@stefarber.bsky.social
Yes, it is crazy that all these papers came out at around the same time! McKenna Feltes in my lab together with my JHU colleagues Alexey Zimin and Steven Salzberg developed this amazing platform called WheresWalker to make positional cloning much easier.
journals.plos.org/plosgenetics...
journals.plos.org/plosgenetics...
Phenotype to genotype: A new and rapid approach using whole-genome sequencing
Author summary Forward genetic mutagenesis screening is an unbiased approach for the identification of mutations linked to a phenotype of interest. While this approach can be a powerful tool for uncov...
journals.plos.org
July 15, 2025 at 8:25 PM
Yes, it is crazy that all these papers came out at around the same time! McKenna Feltes in my lab together with my JHU colleagues Alexey Zimin and Steven Salzberg developed this amazing platform called WheresWalker to make positional cloning much easier.
journals.plos.org/plosgenetics...
journals.plos.org/plosgenetics...
A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. This was quite a journey for Dan and I and it is great to get it out there for other folks to appreciate - awesome job Dan
doi.org/10.7554/eLif...
doi.org/10.7554/eLif...
doi.org
July 14, 2025 at 3:54 PM
A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. This was quite a journey for Dan and I and it is great to get it out there for other folks to appreciate - awesome job Dan
doi.org/10.7554/eLif...
doi.org/10.7554/eLif...
Today Josh Derrick's paper came out -- A deep dive to create a state-of-the-art method of modeling and quantifying o HPLC Chromatograms - it is both computational and contains "wet lab" experiments. doi.org/10.1016/j.jc...
Redirecting
doi.org
July 13, 2025 at 6:44 PM
Today Josh Derrick's paper came out -- A deep dive to create a state-of-the-art method of modeling and quantifying o HPLC Chromatograms - it is both computational and contains "wet lab" experiments. doi.org/10.1016/j.jc...
Creb3l3 loss = lipid overload in the gut 🥴
We show that Creb3l3 deficiency leads to intestinal lipid accumulation + altered ApoB lipoprotein metabolism.
Big implications for lipid disorders + metabolic disease!
🔗 www.jlr.org/article/S002...
#lipidmetabolism #zebrafish #CREB3L3 #metabolism
We show that Creb3l3 deficiency leads to intestinal lipid accumulation + altered ApoB lipoprotein metabolism.
Big implications for lipid disorders + metabolic disease!
🔗 www.jlr.org/article/S002...
#lipidmetabolism #zebrafish #CREB3L3 #metabolism
Creb3l3 deficiency promotes intestinal lipid accumulation and alters ApoB-containing lipoprotein kinetics
Elevated levels of triglycerides in the bloodstream, a condition known as hypertriglyceridemia,
represent a significant risk factor for the development of metabolic disorders and
cardiovascular diseas...
www.jlr.org
July 13, 2025 at 6:38 PM
Creb3l3 loss = lipid overload in the gut 🥴
We show that Creb3l3 deficiency leads to intestinal lipid accumulation + altered ApoB lipoprotein metabolism.
Big implications for lipid disorders + metabolic disease!
🔗 www.jlr.org/article/S002...
#lipidmetabolism #zebrafish #CREB3L3 #metabolism
We show that Creb3l3 deficiency leads to intestinal lipid accumulation + altered ApoB lipoprotein metabolism.
Big implications for lipid disorders + metabolic disease!
🔗 www.jlr.org/article/S002...
#lipidmetabolism #zebrafish #CREB3L3 #metabolism
So proud of my lab's output in both papers and presentations at international meetings!
July 13, 2025 at 6:37 PM
So proud of my lab's output in both papers and presentations at international meetings!
Reposted
"Questioning is the way of learning,"
Encourage your children to ask questions, not to accept existing answers.
Encourage your children to ask questions, not to accept existing answers.
July 13, 2025 at 2:20 PM
"Questioning is the way of learning,"
Encourage your children to ask questions, not to accept existing answers.
Encourage your children to ask questions, not to accept existing answers.
Reposted
Carl Sagan is one of my heroes right up there with Theodor Seuss Geisel (Dr. Seuss). Sagan's comments are so true now - the consummate scientific communicator.
July 13, 2025 at 6:20 PM
Carl Sagan is one of my heroes right up there with Theodor Seuss Geisel (Dr. Seuss). Sagan's comments are so true now - the consummate scientific communicator.
I will be there and welcome other Baltimoreans to join me
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 20, 2025 at 3:13 AM
I will be there and welcome other Baltimoreans to join me
Reposted
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence