Simone Mozzachiodi
simonemozzachiodi.bsky.social
Simone Mozzachiodi
@simonemozzachiodi.bsky.social
Postdoc in Kiran Patil's lab at Cambridge, UK. Previously PhD student at Gianni Liti's lab in Nice, France. Interested in microbes (genomes, evolution, communities and metabolism)
Reposted by Simone Mozzachiodi
🆕 Vacancy! We're looking for a Research Scientist to work on novel platforms for sustainable myco-food production and precision fermentation.

💷 £37,500 to £40,240
🗓️ Apply by 30 November 2025
➡️ buff.ly/6LKIB1y
November 7, 2025 at 3:00 PM
Reposted by Simone Mozzachiodi
The #Yeast2025 meeting has finally reached its end after four days of exciting talks, posters and networking activities.
Stay tuned for the upcoming special issue about the conference!
More infos will follow in the next coming weeks. 🙂
July 25, 2025 at 11:04 AM
Reposted by Simone Mozzachiodi
@pjboynton.bsky.social advertises our upcoming special issue about the #Yeast2025 conference in Paris
July 24, 2025 at 1:38 PM
Reposted by Simone Mozzachiodi
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.

www.biorxiv.org/content/10.1...
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
www.biorxiv.org
July 3, 2025 at 8:29 AM
Reposted by Simone Mozzachiodi
Excited to share some key details on our latest research in @natmicrobiol.nature.com reporting intra-cellular accumulation of #PFAS (aka forever chemicals) by certain human gut bacteria. #microsky #mevosky #microbiomesky
www.nature.com/articles/s41...
July 2, 2025 at 2:57 PM
Reposted by Simone Mozzachiodi
Latest study from the lab is online today (and another will be out tomorrow, stay tuned:)). We profiled effect of >1700 chemicals (drugs, pesticides,...) on secretion of amines (involved in gut-brain and gut-immune axis. ) by human gut bacteria. Brilliant work by @skamrad.bsky.social and Tara Davis
Stephan Kamrad and Tara Davis in the Patil lab at the MRC Toxicology Unit have identified that some drugs and environmental contaminants alter gut bacterial amine metabolism.

Find out more here: buff.ly/5akzsgs
@kiranrpatil.bsky.social @skamrad.bsky.social
June 30, 2025 at 6:44 PM
Reposted by Simone Mozzachiodi
incredible work by an incredible scientist (and friend)! very beautiful figures too www.cell.com/cell-systems...
The molecular landscape of cellular metal ion biology
Aulakh et al. systematically investigated how metal ion availability impacts yeast biochemistry. Their metallomic, proteomic, and genetic screens reveal the widespread metal concentration dependence o...
www.cell.com
June 13, 2025 at 7:21 PM
Reposted by Simone Mozzachiodi
In the latest #Yeast research article of the series #FantasticYeasts, Pei-Jie Han, Feng-Yan Bai & team describe a new yeast species isolated from a Chinese forest: Saccharomycopsis yichangensis, that can prey on Saccharomyces cerevisiae and other yeasts 😲

onlinelibrary.wiley.com/doi/10.1002/...
Saccharomycopsis yichangensis sp. nov., a Novel Predacious Yeast Species Isolated From Soil
Saccharomycopsis yichangensis sp. nov. occurs in soil from a subtropical forest in central China. This novel species is homothallic and produces asci containing four spheroidal ascospores, which can ...
onlinelibrary.wiley.com
May 22, 2025 at 9:21 AM
Reposted by Simone Mozzachiodi
Check out our new preprint!
We systematically map proteomic and metabolomic interactions between >100 pairs of gut bacteria, detecting metabolic interactions and functionally-related clusters of proteins.

www.biorxiv.org/content/10.1...

@kiranrpatil.bsky.social
Interspecies interactions drive bacterial proteome reorganisation and emergent metabolism
Species in microbial communities must respond to the presence of others to stave off resource competition or to capitalise on new resources that may become available due to additional metabolic activi...
www.biorxiv.org
May 15, 2025 at 10:13 AM
Reposted by Simone Mozzachiodi
Hi everyone! "Yeast" is looking for its next journal cover for the upcoming 2025 issues. If you have beautiful yeast images that you would like to see on our front cover, please send them to
YEAST@wiley.com

Have a nice day 🙂
February 28, 2025 at 8:36 AM
Reposted by Simone Mozzachiodi
🧬 Save the date! The EMBO Workshop "The Immune System of Bacteria" will uncover groundbreaking insights into bacterial defense systems. Join us April 8-10, 2025, at Institut Pasteur, Paris. Submit your abstracts by Feb. 28 👉 https://www.sisb2025.conferences-pasteur.org/home
January 16, 2025 at 2:45 PM
Reposted by Simone Mozzachiodi
Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years!

"Prolonged persistence of mutagenic DNA lesions in somatic cells"
www.nature.com/articles/s41...
Prolonged persistence of mutagenic DNA lesions in somatic cells - Nature
Persistent DNA lesions can occur throughout the human lifespan and can remain in the genome of affected cells for several years and generate a substantial proportion of the mutational burden.
www.nature.com
January 15, 2025 at 5:21 PM