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sroman.bsky.social
Sharon Roman (n of 1)
@sroman.bsky.social
83 followers 82 following 100 posts
Using words for better healthcare: MSARD, JNNP, BMJ & MSJ. JNNP Patient Editorial Board, BC Brain Wellness Chair, CMAJ Patient Advisory Panel. MS research explained ↘️ https://tremlettsmsresearchexplained.wordpress.com/
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Sharon Roman (n of 1) @sroman.bsky.social · Jun 7
About us tremlettsmsresearchexplained.wordpress.com We believe that research findings should be explained simply, empowering those who stand to benefit from it with knowledge to help guide decisions in care.

Subscribe (free) for real-time #MS research ⬇️

tremlettsmsresearchexplained.wordpress.com
Tremlett's MS Research Explained
Prof. Tremlett's multiple sclerosis (MS) research in plain language
tremlettsmsresearchexplained.wordpress.com
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
Having a psychiatric condition after an #MS diagnosis is associated with greater disability over time.

📣 New study investigated whether psychiatric conditions (e.g. depression, anxiety) before MS onset affects future disability.

It’s ⬇️ tremlettsmsresearchexplained.wordpress.com/2025/10/27/p...
Psychiatric Morbidity During the Multiple Sclerosis Prodrome is Associated with Future Disability Explained
by Sharon Roman[i] Mounting evidence supports an early phase of multiple sclerosis (MS) known as a prodrome. A prodromal phase is an early phase of nonspecific signs and symptoms that occur before …
tremlettsmsresearchexplained.wordpress.com
October 27, 2025 at 11:40 PM
sroman.bsky.social
Having a psychiatric condition after an #MS diagnosis is associated with greater disability over time.

📣 New study investigated whether psychiatric conditions (e.g. depression, anxiety) before MS onset affects future disability.

It’s ⬇️ tremlettsmsresearchexplained.wordpress.com/2025/10/27/p...
Psychiatric Morbidity During the Multiple Sclerosis Prodrome is Associated with Future Disability Explained
by Sharon Roman[i] Mounting evidence supports an early phase of multiple sclerosis (MS) known as a prodrome. A prodromal phase is an early phase of nonspecific signs and symptoms that occur before …
tremlettsmsresearchexplained.wordpress.com
October 27, 2025 at 11:40 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
What are the long-term health effects of interferon-beta use in people with #MS?

💥New population-based drug safety study with up to >20 years of follow-up published.

It’s explained: tremlettsmsresearchexplained.wordpress.com/2025/10/15/r...
Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy explained
by Sharon Roman[i] Interferon-b (Beta) is involved in the body’s response to infection and acts as a crucial part of the immune system. Research has previously suggested that too much interferon-be…
tremlettsmsresearchexplained.wordpress.com
October 21, 2025 at 7:23 PM
sroman.bsky.social
What are the long-term health effects of interferon-beta use in people with #MS?

💥New population-based drug safety study with up to >20 years of follow-up published.

It’s explained: tremlettsmsresearchexplained.wordpress.com/2025/10/15/r...
Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy explained
by Sharon Roman[i] Interferon-b (Beta) is involved in the body’s response to infection and acts as a crucial part of the immune system. Research has previously suggested that too much interferon-be…
tremlettsmsresearchexplained.wordpress.com
October 21, 2025 at 7:23 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
Should people radiologically isolated syndrome (RIS) be treated with an #MS therapy?

📣 New study found treatment associated with ⬇️ or delayed risk of developing MS, but with ⬆️ adverse effects.

It’s explained tremlettsmsresearchexplained.wordpress.com/2025/10/16/d...
Disease modifying treatment of radiologically isolated syndrome: a systematic review of the use, efficacy, effectiveness, and safety explained
by Sharon Roman[i] Radiologically isolated syndrome (RIS), first formally defined in 2009, is a distinct condition in the range of central nervous system demyelinating diseases such as multiple scl…
tremlettsmsresearchexplained.wordpress.com
October 16, 2025 at 3:52 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
💥Study of 19k people (>20 years) with #MS taking interferon-beta and risk of cardiovascular & autoimmune disease found a small ⬆️ risk of cardiovascular disease with longer interferon-beta use.

The benefits are still clear.

It’s explained tremlettsmsresearchexplained.wordpress.com/2025/10/15/r...
Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy explained
by Sharon Roman[i] Interferon-b (Beta) is involved in the body’s response to infection and acts as a crucial part of the immune system. Research has previously suggested that too much interferon-be…
tremlettsmsresearchexplained.wordpress.com
October 15, 2025 at 5:56 PM
sroman.bsky.social
Should people radiologically isolated syndrome (RIS) be treated with an #MS therapy?

📣 New study found treatment associated with ⬇️ or delayed risk of developing MS, but with ⬆️ adverse effects.

It’s explained tremlettsmsresearchexplained.wordpress.com/2025/10/16/d...
Disease modifying treatment of radiologically isolated syndrome: a systematic review of the use, efficacy, effectiveness, and safety explained
by Sharon Roman[i] Radiologically isolated syndrome (RIS), first formally defined in 2009, is a distinct condition in the range of central nervous system demyelinating diseases such as multiple scl…
tremlettsmsresearchexplained.wordpress.com
October 16, 2025 at 3:52 PM
sroman.bsky.social
💥Study of 19k people (>20 years) with #MS taking interferon-beta and risk of cardiovascular & autoimmune disease found a small ⬆️ risk of cardiovascular disease with longer interferon-beta use.

The benefits are still clear.

It’s explained tremlettsmsresearchexplained.wordpress.com/2025/10/15/r...
Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy explained
by Sharon Roman[i] Interferon-b (Beta) is involved in the body’s response to infection and acts as a crucial part of the immune system. Research has previously suggested that too much interferon-be…
tremlettsmsresearchexplained.wordpress.com
October 15, 2025 at 5:56 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
The ED is often used for kids with severe/unexplained symptoms. Neurologic emergencies make up 1/3 of severe ED cases in kids.

Patterns (rates & reasons) of ED use may reveal potential early warning signs before paediatric-onset #MS.

⬇️
tremlettsmsresearchexplained.wordpress.com/2025/09/17/u...
Use of the Emergency Department Before Pediatric-Onset Multiple Sclerosis Explained
by Sharon Roman[i] Paediatric-onset MS (PoMS), defined as MS onset under aged 18, makes up approximately 3–10% of all MS cases. PoMS is associated with higher relapse rates, and higher lesion load …
tremlettsmsresearchexplained.wordpress.com
September 30, 2025 at 4:06 PM
sroman.bsky.social
The ED is often used for kids with severe/unexplained symptoms. Neurologic emergencies make up 1/3 of severe ED cases in kids.

Patterns (rates & reasons) of ED use may reveal potential early warning signs before paediatric-onset #MS.

⬇️
tremlettsmsresearchexplained.wordpress.com/2025/09/17/u...
Use of the Emergency Department Before Pediatric-Onset Multiple Sclerosis Explained
by Sharon Roman[i] Paediatric-onset MS (PoMS), defined as MS onset under aged 18, makes up approximately 3–10% of all MS cases. PoMS is associated with higher relapse rates, and higher lesion load …
tremlettsmsresearchexplained.wordpress.com
September 30, 2025 at 4:06 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
New study examined emergency dept. use by rates & reasons in the years before paediatric-onset #MS.

Higher rates of ED visits began 12 years before & rose for 7 reasons. One year before onset, rates significantly ⬆️ for 5 reasons.

It’s ⬇️
tremlettsmsresearchexplained.wordpress.com/2025/09/17/u...
Use of the Emergency Department Before Pediatric-Onset Multiple Sclerosis Explained
by Sharon Roman[i] Paediatric-onset MS (PoMS), defined as MS onset under aged 18, makes up approximately 3–10% of all MS cases. PoMS is associated with higher relapse rates, and higher lesion load …
tremlettsmsresearchexplained.wordpress.com
September 17, 2025 at 4:44 PM
sroman.bsky.social
New study examined emergency dept. use by rates & reasons in the years before paediatric-onset #MS.

Higher rates of ED visits began 12 years before & rose for 7 reasons. One year before onset, rates significantly ⬆️ for 5 reasons.

It’s ⬇️
tremlettsmsresearchexplained.wordpress.com/2025/09/17/u...
Use of the Emergency Department Before Pediatric-Onset Multiple Sclerosis Explained
by Sharon Roman[i] Paediatric-onset MS (PoMS), defined as MS onset under aged 18, makes up approximately 3–10% of all MS cases. PoMS is associated with higher relapse rates, and higher lesion load …
tremlettsmsresearchexplained.wordpress.com
September 17, 2025 at 4:44 PM
sroman.bsky.social
Okay, all. What if I told you #MS begins far earlier than previously thought? ⬇️
sroman.bsky.social Sharon Roman (n of 1) @sroman.bsky.social · Aug 8
#MS may begin far earlier than previously thought.
sroman.bsky.social Sharon Roman (n of 1) @sroman.bsky.social · Aug 5
💥 study examining healthcare use 25 years before neurologist-determined #MS symptom onset adds new insight to the early phase (prodrome) of MS.

Signs emerge 15 years before diagnosis challenging assumptions of when MS begins.

Explained⬇️

tremlettsmsresearchexplained.wordpress.com/2025/08/05/h...
September 12, 2025 at 3:30 AM
sroman.bsky.social
#ICYMI children with #MS face additional barriers to treatment.
September 11, 2025 at 9:08 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
#MS is the same disease in children & adults. Studies show effectiveness of MS therapies in long-term outcomes, but approved therapies for children are scarce.

What are the barriers to treatment for children with MS?

It's explained⬇️
tremlettsmsresearchexplained.wordpress.com/2025/08/27/a...
Access to therapy for children and adolescents with multiple sclerosis: global considerations in preventing disease progression explained
by Sharon Roman[i] Paediatric-onset multiple sclerosis (PoMS), defined as MS onset under aged 18, makes up approximately 1–5% of all MS cases. Globally, an estimated 30,000 children have MS. PoMS i…
tremlettsmsresearchexplained.wordpress.com
August 27, 2025 at 5:11 PM
sroman.bsky.social
#MS is the same disease in children & adults. Studies show effectiveness of MS therapies in long-term outcomes, but approved therapies for children are scarce.

What are the barriers to treatment for children with MS?

It's explained⬇️
tremlettsmsresearchexplained.wordpress.com/2025/08/27/a...
Access to therapy for children and adolescents with multiple sclerosis: global considerations in preventing disease progression explained
by Sharon Roman[i] Paediatric-onset multiple sclerosis (PoMS), defined as MS onset under aged 18, makes up approximately 1–5% of all MS cases. Globally, an estimated 30,000 children have MS. PoMS i…
tremlettsmsresearchexplained.wordpress.com
August 27, 2025 at 5:11 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
#MS may begin far earlier than previously thought.
August 8, 2025 at 7:03 PM
sroman.bsky.social
#MS may begin far earlier than previously thought.
August 8, 2025 at 7:03 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
💥 study examining healthcare use 25 years before neurologist-determined #MS symptom onset adds new insight to the early phase (prodrome) of MS.

Signs emerge 15 years before diagnosis challenging assumptions of when MS begins.

Explained⬇️

tremlettsmsresearchexplained.wordpress.com/2025/08/05/h...
Healthcare use before multiple sclerosis symptom onset explained
by Sharon Roman[i] Several chronic neurologic disorders have a recognized early phase of disease known as a prodromal phase, enabling early detection and intervention. A prodromal phase is an early…
tremlettsmsresearchexplained.wordpress.com
August 5, 2025 at 4:38 PM
sroman.bsky.social
💥 study examining healthcare use 25 years before neurologist-determined #MS symptom onset adds new insight to the early phase (prodrome) of MS.

Signs emerge 15 years before diagnosis challenging assumptions of when MS begins.

Explained⬇️

tremlettsmsresearchexplained.wordpress.com/2025/08/05/h...
Healthcare use before multiple sclerosis symptom onset explained
by Sharon Roman[i] Several chronic neurologic disorders have a recognized early phase of disease known as a prodromal phase, enabling early detection and intervention. A prodromal phase is an early…
tremlettsmsresearchexplained.wordpress.com
August 5, 2025 at 4:38 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
Happy third anniversary 🎉 to …ettsmsresearchexplained.wordpress.com!

Three years of explaining real-time #MS research in plain language. We believe research findings should be explained simply, empowering those who stand to benefit with knowledge to help guide decisions in care.

Join us!
July 24, 2025 at 9:31 PM
sroman.bsky.social
Happy third anniversary 🎉 to …ettsmsresearchexplained.wordpress.com!

Three years of explaining real-time #MS research in plain language. We believe research findings should be explained simply, empowering those who stand to benefit with knowledge to help guide decisions in care.

Join us!
July 24, 2025 at 9:31 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
We're dedicated to making #MS research easier to understand. We believe research findings should be explained simply, empowering those who stand to benefit from it with knowledge to help guide decisions in care.

tremlettsmsresearchexplained.wordpress.com

✔️real-time study results in plain language
Tremlett's MS Research Explained
Prof. Tremlett's multiple sclerosis (MS) research in plain language
tremlettsmsresearchexplained.wordpress.com
March 1, 2025 at 11:31 PM
Reposted by Sharon Roman (n of 1)
sroman.bsky.social
Chronic conditions may start years before classical symptoms occur. Often, signs & symptoms not specific to the disease occur in this early phase (prodrome).

💥Study describes healthcare use 2-3 decades before #MS onset.

It’s explained ⬇️

tremlettsmsresearchexplained.wordpress.com/2025/06/26/p...
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event Explained
by Sharon Roman[i] Chronic conditions may start years before classical symptoms appear. Often, signs and symptoms not specific to the condition occur before classical symptoms in what is known as a…
tremlettsmsresearchexplained.wordpress.com
July 3, 2025 at 4:27 PM
sroman.bsky.social
Chronic conditions may start years before classical symptoms occur. Often, signs & symptoms not specific to the disease occur in this early phase (prodrome).

💥Study describes healthcare use 2-3 decades before #MS onset.

It’s explained ⬇️

tremlettsmsresearchexplained.wordpress.com/2025/06/26/p...
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event Explained
by Sharon Roman[i] Chronic conditions may start years before classical symptoms appear. Often, signs and symptoms not specific to the condition occur before classical symptoms in what is known as a…
tremlettsmsresearchexplained.wordpress.com
July 3, 2025 at 4:27 PM