heterocycle synthesis🌱From biosynthesis to reactivity (conjugate & radical additions), this review by Huan Tian & Fraser Fleming highlights their vast synthetic potential🧪
👉 buff.ly/tJWJ5Z4
👉 buff.ly/tJWJ5Z4
November 5, 2025 at 8:01 AM
🔎 Isocyanoalkenes, an underexplored class of #isocyanides , are unlocking new paths in heterocycle synthesis🌱From biosynthesis to reactivity (conjugate & radical additions), this review by Huan Tian & Fraser Fleming highlights their vast synthetic potential🧪
👉 buff.ly/tJWJ5Z4
👉 buff.ly/tJWJ5Z4
Discover how chiral Pd complexes enable enantioselective #SuzukiMiyaura reactions with chain-walking🚀 A new path to pharmaceutically relevant, enantiomerically enriched targets by James Morken & co-workers✨
#organoboron #catalysis
👉 buff.ly/6YZ2sko
#organoboron #catalysis
👉 buff.ly/6YZ2sko
November 3, 2025 at 8:01 AM
Discover how chiral Pd complexes enable enantioselective #SuzukiMiyaura reactions with chain-walking🚀 A new path to pharmaceutically relevant, enantiomerically enriched targets by James Morken & co-workers✨
#organoboron #catalysis
👉 buff.ly/6YZ2sko
#organoboron #catalysis
👉 buff.ly/6YZ2sko
#Morpholine amides take the spotlight🌟 Yohei Ogiwara reviews their unique reactivity & chemoselectivity in ketone, aldehyde & acylsilane synthesis🧪 Applications include natural product synthesis, Vilsmeier–Haack reactions & polymer recycling!
#OpenAccess 👉 buff.ly/34Wm4nT
#OpenAccess 👉 buff.ly/34Wm4nT
October 31, 2025 at 8:01 AM
#Morpholine amides take the spotlight🌟 Yohei Ogiwara reviews their unique reactivity & chemoselectivity in ketone, aldehyde & acylsilane synthesis🧪 Applications include natural product synthesis, Vilsmeier–Haack reactions & polymer recycling!
#OpenAccess 👉 buff.ly/34Wm4nT
#OpenAccess 👉 buff.ly/34Wm4nT
William Erb & co-workers show how #hexafluoroisopropanol (HFIP) promotes pseudo-benzylic substitutions, enabling access to bulky diphosphine ligands & phosphonates🧪 Key tools for metal complexes & #phosphine synthesis🌟
#ferrocene
👉 buff.ly/8QjPcGl
#ferrocene
👉 buff.ly/8QjPcGl
October 29, 2025 at 8:02 AM
William Erb & co-workers show how #hexafluoroisopropanol (HFIP) promotes pseudo-benzylic substitutions, enabling access to bulky diphosphine ligands & phosphonates🧪 Key tools for metal complexes & #phosphine synthesis🌟
#ferrocene
👉 buff.ly/8QjPcGl
#ferrocene
👉 buff.ly/8QjPcGl
A fresh look at #gold & #platinum catalysis! ✨ Véronique Michelet @vmichelet06.bsky.social & co-workers review [2+2+2] Prins-type #cyclizations with alkynes/allenes, alkenes & carbonyls🔬 Covers intra/intermolecular strategies & enantioselective applications 🌟
👉 buff.ly/roTiTeW
👉 buff.ly/roTiTeW
October 27, 2025 at 8:02 AM
A fresh look at #gold & #platinum catalysis! ✨ Véronique Michelet @vmichelet06.bsky.social & co-workers review [2+2+2] Prins-type #cyclizations with alkynes/allenes, alkenes & carbonyls🔬 Covers intra/intermolecular strategies & enantioselective applications 🌟
👉 buff.ly/roTiTeW
👉 buff.ly/roTiTeW
Rapid access to 1,2- #diazepines from #pyridines via ylide formation under 370 nm light, as reported in the paper of Tomislav Rovis & coworkers🚀 Tuning the protecting group enables diverse substrates, offering a one-pot route to rare drug-like cores💊
👉 buff.ly/UXBkq9a
👉 buff.ly/UXBkq9a
October 24, 2025 at 7:02 AM
Rapid access to 1,2- #diazepines from #pyridines via ylide formation under 370 nm light, as reported in the paper of Tomislav Rovis & coworkers🚀 Tuning the protecting group enables diverse substrates, offering a one-pot route to rare drug-like cores💊
👉 buff.ly/UXBkq9a
👉 buff.ly/UXBkq9a
⚡Charge-enhanced H-bond & #Brønsted acid catalysis is redefining synthetic chemistry! Boosting rates & selectivity, these systems, like #amidinium & cationic phosphoric acids, bring enzyme-like efficiency, as highlighted in our review by Travis Dudding & co-workers🚀
👉 buff.ly/yidWGLw
👉 buff.ly/yidWGLw
October 22, 2025 at 7:01 AM
⚡Charge-enhanced H-bond & #Brønsted acid catalysis is redefining synthetic chemistry! Boosting rates & selectivity, these systems, like #amidinium & cationic phosphoric acids, bring enzyme-like efficiency, as highlighted in our review by Travis Dudding & co-workers🚀
👉 buff.ly/yidWGLw
👉 buff.ly/yidWGLw
Ni-catalyzed selective monodefluorinative alkylcarbonylation of α-CF₃ styrenes with alkylzinc pivalates under 1 atm CO gas by Jie Li & co-workers🚀 Mild conditions and broad substrate scope make this method highly versatile⚡
#monodefluorination #nickel #catalysis
👉 buff.ly/3EtnXgO
#monodefluorination #nickel #catalysis
👉 buff.ly/3EtnXgO
October 20, 2025 at 7:01 AM
Ni-catalyzed selective monodefluorinative alkylcarbonylation of α-CF₃ styrenes with alkylzinc pivalates under 1 atm CO gas by Jie Li & co-workers🚀 Mild conditions and broad substrate scope make this method highly versatile⚡
#monodefluorination #nickel #catalysis
👉 buff.ly/3EtnXgO
#monodefluorination #nickel #catalysis
👉 buff.ly/3EtnXgO
Exploring #enyne metathesis in green solvents, supercritical fluids & under microwave tech🌱 From cross- to ring-closing pathways, #ruthenium catalysts & tandem strategies, discover it all in this review by Mao, Melot @rmelot.bsky.social & Michelet @vmichelet06.bsky.social 🚀
👉 buff.ly/XNGUsN9
👉 buff.ly/XNGUsN9
October 17, 2025 at 7:02 AM
Exploring #enyne metathesis in green solvents, supercritical fluids & under microwave tech🌱 From cross- to ring-closing pathways, #ruthenium catalysts & tandem strategies, discover it all in this review by Mao, Melot @rmelot.bsky.social & Michelet @vmichelet06.bsky.social 🚀
👉 buff.ly/XNGUsN9
👉 buff.ly/XNGUsN9
Harnessing sunlight for C–C bond formation☀️ Dimethyl-aniline–alkyl halide charge transfer complexes enable reactions with #malonates , #malononitriles & 2-cyano-esters 🔬✨ DFT unveils the mechanism in this study by Alex Szpilman @amszpilman.bsky.social & co-workers
#photochemistry
👉 buff.ly/XNGUsN9
#photochemistry
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October 15, 2025 at 7:01 AM
Harnessing sunlight for C–C bond formation☀️ Dimethyl-aniline–alkyl halide charge transfer complexes enable reactions with #malonates , #malononitriles & 2-cyano-esters 🔬✨ DFT unveils the mechanism in this study by Alex Szpilman @amszpilman.bsky.social & co-workers
#photochemistry
👉 buff.ly/XNGUsN9
#photochemistry
👉 buff.ly/XNGUsN9
Join Thieme #Cheminar “Boron in Organic Synthesis”🔬 with our speakers Profs. Varinder Aggarwal (UK), Andrei Yudin (Canada) & Benjamin Stokes (USA), hosted by Prof. Thierry Ollevier and brought to you by @synopenjournal.bsky.social
📅October 16, 2025 ⏰3 PM (GMT+2)
👉 buff.ly/v41RiQI
📅October 16, 2025 ⏰3 PM (GMT+2)
👉 buff.ly/v41RiQI
October 13, 2025 at 8:02 AM
Join Thieme #Cheminar “Boron in Organic Synthesis”🔬 with our speakers Profs. Varinder Aggarwal (UK), Andrei Yudin (Canada) & Benjamin Stokes (USA), hosted by Prof. Thierry Ollevier and brought to you by @synopenjournal.bsky.social
📅October 16, 2025 ⏰3 PM (GMT+2)
👉 buff.ly/v41RiQI
📅October 16, 2025 ⏰3 PM (GMT+2)
👉 buff.ly/v41RiQI
From Ziegler’s legacy to today’s 🚀 #Organoaluminum chemistry is evolving: hydro-/ #carbometallation, terminal #alumination & C–H activation open new paths! Dive into the review by Piccardi & Micouin @lmicouin.bsky.social ✨
👉 buff.ly/XNGUsN9
👉 buff.ly/XNGUsN9
October 13, 2025 at 7:02 AM
From Ziegler’s legacy to today’s 🚀 #Organoaluminum chemistry is evolving: hydro-/ #carbometallation, terminal #alumination & C–H activation open new paths! Dive into the review by Piccardi & Micouin @lmicouin.bsky.social ✨
👉 buff.ly/XNGUsN9
👉 buff.ly/XNGUsN9
🔬 Check out the 2025 #NobelPrize in Chemistry!
This year’s award goes to Susumu Kitagawa, Richard Robson, and Omar M. Yaghi for their pioneering work on metal–organic frameworks (#MOFs), highly porous materials that can capture CO₂, store gases, and even pull water from the air!
👉 buff.ly/Tj6ROAv
This year’s award goes to Susumu Kitagawa, Richard Robson, and Omar M. Yaghi for their pioneering work on metal–organic frameworks (#MOFs), highly porous materials that can capture CO₂, store gases, and even pull water from the air!
👉 buff.ly/Tj6ROAv
October 10, 2025 at 7:02 PM
🔬 Check out the 2025 #NobelPrize in Chemistry!
This year’s award goes to Susumu Kitagawa, Richard Robson, and Omar M. Yaghi for their pioneering work on metal–organic frameworks (#MOFs), highly porous materials that can capture CO₂, store gases, and even pull water from the air!
👉 buff.ly/Tj6ROAv
This year’s award goes to Susumu Kitagawa, Richard Robson, and Omar M. Yaghi for their pioneering work on metal–organic frameworks (#MOFs), highly porous materials that can capture CO₂, store gases, and even pull water from the air!
👉 buff.ly/Tj6ROAv
Versatile 1,2-oxazin-4-ones pave the way to enantiopure amino #polyols 🧩 Reissig, Zimmer & co-workers show syn/anti selectivity in #Grignard & #enolate additions, δ-lactone & bicyclic polyol formation, plus Pd & SmI₂ reductions⚡
👉 buff.ly/uZan4s9
👉 buff.ly/uZan4s9
October 10, 2025 at 7:01 AM
Versatile 1,2-oxazin-4-ones pave the way to enantiopure amino #polyols 🧩 Reissig, Zimmer & co-workers show syn/anti selectivity in #Grignard & #enolate additions, δ-lactone & bicyclic polyol formation, plus Pd & SmI₂ reductions⚡
👉 buff.ly/uZan4s9
👉 buff.ly/uZan4s9
🚀 Explore cutting-edge strategies for turning propargyl alcohols into #allenes ✨ A short review by Amgoune & co-workers (ICBMS) highlights how transition-metal #photoredox catalysisdrive these advances through oxidative addition & photoinduced C–O cleavage⚡
👉 buff.ly/Sftvtf9
👉 buff.ly/Sftvtf9
October 8, 2025 at 7:02 AM
🚀 Explore cutting-edge strategies for turning propargyl alcohols into #allenes ✨ A short review by Amgoune & co-workers (ICBMS) highlights how transition-metal #photoredox catalysisdrive these advances through oxidative addition & photoinduced C–O cleavage⚡
👉 buff.ly/Sftvtf9
👉 buff.ly/Sftvtf9
☀️Anthore-Dalion @lanthoredalion.bsky.social & co-workers report a Re(I) photocatalyst enabling ultra-fast (<5 min) #deoxygenation of N-heterocyclic & alkyl N-oxides💡Air-tolerant, scalable, and highly functional group-friendly⚡️
#rhenium #photocatalysis
👉 buff.ly/Wj7cEWT
#rhenium #photocatalysis
👉 buff.ly/Wj7cEWT
October 6, 2025 at 7:01 AM
☀️Anthore-Dalion @lanthoredalion.bsky.social & co-workers report a Re(I) photocatalyst enabling ultra-fast (<5 min) #deoxygenation of N-heterocyclic & alkyl N-oxides💡Air-tolerant, scalable, and highly functional group-friendly⚡️
#rhenium #photocatalysis
👉 buff.ly/Wj7cEWT
#rhenium #photocatalysis
👉 buff.ly/Wj7cEWT
🚀Acuña-Bolomey & Oestreich @silicon-martin.bsky.social reveal an enantioconvergent Ni-catalyzed C(sp³)–C(sp³) coupling, unlocking α-chiral #alkylgermanes🧪 Novel PyBox ligands tackle selectivity challenges & pave the way for next-gen #organogermanium chemistry✨
#nickel
👉 buff.ly/5sLCvWB
#nickel
👉 buff.ly/5sLCvWB
October 3, 2025 at 7:01 AM
🚀Acuña-Bolomey & Oestreich @silicon-martin.bsky.social reveal an enantioconvergent Ni-catalyzed C(sp³)–C(sp³) coupling, unlocking α-chiral #alkylgermanes🧪 Novel PyBox ligands tackle selectivity challenges & pave the way for next-gen #organogermanium chemistry✨
#nickel
👉 buff.ly/5sLCvWB
#nickel
👉 buff.ly/5sLCvWB
✨From Special Topic Romanian Chemists in Synthesis✨
One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles
👉 buff.ly/CqvtWHP
One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles
👉 buff.ly/CqvtWHP
October 1, 2025 at 7:02 AM
✨From Special Topic Romanian Chemists in Synthesis✨
One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles
👉 buff.ly/CqvtWHP
One-step breakthrough⚡️A new catalytic system enables efficient synthesis of 5,5′-bi-triazole bis-macrocycles🧪Born from a serendipitous by-product➡️now optimized for selectivity & yield✨
#CuAAC #triazoles #macrocycles
👉 buff.ly/CqvtWHP
✨From Special Topic Romanian Chemists in Synthesis✨
🚀π-Coordination is unlocking new ways for C–H & C–O activation! This review by Mutoh & Ilies highlights Pd–arene–Cr complexes and future transient strategies for sustainable synthesis🧪
#catalysis
👉 buff.ly/hkjGa8v
🚀π-Coordination is unlocking new ways for C–H & C–O activation! This review by Mutoh & Ilies highlights Pd–arene–Cr complexes and future transient strategies for sustainable synthesis🧪
#catalysis
👉 buff.ly/hkjGa8v
September 29, 2025 at 7:02 AM
✨From Special Topic Romanian Chemists in Synthesis✨
🚀π-Coordination is unlocking new ways for C–H & C–O activation! This review by Mutoh & Ilies highlights Pd–arene–Cr complexes and future transient strategies for sustainable synthesis🧪
#catalysis
👉 buff.ly/hkjGa8v
🚀π-Coordination is unlocking new ways for C–H & C–O activation! This review by Mutoh & Ilies highlights Pd–arene–Cr complexes and future transient strategies for sustainable synthesis🧪
#catalysis
👉 buff.ly/hkjGa8v
⚗️First-of-its-kind Co-catalyzed cross-coupling! Gosmini & co-workers report that benzyl sulfonium salts, readily made from alcohols, react with aryl bromides to give a wide variety of #diarylmethanes in good to excellent yields✨
#cobalt #catalysis
👉 buff.ly/kmBppFc
#cobalt #catalysis
👉 buff.ly/kmBppFc
September 26, 2025 at 7:01 AM
⚗️First-of-its-kind Co-catalyzed cross-coupling! Gosmini & co-workers report that benzyl sulfonium salts, readily made from alcohols, react with aryl bromides to give a wide variety of #diarylmethanes in good to excellent yields✨
#cobalt #catalysis
👉 buff.ly/kmBppFc
#cobalt #catalysis
👉 buff.ly/kmBppFc
Why is #fluorine the ultimate game-changer in organic chemistry?💡In their latest review, Zhan-Yong Wang & co-workers cover a decade of #monofluorination breakthroughs – from radical routes to #Selectfluor magic – showing how chemists craft C–F bonds with precision.
👉 buff.ly/nEDKadM
👉 buff.ly/nEDKadM
September 24, 2025 at 7:01 AM
Why is #fluorine the ultimate game-changer in organic chemistry?💡In their latest review, Zhan-Yong Wang & co-workers cover a decade of #monofluorination breakthroughs – from radical routes to #Selectfluor magic – showing how chemists craft C–F bonds with precision.
👉 buff.ly/nEDKadM
👉 buff.ly/nEDKadM
💡Yadav & co-workers developed a divergent DABCO-catalyzed route to allyl #sulfones via α- and γ-substitution of Morita–Baylis–Hillman acetates with #sulfinates, delivering alkyl 2-(phenyl(tosyl)methyl)acrylate derivatives in high yields with excellent stereoselectivity
👉 buff.ly/0UFFoyf
👉 buff.ly/0UFFoyf
September 22, 2025 at 7:01 AM
💡Yadav & co-workers developed a divergent DABCO-catalyzed route to allyl #sulfones via α- and γ-substitution of Morita–Baylis–Hillman acetates with #sulfinates, delivering alkyl 2-(phenyl(tosyl)methyl)acrylate derivatives in high yields with excellent stereoselectivity
👉 buff.ly/0UFFoyf
👉 buff.ly/0UFFoyf