Sina Taefehshokr
@sinataefehshokr.bsky.social
DVM, MSc
PhD student | Immunology | Asthma 🫁
University of Manitoba 🇨🇦
PhD student | Immunology | Asthma 🫁
University of Manitoba 🇨🇦
Pinned
public-pages-files-2025.frontiersin.org
Our new paper in Frontiers in Allergy!
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
Our new paper in Frontiers in Allergy!
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
public-pages-files-2025.frontiersin.org
February 5, 2026 at 4:41 PM
Our new paper in Frontiers in Allergy!
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
PTX3 is elevated in asthmatics, but in a type 2–low asthma mouse model, PTX3 knockout worsened disease with more neutrophilia, IL-17A, IgE, and AHR. PTX3 appears protective, not pathogenic.
public-pages-files-2025.frontiersin.org/journals/all...
Our new #PLOSONE study is out! 📢
Deleting TSLPR in chronic HDM asthma lowered AHR and cut IL-4/IL-13 + HDM-IgE but eosinophils, mucus, and collagen didn’t budge 🤷♂️.
#Asthma biology stays complicated.
journals.plos.org/plosone/arti...
Deleting TSLPR in chronic HDM asthma lowered AHR and cut IL-4/IL-13 + HDM-IgE but eosinophils, mucus, and collagen didn’t budge 🤷♂️.
#Asthma biology stays complicated.
journals.plos.org/plosone/arti...
TSLPR deficiency attenuates AHR independently of eosinophilia and mucus secretion in a chronic HDM mouse model of allergic asthma
Background Asthma is marked by chronic airway inflammation, immune dysregulation, and airway remodeling. While TSLP is known to influence allergic diseases like asthma, the role of TSLPR in airway rem...
journals.plos.org
November 24, 2025 at 12:26 AM
Our new #PLOSONE study is out! 📢
Deleting TSLPR in chronic HDM asthma lowered AHR and cut IL-4/IL-13 + HDM-IgE but eosinophils, mucus, and collagen didn’t budge 🤷♂️.
#Asthma biology stays complicated.
journals.plos.org/plosone/arti...
Deleting TSLPR in chronic HDM asthma lowered AHR and cut IL-4/IL-13 + HDM-IgE but eosinophils, mucus, and collagen didn’t budge 🤷♂️.
#Asthma biology stays complicated.
journals.plos.org/plosone/arti...
I had the pleasure of giving an oral presentation at the Prairies Infectious and Immunology Network (PIIN) 2025 conference in Saskatoon, where I shared our work on the role of Pentraxin 3 in Type-2 low asthma 🫁
Grateful for the opportunity to present and connect!
#PIIN2025 #Immunology #Asthma
Grateful for the opportunity to present and connect!
#PIIN2025 #Immunology #Asthma
October 3, 2025 at 3:20 PM
I had the pleasure of giving an oral presentation at the Prairies Infectious and Immunology Network (PIIN) 2025 conference in Saskatoon, where I shared our work on the role of Pentraxin 3 in Type-2 low asthma 🫁
Grateful for the opportunity to present and connect!
#PIIN2025 #Immunology #Asthma
Grateful for the opportunity to present and connect!
#PIIN2025 #Immunology #Asthma