siTOOLs Biotech
@sitoolsbiotech.bsky.social
🧬 We drive RNA Research with a complex pooling approach to RNAi, RNA-Seq and Ribosome Profiling.
🌎📍Based in the biotech cluster Martinsried, Germany.
#RNAi #RNA-Seq #Ribo-Seq.
https://www.sitoolsbiotech.com
🌎📍Based in the biotech cluster Martinsried, Germany.
#RNAi #RNA-Seq #Ribo-Seq.
https://www.sitoolsbiotech.com
🧬 A new report in Science Advances highlights how nonstop-mutations can alter translation initiation
Point mutations can affect all levels of gene expression, leading to #dysregulation and #cancer. Pal et al., Sci. Adv.
Read the full paper here: www.science.org/doi/full/10....
#siPOOLs #raPOOLs
Point mutations can affect all levels of gene expression, leading to #dysregulation and #cancer. Pal et al., Sci. Adv.
Read the full paper here: www.science.org/doi/full/10....
#siPOOLs #raPOOLs
Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation
Extending a protein at its end affects its stability, but also its translation efficiency and even selection of its start.
www.science.org
February 19, 2025 at 10:17 AM
🧬 A new report in Science Advances highlights how nonstop-mutations can alter translation initiation
Point mutations can affect all levels of gene expression, leading to #dysregulation and #cancer. Pal et al., Sci. Adv.
Read the full paper here: www.science.org/doi/full/10....
#siPOOLs #raPOOLs
Point mutations can affect all levels of gene expression, leading to #dysregulation and #cancer. Pal et al., Sci. Adv.
Read the full paper here: www.science.org/doi/full/10....
#siPOOLs #raPOOLs