Sam Stephens IA
@stephenslab.bsky.social
Scientist, beta-cell biologist at U Iowa FOE Diabetes Center
https://stephens.lab.uiowa.edu/
https://stephens.lab.uiowa.edu/
Excited to share a new study from the lab published in Diabetes. This was amazing work performed by Sandra Blom!
"Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition"
doi.org/10.2337/db25...
"Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition"
doi.org/10.2337/db25...
Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition
Type 1 diabetes (T1D) is caused by the selective autoimmune ablation of pancreatic β-cells. Emerging evidence reveals β-cell secretory dysfunction arises e
doi.org
September 5, 2025 at 3:48 PM
Excited to share a new study from the lab published in Diabetes. This was amazing work performed by Sandra Blom!
"Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition"
doi.org/10.2337/db25...
"Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition"
doi.org/10.2337/db25...
Thanks to Matt Merrins for helping us upgrade our microscope for perifusion studies @merrinslab.bsky.social
April 19, 2025 at 8:59 PM
Thanks to Matt Merrins for helping us upgrade our microscope for perifusion studies @merrinslab.bsky.social
Check out our recent review describing the bidirectional regulation between the ER and mitochondria
www.mdpi.com/3216548
www.mdpi.com/3216548
April 3, 2025 at 3:02 AM
Check out our recent review describing the bidirectional regulation between the ER and mitochondria
www.mdpi.com/3216548
www.mdpi.com/3216548