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synopenjournal.bsky.social
SynOpen journal
@synopenjournal.bsky.social
An #OpenAccess Thieme journal. Fast, Fair & Flexible, and committed to providing an excellent publishing experience through the entire process.
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Driving innovation in synthetic chemistry? 🚀 SynOpen is a global platform for the latest research results in #ChemicalSciences. Here’s why that matters for your research:

👁️️ High Readership
📝 Graphical Reviews
👥 Rapid Select Crowd Review
...and more!

Submit today: bit.ly/SynOpenJournal
#OpenAccess
✨ 2025 highlights ✨

🥇 #1 Most Downloaded Paper of 2025

“Sodium Nitrite (NaNO₂): An Impressive and Efficient Nitrating/Nitrosating #Reagent in #OrganicSynthesis
Graphical review by Lamark, Barbosa & Jordão

🔗 Read now: bit.ly/4b9Di3x
#ChemSky #Chemistry #OpenAccess
December 30, 2025 at 2:22 PM
✨ 2025 highlights ✨

📊 Top 5 most downloaded papers of 2025

✅ #2
A convenient #synthesis of CHF₂O-containing #pyrrolidines and related compounds — Perspective building blocks for #DrugDiscovery
by K. Levchenko et al.

🔗 Read here: bit.ly/498FiGQ
#ChemSky #OrganicChemistry
December 29, 2025 at 1:53 PM
✨ 2025 highlights ✨

📊 Top 5 most downloaded papers of 2025

✅ #3
“Synthesis, In Vitro and In Silico Molecular #Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to #Thalidomide as Potent #Antitubercular Agents”
by S. Youssif & team

🔗 Read now: bit.ly/49cOqKG
#ChemSky
December 28, 2025 at 11:53 AM
✨ 2025 highlights ✨

📊 We’re closing the year with the Top 5 most downloaded papers of 2025.

✅ #4
“Recent #Catalytic Applications of #Porphyrin and Phthalocyanine-Based Nanocomposites in #Organic Transformations”
by P. Kumari & co-workers

🔗 Read now: bit.ly/48URmwu
#ChemSky
December 27, 2025 at 12:49 PM
✨️ 2025 highlights ✨️

📊 Our final posts of the year highlight the Top 5 most downloaded papers of 2025.

✅ #5
“Development of a Novel Horner–Wadsworth–Emmons Reagent for the Facile Preparation of Mixed Phosphonoacetates"
by Shigeki Sano & team.

🔗 Read it here: bit.ly/3YcSdT2
#ChemSky #Chemistry
December 26, 2025 at 12:54 PM
✨ 2025 highlights ✨

A year of global connections and great #science for the Syn journals community: 10 events across 8 countries! 🇨🇭 🇰🇷 🇪🇸 🇬🇧 🇨🇳 🇯🇵 🇵🇹 🇮🇹

Thank you to everyone who made these meetings unforgettable! Special thanks to @rohitbhatia10.bsky.social 🇮🇳 for representing us at so many conferences!
December 22, 2025 at 12:22 PM
🎄 2025 highlights! 🎄

The SynOpen Best Paper Award 2024 to Ben Stokes & co-workers (Santa Clara University, 🇺🇸) for their publication "Pd-Catalyzed Transfer Hydrogenation of Alkenes Using Tetrahydroxydiboron as the Sole Hydrogen Donor"

👀 Revisit the paper: bit.ly/3MSJsuR
#Throwback #ChemSky
December 19, 2025 at 9:28 AM
🎄 As 2025 comes to a close, we at @thieme-gruppe.bsky.social look back at our #Cheminar series!

From Chemical Synthesis & #Catalysts to Medicinal #Chemistry, plus special sessions and Best Paper Awardees.
Thanks to all chairs, speakers, and attendees.

👀 More Cheminars in 2026. Stay tuned!
December 16, 2025 at 9:07 AM
📢 Last call for our Thieme #Cheminar!

Dive into the world of Small #Molecules in Medicinal Chemistry.
Session with Profs. Arlene G. Corrêa (🇧🇷) & Kelvin Billingsley (🇺🇸), chaired by Debabrata Maiti (🇮🇳).

📅 Dec 10, 2025 ⏰ 5 PM (CET)

🔗 Register now: bit.ly/4aDJWie
#ChemSky
December 9, 2025 at 11:30 AM
📢 Cheminar Alert!
Our next Thieme #Cheminar is coming up: “Small Molecules in #MedicinalChemistry
📅 Dec 10, 5:00 PM (CET)

Featuring Prof. Arlene Corrêa and Prof. Kelvin Billingsley, with Prof. Debabrata Maiti (EiC of @synlettjournal.bsky.social) chairing.

🔗 Register now: bit.ly/4aDJWie
#ChemSky
December 5, 2025 at 9:15 AM
🧬 New #anticancer candidates from functionalized oxazoles!
M. V. Kachaeva & team report 5-S-substituted 1,3-oxazolylphosphonates and 1,3-oxazole-4-carbonitriles, with several compounds showing high potency against multiple #cancer cell lines!

📄 Read here: bit.ly/4pmeAl4
#ChemSky #MedChem #Synthesis
December 3, 2025 at 9:04 AM
🔬 Prof. Ying Xia and colleagues highlight recent advances in the #synthesis of axially #chiral cycloalkanes, covering key strategies such as asymmetric allylic substitution, #alkene insertion, #carbene cross-coupling, [2+2] #cycloadditions, and #deracemization.

🔗 Read now: bit.ly/4pCRhTy
#ChemSky
November 29, 2025 at 1:21 PM
Potential new type of #herbicides! 🌱
In this paper, J. Frackenpohl & team report the design, #synthesis, and #biological evaluation of substituted azetidinyl carboxamides, developed through scaffold hopping and #bioisosteric strategies.

🔗 Read the full article: bit.ly/4iplJyn
#ChemSky #SAR
November 26, 2025 at 4:50 AM
Prof. Michael P. Doyle & L. De Angelis (UTSA) highlight how 1,2,3-triazine 1-oxides provide a powerful platform for constructing diverse #heterocycles. From nucleophilic substitution & #deoxygenation to Diels–Alder #reactions and more!

🔗 Read the graphical review: bit.ly/48qm7Jg
#ChemSky #Synthesis
November 21, 2025 at 10:32 AM
✨ New Graphical Review!
A. V. Dobrydnev presents overview of synthetic strategies for building endocyclic sulfoximines. They possess unique #physicochemical and structural features, including #chirality and thermal stability.

🔗 Read more: bit.ly/482WRr7
#ChemSky #OrganicChemistry #Heterocycles
November 19, 2025 at 9:02 AM
⚡ In this review, J. Yang & team highlight recent advances in metal-enabled #electrophotocatalysis, integrating photo-, electro-, and metal-catalyzed processes to develop #sustainable routes for C–H activation, #decarboxylation, and cross-coupling under mild conditions.

🔗 Read now: bit.ly/43vqgZH
November 13, 2025 at 9:09 AM
M. V. Kachaeva & team designed and synthesized novel oxazolo[4,5-d]pyrimidine derivatives showing strong activity against glioblastoma and lung #cancer cell lines.

🔍 #MachineLearning, #QSAR modeling, and #docking revealed carbonic anhydrase XII as a potential target.

👉 Read more: bit.ly/47NQt75
November 11, 2025 at 9:01 AM
Reposted by SynOpen journal
🚀 Countdown to SCNOW Virtual Summit, 6–7 Nov! 🌱♻️

Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.

💻 Register NOW: cassyni.com/s/scnow-virt...

#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
October 28, 2025 at 11:21 AM
⚗️ A mild and #metal-free route to 2-hydroxy diarylureas!
This PIFA-mediated ring-opening/coupling of benzoxazoles gives valuable #urea scaffolds with high yields and broad substrate scope.

🔗 Read the full article by M. Yang & team: bit.ly/47rBv81
#ChemSky #OrganicChemistry
November 5, 2025 at 9:00 AM
🌱 From the Virtual Collection: #ClickChemistry and #DrugDiscovery
A simple, metal-free, and eco-friendly approach using chitosan·HCl enables rapid hydrazone #synthesis under mild conditions, delivering high yields and promising #antimycobacterial activity.

🔗 Read here: bit.ly/3WZ09Xl
#ChemSky
November 1, 2025 at 10:44 AM
🧩 From the Virtual Collection: #ClickChemistry and #DrugDiscovery
An efficient click-type formal [2+2] cycloaddition enables the formation of complex #chromophores with remarkable nonlinear optical (NLO) properties.

🔗 Read the full paper: bit.ly/4qpq87O
#ChemSky #OrganicChemistry #OpenAccess
October 23, 2025 at 9:09 AM
⚗️ From Virtual Collection: #ClickChemistry and #DrugDiscovery

N. Jahan & I. Ansary present a review on the synthesis of bioactive macrocycles using ring-closing metathesis, a powerful strategy enabling access to structures with promising #biological activities.

👉 Read here: bit.ly/4hjC3jv
#ChemSky
October 20, 2025 at 9:07 AM
​🚨 LAST CALL! The Thieme #Cheminar starts TODAY.
​Join the session, chaired by our EiC, Prof. Thierry Ollevier.

​Plus: Hear from the SynOpen Most Innovative Paper Award 2024 Winner, Prof. Benjamin Stokes!

⏰️ Starts 3:00 PM (CET).
🔗 Register now: bit.ly/48sqMLq
#ChemSky #Chemistry #Boron
October 16, 2025 at 9:23 AM
Join the next Thieme #Cheminar focusing on the role of boron in #OrganicSynthesis! ​Chaired by our SynOpen Editor-in-Chief, Prof. Thierry Ollevier.

​📅 Oct 16, 3 pm (CEST)

​Don't miss the opportunity to connect with leaders in the field!

​🔗 Secure your spot: bit.ly/48sqMLq
#ChemSky #Chemistry
October 13, 2025 at 8:24 AM
The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi "for the development of metal-organic frameworks."
Congratulations! 🎉

​Full details: www.nobelprize.org/prizes/chemi...
#ChemNobel #ChemSky #Nobel #Science
Nobel Prize in Chemistry 2025
The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks.”
www.nobelprize.org
October 8, 2025 at 10:21 AM