Sussex Blood Cancer Research
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sussexbcr.bsky.social
Sussex Blood Cancer Research
@sussexbcr.bsky.social
A network of research groups across the University of Sussex, Brighton & Sussex Medical School and University Hospitals Sussex NHS trust investigating the causes of blood cancers, and developing new therapeutic strategies to improve patient survival.
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We are now on Bluesky with our new name!

We are a network of research groups across the University of Sussex, Brighton & Sussex Medical School and University Hospitals Sussex NHS trust investigating the causes of blood cancers, and developing new therapeutic strategies to improve patient survival.
Reposted by Sussex Blood Cancer Research
Looking for a PhD on stem cells, microenvironment and gene regulation/alternative splicing. Join us for this great project with @whatchamacaulay.bsky.social
PHD: Are you interested in gene regulation, #immune function, or tech development?

We have a fully-funded 4-year #PhDproject with @whatchamacaulay.bsky.social at the Earlham Institute and @tiagocluis.bsky.social at Imperial looking at niche cell–cell communication.

➡️ buff.ly/M7u6thJ
Exploring niche cell–cell communication through alternative splicing
4-year Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD
buff.ly
October 21, 2025 at 3:29 PM
Reposted by Sussex Blood Cancer Research
Prof. Tim Humphrey and Dr. Rhys Morgan both gave talks at the recent "Science Café" hosted by the Sussex Cancer Fund in partnership with the Macmillan Horizon Centre. A fabulous series of short talks for anyone interested in hearing a little more about the latest developments in cancer research.
Delighted to wave the flag for @gdsc-sussex.bsky.social
@sussexcancer.org
@sussexbcr.bsky.social
sussexcancerfund.co.uk together with Rhys Morgan at the Science Cafe, MacMillan Horizon centre today. Thanks to Rebecca Herbertson and Stephen Robinson for organizing.
@rhysmorganlab.bsky.social
September 30, 2025 at 2:41 PM
🍾New promotion in the network! 🎉

A massive congratulations to Simon Mitchell @mitchell.science from @bsmsmedschool.bsky.social recently promoted to Professor!

Simon has transformed the Cancer Research portfolio at Sussex with his work at the Sussex BCR and the creation of @sussexcancer.org

🙌👊👏
Excited to have been promoted to Professor in Cancer Systems Biology at @bsmsmedschool.bsky.social, University of Sussex, @uniofbrighton.bsky.social
October 11, 2025 at 3:47 PM
Reposted by Sussex Blood Cancer Research
Excited to have been promoted to Professor in Cancer Systems Biology at @bsmsmedschool.bsky.social, University of Sussex, @uniofbrighton.bsky.social
October 9, 2025 at 8:20 PM
Reposted by Sussex Blood Cancer Research
Many cancers begin as precancerous conditions. But what happens when these early cells coexist with a full-blown tumour?

Join us for an MRC funded PhD studentship exploring how primary cancers influence the evolution of precancerous cells.

www.findaphd.com/phds/project...
(MRC DTP) Corrupting the roots: How leukaemia reshapes its ancestors at The University of Manchester on FindAPhD.com
PhD Project - (MRC DTP) Corrupting the roots: How leukaemia reshapes its ancestors at The University of Manchester, listed on FindAPhD.com
www.findaphd.com
October 10, 2025 at 9:16 AM
💰New funding update💰

Congratulations @rhysmorganlab.bsky.social in @biochembiomeduos.bsky.social for obtaining funding from @bloodcanceruk.bsky.social to target abnormal cell signalling mechanisms in AML.

This is now 1 of 6 active Blood Cancer UK grants in our growing network at Sussex. 👊 🔬🧬🥼🩸
Very grateful to have been awarded our first @bloodcanceruk.bsky.social research grant over the summer for our work targeting aberrant Wnt/β-catenin signalling in acute myeloid leukaemia (AML).

Our new project headed by Dr Wagstaff begins Oct 1st developing new ways to target oncogenic β-catenin 👊
October 7, 2025 at 6:53 AM
Reposted by Sussex Blood Cancer Research
Very grateful to have been awarded our first @bloodcanceruk.bsky.social research grant over the summer for our work targeting aberrant Wnt/β-catenin signalling in acute myeloid leukaemia (AML).

Our new project headed by Dr Wagstaff begins Oct 1st developing new ways to target oncogenic β-catenin 👊
September 30, 2025 at 3:06 PM
Reposted by Sussex Blood Cancer Research
Delighted to wave the flag for @gdsc-sussex.bsky.social
@sussexcancer.org
@sussexbcr.bsky.social
sussexcancerfund.co.uk together with Rhys Morgan at the Science Cafe, MacMillan Horizon centre today. Thanks to Rebecca Herbertson and Stephen Robinson for organizing.
@rhysmorganlab.bsky.social
September 29, 2025 at 8:26 PM
Our Co-Directors Prof @chrispepper68.bsky.social and Dr @rhysmorganlab.bsky.social explain the mission and vision for the Sussex Blood Cancer Research network.

@sussexcancer.org @bsmsmedschool.bsky.social @biochembiomeduos.bsky.social
💡 How are #BSMS researchers working to change the future of blood cancer?
Prof Chris Pepper and Dr Rhys Morgan share their journey, their goals and why this research matters.
▶Watch here: www.youtube.com/watch?v=0EwD...
@sussexbcr.bsky.social #MedicalResearch
Prof Chris Pepper and Dr Rhys Morgan - Sussex Blood Cancer Research
YouTube video by Brighton and Sussex Medical School
www.youtube.com
September 23, 2025 at 4:17 PM
Reposted by Sussex Blood Cancer Research
💡 How are #BSMS researchers working to change the future of blood cancer?
Prof Chris Pepper and Dr Rhys Morgan share their journey, their goals and why this research matters.
▶Watch here: www.youtube.com/watch?v=0EwD...
@sussexbcr.bsky.social #MedicalResearch
Prof Chris Pepper and Dr Rhys Morgan - Sussex Blood Cancer Research
YouTube video by Brighton and Sussex Medical School
www.youtube.com
September 23, 2025 at 7:33 AM
🗞️ New network publication!🗞️

Final year PhD student Aimilia Vareli in @bsmsmedschool.bsky.social of @mitchell.science lab publishes her doctoral studies in @springernature.com
#CellDeathDisease showing inhibition of NFkB signalling increases BH3 mimetic sensitivity in the lymphoma microenvironment.
September 9, 2025 at 10:11 AM
Reposted by Sussex Blood Cancer Research
New paper led by Aimilia Vareli out now.
nature.com/articles/s41...
The lymphoma microenvironment stops BH3-mimetics working.
In vitro/vivo/silico, we find inhibition of NFκB makes BH3-mimetics great again.🧵
@sussexbcr.bsky.social @bsmsmedschool.bsky.social @leukaemiauk.bsky.social @sussexcancer.org
Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL - Cell Death & Disease
Cell Death & Disease - Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL
nature.com
August 18, 2025 at 11:05 AM
Join Dr Jasmeen Oberoi's research group on a @bloodcanceruk.bsky.social funded project as a Research Technician in Protein Biochemistry for 6mo, investigating structure and function of fusion kinase complexes in leukaemia.

Great opportunity for a candidate looking to build research experience!
🧬🧪 A research technician position - Protein Biochemistry (6 months) is available in my lab @gdsc-sussex.bsky.social investigating structure and function of fusion kinase complexes in Leukaemia.

📅 Deadline: 29th September 2025.

🙏 Please share with anyone who might be interested.
Research Technician – Protein Biochemistry at University of Sussex
Explore an exciting academic career as a Research Technician – Protein Biochemistry. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
September 9, 2025 at 10:08 AM
Reposted by Sussex Blood Cancer Research
🧬🧪 A research technician position - Protein Biochemistry (6 months) is available in my lab @gdsc-sussex.bsky.social investigating structure and function of fusion kinase complexes in Leukaemia.

📅 Deadline: 29th September 2025.

🙏 Please share with anyone who might be interested.
Research Technician – Protein Biochemistry at University of Sussex
Explore an exciting academic career as a Research Technician – Protein Biochemistry. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
September 9, 2025 at 8:35 AM
Reposted by Sussex Blood Cancer Research
Research is never a solo effort.
It takes teamwork. It takes belief. It takes collaboration across disciplines, institutions, and communities.
We know what it takes to beat blood cancer.
#BloodCancerAwarenessMonth
@bloodcanceruk.bsky.social @sussexbcr.bsky.social @sussexcancer.org 🩸
September 4, 2025 at 2:18 PM
🗞️ New network publication! 📰

Final year PhD student Aimilia Vareli in @bsmsmedschool.bsky.social in the @mitchell.science lab publishes her doctoral studies in @springernature.com #CellDeathDisease showing inhibition of NFkB signalling increases sensitivity to BH3 mimetics for lymphoma treatment.
August 28, 2025 at 5:43 PM
Reposted by Sussex Blood Cancer Research
Great post-doctoral opportunity in the laboratory of Dr Jasmeen Oberoi — who has just joined us as a team leader in the GDSC.
📢 New Postdoc opportunity

🧬🧪🩸 Excited to share an MRC funded Research Fellow position is available in my lab @gdsc-sussex.bsky.social to investigate novel approaches to disrupt the function of fusion kinases and their regulation by the HSP90 molecular chaperone system in leukaemia.
Research Fellow in Cancer Research at University of Sussex
An academic position as a Research Fellow in Cancer Research is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.
www.jobs.ac.uk
July 18, 2025 at 2:01 PM
Reposted by Sussex Blood Cancer Research
📢 New Postdoc opportunity

🧬🧪🩸 Excited to share an MRC funded Research Fellow position is available in my lab @gdsc-sussex.bsky.social to investigate novel approaches to disrupt the function of fusion kinases and their regulation by the HSP90 molecular chaperone system in leukaemia.
Research Fellow in Cancer Research at University of Sussex
An academic position as a Research Fellow in Cancer Research is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.
www.jobs.ac.uk
July 17, 2025 at 5:11 PM
Completed your PhD? Interested in leukaemia research? Want to join a new/exciting PI as they establish their group at @gdsc-sussex.bsky.social

Then this post doc with new MRC CDA Fellow & @bloodcanceruk.bsky.social funded Dr @jasmeenoberoi.bsky.social is 4 you 👇

jobs.sussex.ac.uk/job/fe31a03c...
Research Fellow in Cancer Research Ref: 41067 (Fixed Term) - Job page - University of Sussex Job Search
jobs.sussex.ac.uk
July 17, 2025 at 2:23 PM
🗞️ New publication from the network 🗞️

Dr @ejayawant.bsky.social now working at the Pepper group in @bsmsmedschool.bsky.social review the state of play in computational modelling of B-cell lymphomas, led by @mitchell.science and now out at @biochemsoc.bsky.social Transactions.
New paper led by @ejayawant.bsky.social 🎉
We review:
- how computational biology is helping us understand lymphoma,
- how machine learning and cell simulations make sense of vast amounts of data,
- how models can personalise treatments to each person with lymphoma.
portlandpress.com/biochemsoctr...
July 7, 2025 at 2:53 PM
Reposted by Sussex Blood Cancer Research
New paper led by @ejayawant.bsky.social 🎉
We review:
- how computational biology is helping us understand lymphoma,
- how machine learning and cell simulations make sense of vast amounts of data,
- how models can personalise treatments to each person with lymphoma.
portlandpress.com/biochemsoctr...
July 4, 2025 at 4:02 PM
Reposted by Sussex Blood Cancer Research
Artist’s blood cancer treatment inspires powerful new exhibition at University of Brighton, @bsmsmedschool.bsky.social

www.brighton.ac.uk/news/2025/ar...
Artist’s blood cancer treatment inspires powerful new exhibition at University of Brighton
A University of Brighton graduate has turned his own cancer journey into a striking art installation exploring illness and the duality of medical treatment.
www.brighton.ac.uk
June 10, 2025 at 9:39 PM
Reposted by Sussex Blood Cancer Research
Prof. Evi Soutoglou describing what happens when DNA breaks, and when to cut, and when not to — on Brighton seafront, as part of Soapbox Science 2025 — a public outreach platform that promote women and non-binary scientists and the science that they carry out. ‪@soapboxscience.bsky.social‬
June 23, 2025 at 10:38 AM
Reposted by Sussex Blood Cancer Research
Dr. Luke Yates, along with Prof. Zhang and Prof. Burgers, summarise our current mechanistic understanding of the DNA damage checkpoint; inc. structural studies of ATM and ATR and how these work together to prevent cancer.
doi.org/10.1146/annu...
@layates.bsky.social @crick.ac.uk @washu.bsky.social
DNA Damage and Replication Stress Checkpoints | Annual Reviews
DNA damage checkpoints are key regulatory signaling cascades that arrest cell cycle progression upon DNA damage or upon DNA replication stalling and allow time for repair or correction. Failure to eli...
doi.org
June 24, 2025 at 8:41 AM
Reposted by Sussex Blood Cancer Research
Following on from our recent paper showing novel post-transcriptional roles for B-catenin in leukaemia cells, a very well done to Drs Sevim & Park for writing a superb review in @natureportfolio.nature.com Oncogene summarising our current understanding of this field.

www.nature.com/articles/s41...
Post-transcriptional control of gene expression by β-catenin: expanding the non-canonical ARMoury - Oncogene
Oncogene - Post-transcriptional control of gene expression by β-catenin: expanding the non-canonical ARMoury
www.nature.com
June 25, 2025 at 11:21 AM