Saba Parvez
@sparvez.bsky.social
Asst. Professor @Northwestern University CDB, large scale functional genetics in 🦓 🐟
sites.northwestern.edu/parvezlab/
sites.northwestern.edu/parvezlab/
My collaborative work with @james-gagnon.bsky.social lab is now on Biorxiv. We combined the high throughput in vivo perturbation abilities of #MIC-Drop 🎤🫳with unbiased molecular phenotyping abilities of scRnaseq. Some very cool finding and a lot of data to explore more!! #zebrafish 🐟
To dissect the gene regulatory networks used to build organisms, we need Perturb-seq-like tools that work in whole animals.
For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq.
www.biorxiv.org/content/10.1...
For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq.
www.biorxiv.org/content/10.1...
MIC-Drop-seq: Scalable single-cell phenotyping of mutant vertebrate embryos
Pooled perturbation screens can reveal cellular regulatory networks, yet scaling these techniques for large-scale screens in animals remains challenging. To address this, we developed MIC-Drop-seq, wh...
www.biorxiv.org
June 3, 2025 at 1:03 AM
My collaborative work with @james-gagnon.bsky.social lab is now on Biorxiv. We combined the high throughput in vivo perturbation abilities of #MIC-Drop 🎤🫳with unbiased molecular phenotyping abilities of scRnaseq. Some very cool finding and a lot of data to explore more!! #zebrafish 🐟
Reposted by Saba Parvez
The NIH overhead cut doesn't just hurt universities.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.
2. While NSF and NIH indeed have a mission to fund specific research innovations via grantmaking, they do a lot more than that.
Their principal role is support a scientific ecosystem in the United States, that includes everything from education and training to infrastructure and communication.
Their principal role is support a scientific ecosystem in the United States, that includes everything from education and training to infrastructure and communication.
February 8, 2025 at 2:03 AM
The NIH overhead cut doesn't just hurt universities.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.