Stefan Schattgen
@sschattgen.bsky.social
Immunologist at St Jude Children’s Research Hospital | TCRs | Systems Immunology | Dad
Reposted by Stefan Schattgen
How much of the TCR repertoire can we make sense of? Can your TCR and GEX data be put in the context of other conditions/tissues? How many varieties of T cells are in the repertoire zoo? All these questions (& more) addressed in our latest preprint: MetaCoNGA www.biorxiv.org/content/10.1... . a 🧵
Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes
Single-cell techniques allow concurrent study of gene activity and T cell receptor (TCR) sequences, identifying connections between TCR structure and cell traits. Expanding on our CoNGA software, we p...
www.biorxiv.org
July 14, 2025 at 11:52 PM
How much of the TCR repertoire can we make sense of? Can your TCR and GEX data be put in the context of other conditions/tissues? How many varieties of T cells are in the repertoire zoo? All these questions (& more) addressed in our latest preprint: MetaCoNGA www.biorxiv.org/content/10.1... . a 🧵
We're still accepting submissions for the 'T cell responses to influenza' collection, which I'm guest editing with BMC Immunology. Please feel free to reach out if you're interested and would like to learn more.
July 14, 2025 at 2:39 PM
We're still accepting submissions for the 'T cell responses to influenza' collection, which I'm guest editing with BMC Immunology. Please feel free to reach out if you're interested and would like to learn more.
Reposted by Stefan Schattgen
Retroelement-specific tissue resident T cells control tissue resilience and predisposition to inflammation
papers.ssrn.com/sol3/papers....
@belkaidlab.bsky.social
papers.ssrn.com/sol3/papers....
@belkaidlab.bsky.social
April 7, 2025 at 11:57 PM
Retroelement-specific tissue resident T cells control tissue resilience and predisposition to inflammation
papers.ssrn.com/sol3/papers....
@belkaidlab.bsky.social
papers.ssrn.com/sol3/papers....
@belkaidlab.bsky.social
Excited to announce a call for submissions for a special collection on T cell responses to influenza that I'm guest editing! If you're doing research in this area, I encourage you to submit your work. Feel free to reach out for information. #BMCimmunology #Tcells
📢 #BMCImmunology Call for papers - T cell responses to influenza 📢
Submission Deadline: 28 October 2025
Guest Editor: @sschattgen.bsky.social
www.biomedcentral.com/collections/...
Submission Deadline: 28 October 2025
Guest Editor: @sschattgen.bsky.social
www.biomedcentral.com/collections/...
Call for papers - T cell responses to influenza
www.biomedcentral.com
February 26, 2025 at 6:06 PM
Excited to announce a call for submissions for a special collection on T cell responses to influenza that I'm guest editing! If you're doing research in this area, I encourage you to submit your work. Feel free to reach out for information. #BMCimmunology #Tcells
Reposted by Stefan Schattgen
Our paper is out!
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity
LCK-mutant mice help define the role of LCK–co-receptor association in T cell development and immune responses.
www.science.org
February 21, 2025 at 10:32 PM
Our paper is out!
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...
Reposted by Stefan Schattgen
Dynamic trajectories of human peripheral immune cells from birth to old age
@natimmunol.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@natimmunol.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integrating single-cell RNA and T cell/B cell receptor sequencing with mass cytometry reveals dynamic trajectories of human peripheral immune cells from birth to old age - Nature Immunology
In this Resource, authors profile peripheral immune cells from a total of 220 healthy volunteers from birth to over 90 years. This revealed that T cells were most affected by aging with divergent agin...
www.nature.com
January 29, 2025 at 9:23 PM
Dynamic trajectories of human peripheral immune cells from birth to old age
@natimmunol.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@natimmunol.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Stefan Schattgen
TLS_Finder: An algorithm for Identifying Tertiary Lymphoid Structures Using Immune Cell Spatial Coordinates www.biorxiv.org/content/10....
December 31, 2024 at 3:15 PM
TLS_Finder: An algorithm for Identifying Tertiary Lymphoid Structures Using Immune Cell Spatial Coordinates www.biorxiv.org/content/10....
Great day of talks and insights on the NIH Influenza Immunity imprinting meeting
December 11, 2024 at 12:42 AM
Great day of talks and insights on the NIH Influenza Immunity imprinting meeting
Reposted by Stefan Schattgen
Inspired by @rodrahimi.bsky.social 's noble efforts linking immunologists together over here, let's try and get more specifically TCR/BCR/AIRR/repertoire chat going with this starter park
go.bsky.app/Gi2dcGd
Drop me a beep to get added or suggest others!
go.bsky.app/Gi2dcGd
Drop me a beep to get added or suggest others!
November 18, 2024 at 5:21 AM
Inspired by @rodrahimi.bsky.social 's noble efforts linking immunologists together over here, let's try and get more specifically TCR/BCR/AIRR/repertoire chat going with this starter park
go.bsky.app/Gi2dcGd
Drop me a beep to get added or suggest others!
go.bsky.app/Gi2dcGd
Drop me a beep to get added or suggest others!